Optical fiber SERS sensors: Unveiling advances, challenges, and applications in a miniaturized technology

In both the scientific and technological fields, there is a fundamental need for highly sensitive and specific detection of chemical traces or biological targets at the single molecule level. To achieve this, sensor technology based on surface-enhanced Raman scattering (SERS) is a promising approach...

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Main Authors: Gangwar, R.K., Pathak, A.K., Chiavaioli, F., Abu Bakar, M.H., Kamil, Y.M., Mahdi, M.A., Singh, V.K.
Format: Article
Language:English
Published: Elsevier 2024
Online Access:http://psasir.upm.edu.my/id/eprint/116240/
http://psasir.upm.edu.my/id/eprint/116240/1/116240.pdf
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author Gangwar, R.K.
Pathak, A.K.
Chiavaioli, F.
Abu Bakar, M.H.
Kamil, Y.M.
Mahdi, M.A.
Singh, V.K.
author_facet Gangwar, R.K.
Pathak, A.K.
Chiavaioli, F.
Abu Bakar, M.H.
Kamil, Y.M.
Mahdi, M.A.
Singh, V.K.
author_sort Gangwar, R.K.
building UPM Institutional Repository
collection Online Access
description In both the scientific and technological fields, there is a fundamental need for highly sensitive and specific detection of chemical traces or biological targets at the single molecule level. To achieve this, sensor technology based on surface-enhanced Raman scattering (SERS) is a promising approach due to its extremely narrow linewidth, high sensitivity and signal-to-noise ratio, target specificity and ability for non-destructive and multiplexed monitoring of chemical or biological species. Raman scattering is a phenomenon that occurs due to the interaction between photons and molecules depending on the kinetic modes of the analytes, providing unique fingerprints that enable real-time detection of chemical or biological species. By monitoring molecular activity in the vicinity of nanostructured surfaces, SERS-based sensors not only provide valuable insight into molecular interaction or binding, but also serve as a reference for the further development of powerful and optimized detection methods. While the existing reviews on SERS devices mainly focus on classical planar or chip-based substrates, a detailed review covering various strategies for highly sensitive SERS sensors based on optical fibers, nanostructuring of the fiber surface, their working mechanisms and practical applications is still pending. Only recent advances in nanotechnology and related equipment have made it possible to effectively and reliably use optical fibers as SERS substrates. Our aim is therefore to report on the current status of SERS fiber technologies, their detection mechanisms. We also highlight different fiber geometries used so far to develop miniaturized lab-on-fiber devices, and the extensive range of applications associated with these advances by emphasizing the advantages, limitations and future perspectives in this field.
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spelling upm-1162402025-04-10T06:43:18Z http://psasir.upm.edu.my/id/eprint/116240/ Optical fiber SERS sensors: Unveiling advances, challenges, and applications in a miniaturized technology Gangwar, R.K. Pathak, A.K. Chiavaioli, F. Abu Bakar, M.H. Kamil, Y.M. Mahdi, M.A. Singh, V.K. In both the scientific and technological fields, there is a fundamental need for highly sensitive and specific detection of chemical traces or biological targets at the single molecule level. To achieve this, sensor technology based on surface-enhanced Raman scattering (SERS) is a promising approach due to its extremely narrow linewidth, high sensitivity and signal-to-noise ratio, target specificity and ability for non-destructive and multiplexed monitoring of chemical or biological species. Raman scattering is a phenomenon that occurs due to the interaction between photons and molecules depending on the kinetic modes of the analytes, providing unique fingerprints that enable real-time detection of chemical or biological species. By monitoring molecular activity in the vicinity of nanostructured surfaces, SERS-based sensors not only provide valuable insight into molecular interaction or binding, but also serve as a reference for the further development of powerful and optimized detection methods. While the existing reviews on SERS devices mainly focus on classical planar or chip-based substrates, a detailed review covering various strategies for highly sensitive SERS sensors based on optical fibers, nanostructuring of the fiber surface, their working mechanisms and practical applications is still pending. Only recent advances in nanotechnology and related equipment have made it possible to effectively and reliably use optical fibers as SERS substrates. Our aim is therefore to report on the current status of SERS fiber technologies, their detection mechanisms. We also highlight different fiber geometries used so far to develop miniaturized lab-on-fiber devices, and the extensive range of applications associated with these advances by emphasizing the advantages, limitations and future perspectives in this field. Elsevier 2024-04-12 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/116240/1/116240.pdf Gangwar, R.K. and Pathak, A.K. and Chiavaioli, F. and Abu Bakar, M.H. and Kamil, Y.M. and Mahdi, M.A. and Singh, V.K. (2024) Optical fiber SERS sensors: Unveiling advances, challenges, and applications in a miniaturized technology. Coordination Chemistry Reviews, 510. art. no. 215861. ISSN 0010-8545; eISSN: 0010-8545 https://linkinghub.elsevier.com/retrieve/pii/S0010854524002078 10.1016/j.ccr.2024.215861
spellingShingle Gangwar, R.K.
Pathak, A.K.
Chiavaioli, F.
Abu Bakar, M.H.
Kamil, Y.M.
Mahdi, M.A.
Singh, V.K.
Optical fiber SERS sensors: Unveiling advances, challenges, and applications in a miniaturized technology
title Optical fiber SERS sensors: Unveiling advances, challenges, and applications in a miniaturized technology
title_full Optical fiber SERS sensors: Unveiling advances, challenges, and applications in a miniaturized technology
title_fullStr Optical fiber SERS sensors: Unveiling advances, challenges, and applications in a miniaturized technology
title_full_unstemmed Optical fiber SERS sensors: Unveiling advances, challenges, and applications in a miniaturized technology
title_short Optical fiber SERS sensors: Unveiling advances, challenges, and applications in a miniaturized technology
title_sort optical fiber sers sensors: unveiling advances, challenges, and applications in a miniaturized technology
url http://psasir.upm.edu.my/id/eprint/116240/
http://psasir.upm.edu.my/id/eprint/116240/
http://psasir.upm.edu.my/id/eprint/116240/
http://psasir.upm.edu.my/id/eprint/116240/1/116240.pdf