Evaluation of pancreatic cancer cell lines as a source of cancer stem cells (CSC) and their utilisation for assessing anti-CSC activities of KRAS binders
Background: High incidence of recurrence has been recorded at 80% of pancreatic ductal adenocarcinoma (PDAC) cases, despite tumour resection and an adjuvant chemotherapy with gemcitabine are prescribed. Pancreatic cancer stem cells (CSCs) are believed to have initiated recurrent PDAC. Growing ev...
| Main Author: | Teh, Yuan Han |
|---|---|
| Format: | Thesis |
| Language: | English |
| Published: |
2020
|
| Subjects: | |
| Online Access: | http://psasir.upm.edu.my/id/eprint/116093/ http://psasir.upm.edu.my/id/eprint/116093/1/116093.pdf |
Similar Items
Emerging role of the KRAS-PDK1 axis in pancreatic cancer
by: Ferro, R., et al.
Published: (2014)
by: Ferro, R., et al.
Published: (2014)
Surgical Management in Patients With Pancreatic Cancer: a Queensland Perspective
by: Wylie, N., et al.
Published: (2013)
by: Wylie, N., et al.
Published: (2013)
Cytotoxicity of SRJ23 and its derivatives, expression and SRJ23 binding of KRas G12V oncoprotein
by: Tan, Michelle Siying
Published: (2017)
by: Tan, Michelle Siying
Published: (2017)
Mesoporous silica nanoparticles as anticancer drug carriers in pancreatic cancer treatment
by: Chung, Shei Li
Published: (2025)
by: Chung, Shei Li
Published: (2025)
LY2495655, an antimyostatin antibody in pancreatic cancer: a randomized phase 2 trial
by: Golan, Talia, et al.
Published: (2018)
by: Golan, Talia, et al.
Published: (2018)
Development of Thermo-responsive materials for pancreatic cancer management
by: ElSherbeny, Amr Moustafa Said Moustafa
Published: (2024)
by: ElSherbeny, Amr Moustafa Said Moustafa
Published: (2024)
Unravelling the tumour- and cancer stem cell (CSC)-regulatory roles of miR-3934-5p in human breast cancer
by: Chong, Zhi Xiong
Published: (2024)
by: Chong, Zhi Xiong
Published: (2024)
Association Between Ultraviolet Radiation, Skin Sun Sensitivity and Risk of Pancreatic Cancer
by: Tran, B., et al.
Published: (2013)
by: Tran, B., et al.
Published: (2013)
Role of the Hedgehog pathway in the pancreatic tumour microenvironment
by: Saini, Francesca
Published: (2014)
by: Saini, Francesca
Published: (2014)
More than just a KRAS inhibitor: DCAI abrogates the self-renewal of pancreatic cancer stem cells in vitro
by: Yuan, Han Teh, et al.
Published: (2023)
by: Yuan, Han Teh, et al.
Published: (2023)
Association between autophagy and KRAS mutation with
clinicopathological variables in colorectal cancer patients
by: Awi, Noel Jacques, et al.
Published: (2021)
by: Awi, Noel Jacques, et al.
Published: (2021)
Targeting thioredoxin reductase in pancreatic cancer
by: Alhadyan, Khaled
Published: (2019)
by: Alhadyan, Khaled
Published: (2019)
Association between hypermethylation of DNA repetitive elements in white blood cell DNA and pancreatic cancer
by: Neale, R., et al.
Published: (2014)
by: Neale, R., et al.
Published: (2014)
Antioxidant and phytochemical properties and in vitro cancer chemopreventive effects of averrhoa bilimbi l. extract on human breast and cervical adenocarcinoma
by: Yan, See Wan
Published: (2012)
by: Yan, See Wan
Published: (2012)
Interplay of autophagy and cancer stem cells in hepatocellular carcinoma
by: Wong, M. M. T., et al.
Published: (2021)
by: Wong, M. M. T., et al.
Published: (2021)
Prevalence of pancreatitis in cats presented to University Veterinary Hospital UPM from 2013-2014
by: Lim, May Lyn
Published: (2014)
by: Lim, May Lyn
Published: (2014)
Enhancement of in vitro effects of polymeric nanoparticle encapsulated tamoxifin compared to tamoxifen in MCF-7 breast cancer cell line
by: Tung, En En
Published: (2012)
by: Tung, En En
Published: (2012)
Cost of cancer care for patients undergoing chemotherapy: The Elements of Cancer Care study
by: Ward, R., et al.
Published: (2015)
by: Ward, R., et al.
Published: (2015)
In Vitro And In Vivo Studies On The
Complementary Effects Of
Standardized Ethanolic Orthosiphon
Stamineus Extract On Pancreatic
Cancer Cells
by: Salem Yehya, Ashwaq Hamid
Published: (2018)
by: Salem Yehya, Ashwaq Hamid
Published: (2018)
The Impact of Inflammation on Pancreatic ß-Cell Metabolism, Function and Failure in T1DM and T2DM: Commonalities and Differences
by: Newsholme, Philip, et al.
Published: (2013)
by: Newsholme, Philip, et al.
Published: (2013)
Synergistic effects of Gefitinib and Paclitaxel in breast cancer treatment using cockle shell-derived nanoparticle
by: Chemmalar, Sangaran
Published: (2023)
by: Chemmalar, Sangaran
Published: (2023)
Cell-based assays for evaluation of autophagy in cancers
by: Pang, Siew Wai *, et al.
