Unveiling drimenol: a phytochemical with multifaceted bioactivities
Drimenol, a phytochemical with a distinct odor is found in edible aromatic plants, such as Polygonum minus (known as kesum in Malaysia) and Drimys winteri. Recently, drimenol has received increasing attention owing to its diverse biological activities. This review offers the first extensive overview...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Multidisciplinary Digital Publishing Institute (MDPI)
2024
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/116264/ http://psasir.upm.edu.my/id/eprint/116264/1/116264.pdf |
| _version_ | 1848866963311296512 |
|---|---|
| author | Yang, Zhongming Chan, Kim Wei Abu Bakar, Md Zuki Deng, Xi |
| author_facet | Yang, Zhongming Chan, Kim Wei Abu Bakar, Md Zuki Deng, Xi |
| author_sort | Yang, Zhongming |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Drimenol, a phytochemical with a distinct odor is found in edible aromatic plants, such as Polygonum minus (known as kesum in Malaysia) and Drimys winteri. Recently, drimenol has received increasing attention owing to its diverse biological activities. This review offers the first extensive overview of drimenol, covering its sources, bioactivities, and derivatives. Notably, drimenol possesses a wide spectrum of biological activities, including antifungal, antibacterial, anti-insect, antiparasitic, cytotoxic, anticancer, and antioxidant effects. Moreover, some mechanisms of its activities, such as its antifungal effects against human mycoses and anticancer activities, have been investigated. However, there are still several crucial issues in the research on drimenol, such as the lack of experimental understanding of its pharmacokinetics, bioavailability, and toxicity. By synthesizing current research findings, this review aims to present a holistic understanding of drimenol, paving the way for future studies and its potential utilization in diverse fields. |
| first_indexed | 2025-11-15T14:28:57Z |
| format | Article |
| id | upm-116264 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T14:28:57Z |
| publishDate | 2024 |
| publisher | Multidisciplinary Digital Publishing Institute (MDPI) |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1162642025-03-24T03:20:17Z http://psasir.upm.edu.my/id/eprint/116264/ Unveiling drimenol: a phytochemical with multifaceted bioactivities Yang, Zhongming Chan, Kim Wei Abu Bakar, Md Zuki Deng, Xi Drimenol, a phytochemical with a distinct odor is found in edible aromatic plants, such as Polygonum minus (known as kesum in Malaysia) and Drimys winteri. Recently, drimenol has received increasing attention owing to its diverse biological activities. This review offers the first extensive overview of drimenol, covering its sources, bioactivities, and derivatives. Notably, drimenol possesses a wide spectrum of biological activities, including antifungal, antibacterial, anti-insect, antiparasitic, cytotoxic, anticancer, and antioxidant effects. Moreover, some mechanisms of its activities, such as its antifungal effects against human mycoses and anticancer activities, have been investigated. However, there are still several crucial issues in the research on drimenol, such as the lack of experimental understanding of its pharmacokinetics, bioavailability, and toxicity. By synthesizing current research findings, this review aims to present a holistic understanding of drimenol, paving the way for future studies and its potential utilization in diverse fields. Multidisciplinary Digital Publishing Institute (MDPI) 2024-09-05 Article PeerReviewed text en cc_by_4 http://psasir.upm.edu.my/id/eprint/116264/1/116264.pdf Yang, Zhongming and Chan, Kim Wei and Abu Bakar, Md Zuki and Deng, Xi (2024) Unveiling drimenol: a phytochemical with multifaceted bioactivities. Plants, 13 (17). art. no. 2492. pp. 1-38. ISSN 2223-7747 https://www.mdpi.com/2223-7747/13/17/2492 10.3390/plants13172492 |
| spellingShingle | Yang, Zhongming Chan, Kim Wei Abu Bakar, Md Zuki Deng, Xi Unveiling drimenol: a phytochemical with multifaceted bioactivities |
| title | Unveiling drimenol: a phytochemical with multifaceted bioactivities |
| title_full | Unveiling drimenol: a phytochemical with multifaceted bioactivities |
| title_fullStr | Unveiling drimenol: a phytochemical with multifaceted bioactivities |
| title_full_unstemmed | Unveiling drimenol: a phytochemical with multifaceted bioactivities |
| title_short | Unveiling drimenol: a phytochemical with multifaceted bioactivities |
| title_sort | unveiling drimenol: a phytochemical with multifaceted bioactivities |
| url | http://psasir.upm.edu.my/id/eprint/116264/ http://psasir.upm.edu.my/id/eprint/116264/ http://psasir.upm.edu.my/id/eprint/116264/ http://psasir.upm.edu.my/id/eprint/116264/1/116264.pdf |