Cytotoxic and bacteriocidal activities of psychotria rostrata

Quadrigemine B, a major alkaloid of Psychotria rostrata, was shown to be cytotoxic with HEp-2 cells and normal human lymphocytes. The cytotoxicity was time- and dose-dependent. Bacteriocidal activity was also shown by this compound toward Escherichia coli and Staphylococcus aureus.

Bibliographic Details
Main Authors: Mahmud, Zurinah, Musa, Mustaffa, Ismail, Norhayati, Lajis, Nordin H.
Format: Article
Published: Informa Healthcare 1993
Online Access:http://psasir.upm.edu.my/id/eprint/116655/
Description
Summary:Quadrigemine B, a major alkaloid of Psychotria rostrata, was shown to be cytotoxic with HEp-2 cells and normal human lymphocytes. The cytotoxicity was time- and dose-dependent. Bacteriocidal activity was also shown by this compound toward Escherichia coli and Staphylococcus aureus.