A focussed analysis of β-cyclodextrins for quinoxaline derivatives synthesis

Cyclodextrins (CDs), which are a type of cyclic oligosaccharides, are widely used in supramolecular chemistry. For example, they can be used to encapsulate volatile compounds, such as drugs, within their hydrophobic cavity. This encapsulation reduces the volatility of the compounds and helps to reta...

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Main Authors: Khatoon, Hena, Abdul Malek, Emilia
Format: Article
Published: Bentham Science Publishers 2024
Online Access:http://psasir.upm.edu.my/id/eprint/117050/
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author Khatoon, Hena
Abdul Malek, Emilia
author_facet Khatoon, Hena
Abdul Malek, Emilia
author_sort Khatoon, Hena
building UPM Institutional Repository
collection Online Access
description Cyclodextrins (CDs), which are a type of cyclic oligosaccharides, are widely used in supramolecular chemistry. For example, they can be used to encapsulate volatile compounds, such as drugs, within their hydrophobic cavity. This encapsulation reduces the volatility of the compounds and helps to retain their desired properties. Due to its extraordinary properties, cyclodextrins have been utilized as catalysts in numerous organic synthesis processes. An intrinsic objective of organic chemists is to optimize the efficacy of organic synthesis through the mitigation of chemical waste and energy expenditure. Utilizing water as a green solvent is, therefore, economical, environmentally sustainable, and secure. It appears that employing water in conjunction with a recyclable catalyst is the most effective method for supramolecular catalysis. As a consequence, we focused this review on the use of water as a solvent and cyclodextrin as a polymer catalyst to produce quinoxaline derivatives in an environmentally friendly and sustainable manner.
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spelling upm-1170502025-04-23T07:00:24Z http://psasir.upm.edu.my/id/eprint/117050/ A focussed analysis of β-cyclodextrins for quinoxaline derivatives synthesis Khatoon, Hena Abdul Malek, Emilia Cyclodextrins (CDs), which are a type of cyclic oligosaccharides, are widely used in supramolecular chemistry. For example, they can be used to encapsulate volatile compounds, such as drugs, within their hydrophobic cavity. This encapsulation reduces the volatility of the compounds and helps to retain their desired properties. Due to its extraordinary properties, cyclodextrins have been utilized as catalysts in numerous organic synthesis processes. An intrinsic objective of organic chemists is to optimize the efficacy of organic synthesis through the mitigation of chemical waste and energy expenditure. Utilizing water as a green solvent is, therefore, economical, environmentally sustainable, and secure. It appears that employing water in conjunction with a recyclable catalyst is the most effective method for supramolecular catalysis. As a consequence, we focused this review on the use of water as a solvent and cyclodextrin as a polymer catalyst to produce quinoxaline derivatives in an environmentally friendly and sustainable manner. Bentham Science Publishers 2024-03-11 Article PeerReviewed Khatoon, Hena and Abdul Malek, Emilia (2024) A focussed analysis of β-cyclodextrins for quinoxaline derivatives synthesis. Current Organic Chemistry, 28 (5). pp. 368-374. ISSN 1385-2728; eISSN: 1385-5348 https://www.eurekaselect.com/article/139088 10.2174/0113852728295463240216074814
spellingShingle Khatoon, Hena
Abdul Malek, Emilia
A focussed analysis of β-cyclodextrins for quinoxaline derivatives synthesis
title A focussed analysis of β-cyclodextrins for quinoxaline derivatives synthesis
title_full A focussed analysis of β-cyclodextrins for quinoxaline derivatives synthesis
title_fullStr A focussed analysis of β-cyclodextrins for quinoxaline derivatives synthesis
title_full_unstemmed A focussed analysis of β-cyclodextrins for quinoxaline derivatives synthesis
title_short A focussed analysis of β-cyclodextrins for quinoxaline derivatives synthesis
title_sort focussed analysis of β-cyclodextrins for quinoxaline derivatives synthesis
url http://psasir.upm.edu.my/id/eprint/117050/
http://psasir.upm.edu.my/id/eprint/117050/
http://psasir.upm.edu.my/id/eprint/117050/