Published: (2019)
by: Pang, Siew Wai *, et al.
Published: (2019)
Prevalence and predictors of depression and anxiety among oncology patients receiving chemotherapy in public hospitals in Peninsular Malaysia
by: Remesh Kumar, Mamta Vesudave
Published: (2018)
by: Remesh Kumar, Mamta Vesudave
Published: (2018)
Study of anti-cancer mechanism: Neolamarckia cadamba leaves exposed with electric field on HeLa cell
by: Mohamad Ishak, Daing Noor Farhanah, et al.
Published: (2018)
by: Mohamad Ishak, Daing Noor Farhanah, et al.
Published: (2018)
Anti-breast cancer effect of eupatorin in vitro and in vivo
by: Abd Razak, Nursyamirah
Published: (2018)
by: Abd Razak, Nursyamirah
Published: (2018)
Role of epigallocatechin-3-gallate from green tea in iron chelation and endoplasmic reticulum stress pathway in colorectal cancer cells
by: Md Nesran, Zarith Nameyra
Published: (2018)
by: Md Nesran, Zarith Nameyra
Published: (2018)
Apoptosis and cell cycle arrest of MCF-7R breast carcinoma cells by bis(phosphane)copper(I) thiocarbamides derivative compounds
by: Ooi, Kah Kooi
Published: (2017)
by: Ooi, Kah Kooi
Published: (2017)
Enrichment of Colorectal Cancer Stem Cells by Spheroidal Culture and Gene Expression Analysis of Selected ABC Transporters
by: Vimalan, Rengganaten
Published: (2016)
by: Vimalan, Rengganaten
Published: (2016)
Koenimbin induces apoptosis in MCF7 breast cancer cells with antiproliferation effect on MCF7-derived cancer stem cell (CD44+/CD24-/low) in vitro / Fatemeh Ahmadipour
by: Fatemeh, Ahmadipour
Published: (2018)
by: Fatemeh, Ahmadipour
Published: (2018)
Anti-tumour efficacy of human mesenchymal stem cell expressing trail on lung cancer cell lines-derived cancer stem cell
by: Shaik M Fakiruddin, Shaik Ahmad Kamal
Published: (2021)
by: Shaik M Fakiruddin, Shaik Ahmad Kamal
Published: (2021)
Quality of life among cancer patients undergoing chemotherapy in government hospitals in Peninsular Malaysia
by: Subramaniam, Suhasinee
Published: (2018)
by: Subramaniam, Suhasinee
Published: (2018)
Polyadenylation as a target for the treatment of breast cancer
by: Thiyab, Asraa
Published: (2025)
by: Thiyab, Asraa
Published: (2025)
The role of mitochondria and KATP channels in the vasodilatation response to simvastatin: comparison with the effects of simvastatin in pancreatic β-cells
by: Almukhtar, Hani Mhedi
Published: (2015)
by: Almukhtar, Hani Mhedi
Published: (2015)
Vitamin D3-associated lyotropic liquid crystalline nanoparticles for gemcitabine and thymoquinone delivery for treatment of luminal breast cancer with resistant characteristics
by: Loo, Yan Shan
Published: (2023)
by: Loo, Yan Shan
Published: (2023)
Combination of metformin and fec (5-fluorouracil, epirubicin, cyclophophasmide) chemotherapy as a potential therapy for targeting cancer stem cells in breast cancer / Soo Sian Siu
by: Soo , Sian Siu
Published: (2015)
by: Soo , Sian Siu
Published: (2015)
Novel derivative of aminobenzenesulfonamide (3c) induces apoptosis in colorectal cancer cells through
ROS generation and inhibits cell migration
by: Al-Khayal, Khayal A., et al.
Published: (2017)
by: Al-Khayal, Khayal A., et al.
Published: (2017)
Evaluation of antiproliferative activity of chalcone and dihydrochalcone extract from artocarpus lowii leaves on breast cancer cell lines
by: Mahmud, Norliana
Published: (2013)
by: Mahmud, Norliana
Published: (2013)
Formulation and optimization of nanoemulsion containing gemcitabine for lung cancer treatment
by: Wahgiman, Nadiatul Atiqah
Published: (2019)
by: Wahgiman, Nadiatul Atiqah
Published: (2019)
Influence of artocarpus altilis fruit extract on cancer cell
by: Ganeson, Suhassni, et al.
Published: (2019)
by: Ganeson, Suhassni, et al.
Published: (2019)
Phytocompounds of Anonna muricata leaves extract and cytotoxic effects
on breast cancer cells
by: Rahman, Husna Syakirah Ab, et al.
Published: (2018)
by: Rahman, Husna Syakirah Ab, et al.
Published: (2018)
Similar Items
-
Emerging role of the KRAS-PDK1 axis in pancreatic cancer
by: Ferro, R., et al.
Published: (2014) -
Surgical Management in Patients With Pancreatic Cancer: a Queensland Perspective
by: Wylie, N., et al.
Published: (2013) -
Cytotoxicity of SRJ23 and its derivatives, expression and SRJ23 binding of KRas G12V oncoprotein
by: Tan, Michelle Siying
Published: (2017) -
Mesoporous silica nanoparticles as anticancer drug carriers in pancreatic cancer treatment
by: Chung, Shei Li
Published: (2025) -
LY2495655, an antimyostatin antibody in pancreatic cancer: a randomized phase 2 trial
by: Golan, Talia, et al.
Published: (2018)