Screening of Bunyaviridae in rodents from Klang Valley, Malaysia

Pest rodents, such as Rattus rattus (black rat) and Rattus norvegicus (Norway rat), are common in urban and rural environments which are in close proximity to human populations. Rodents serve as important reservoirs for a wide range of diseases. In Asia and Europe, hantaviruses from the Bunyaviridae...

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Main Authors: Abd Rahaman, Nor Yasmin, Muhammad Arif, Muhammad Faiz, Hassan, Latiffah, Awang Hamat, Rukman
Format: Conference or Workshop Item
Language:English
Published: Malaysian Association of Veterinary Pathology 2024
Online Access:http://psasir.upm.edu.my/id/eprint/116479/
http://psasir.upm.edu.my/id/eprint/116479/1/116479.pdf
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author Abd Rahaman, Nor Yasmin
Muhammad Arif, Muhammad Faiz
Hassan, Latiffah
Awang Hamat, Rukman
author_facet Abd Rahaman, Nor Yasmin
Muhammad Arif, Muhammad Faiz
Hassan, Latiffah
Awang Hamat, Rukman
author_sort Abd Rahaman, Nor Yasmin
building UPM Institutional Repository
collection Online Access
description Pest rodents, such as Rattus rattus (black rat) and Rattus norvegicus (Norway rat), are common in urban and rural environments which are in close proximity to human populations. Rodents serve as important reservoirs for a wide range of diseases. In Asia and Europe, hantaviruses from the Bunyaviridae family are commonly associated with rodent-borne zoonotic viruses that cause hemorrhagic fever with renal syndrome (HFRS) in humans. Studying these rats for rodent-borne zoonotic viruses offers unique advantages due to their ecological relevance, natural exposure to pathogens, and interactions with human habitats. Little information is known about the diversity of zoonotic viruses circulating among rodent species in Malaysia, especially Bunyaviridae. Exploring this will contribute to better future preparedness and response strategies for emerging infectious diseases, particularly in Malaysia. In this study, a total of 130 rodents were captured and screened for Bunyaviridae families using RT-PCR assays. However, none of the samples tested positive for this virus family. These results suggest that bunyavirus is not circulating in the studied rodent populations in the Klang Valley, Malaysia. However, since pest rodents often interact with wildlife and domestic animals, as well as humans, this turns out making them among the important nodes in disease transmission networks.
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institution Universiti Putra Malaysia
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spelling upm-1164792025-04-09T01:52:32Z http://psasir.upm.edu.my/id/eprint/116479/ Screening of Bunyaviridae in rodents from Klang Valley, Malaysia Abd Rahaman, Nor Yasmin Muhammad Arif, Muhammad Faiz Hassan, Latiffah Awang Hamat, Rukman Pest rodents, such as Rattus rattus (black rat) and Rattus norvegicus (Norway rat), are common in urban and rural environments which are in close proximity to human populations. Rodents serve as important reservoirs for a wide range of diseases. In Asia and Europe, hantaviruses from the Bunyaviridae family are commonly associated with rodent-borne zoonotic viruses that cause hemorrhagic fever with renal syndrome (HFRS) in humans. Studying these rats for rodent-borne zoonotic viruses offers unique advantages due to their ecological relevance, natural exposure to pathogens, and interactions with human habitats. Little information is known about the diversity of zoonotic viruses circulating among rodent species in Malaysia, especially Bunyaviridae. Exploring this will contribute to better future preparedness and response strategies for emerging infectious diseases, particularly in Malaysia. In this study, a total of 130 rodents were captured and screened for Bunyaviridae families using RT-PCR assays. However, none of the samples tested positive for this virus family. These results suggest that bunyavirus is not circulating in the studied rodent populations in the Klang Valley, Malaysia. However, since pest rodents often interact with wildlife and domestic animals, as well as humans, this turns out making them among the important nodes in disease transmission networks. Malaysian Association of Veterinary Pathology 2024 Conference or Workshop Item NonPeerReviewed text en http://psasir.upm.edu.my/id/eprint/116479/1/116479.pdf Abd Rahaman, Nor Yasmin and Muhammad Arif, Muhammad Faiz and Hassan, Latiffah and Awang Hamat, Rukman (2024) Screening of Bunyaviridae in rodents from Klang Valley, Malaysia. In: 15th MAVP Scientific Conference 2024, 26-28 Jul. 2024, Melaka. (p. 54). (Submitted)
spellingShingle Abd Rahaman, Nor Yasmin
Muhammad Arif, Muhammad Faiz
Hassan, Latiffah
Awang Hamat, Rukman
Screening of Bunyaviridae in rodents from Klang Valley, Malaysia
title Screening of Bunyaviridae in rodents from Klang Valley, Malaysia
title_full Screening of Bunyaviridae in rodents from Klang Valley, Malaysia
title_fullStr Screening of Bunyaviridae in rodents from Klang Valley, Malaysia
title_full_unstemmed Screening of Bunyaviridae in rodents from Klang Valley, Malaysia
title_short Screening of Bunyaviridae in rodents from Klang Valley, Malaysia
title_sort screening of bunyaviridae in rodents from klang valley, malaysia
url http://psasir.upm.edu.my/id/eprint/116479/
http://psasir.upm.edu.my/id/eprint/116479/1/116479.pdf