Performance of Azolla pinnata fern protein hydrolysates as an emulsifier and nutraceutical ingredient in an O/W emulsion system and their effect on human gut microbiota and mammalian cells

This study investigated the dual potential of Azolla pinnata fern protein hydrolysates (AFPHs) as functional and nutraceutical ingredients in an oil/water emulsion system. The AFPH-stabilised emulsion (AFPH-E) displayed a small and uniform droplet distribution and was stable to aggregation and cream...

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Main Authors: Qoms, Mohammed S., Arulrajah, Brisha, Wan Ibadullah, Wan Zunairah, Ramli, Nurul Shazini, Chau, De-Ming, Sarbini, Shahrul Razid, Saari, Nazamid
Format: Article
Published: Royal Society of Chemistry 2024
Online Access:http://psasir.upm.edu.my/id/eprint/116073/
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author Qoms, Mohammed S.
Arulrajah, Brisha
Wan Ibadullah, Wan Zunairah
Ramli, Nurul Shazini
Chau, De-Ming
Sarbini, Shahrul Razid
Saari, Nazamid
author_facet Qoms, Mohammed S.
Arulrajah, Brisha
Wan Ibadullah, Wan Zunairah
Ramli, Nurul Shazini
Chau, De-Ming
Sarbini, Shahrul Razid
Saari, Nazamid
author_sort Qoms, Mohammed S.
building UPM Institutional Repository
collection Online Access
description This study investigated the dual potential of Azolla pinnata fern protein hydrolysates (AFPHs) as functional and nutraceutical ingredients in an oil/water emulsion system. The AFPH-stabilised emulsion (AFPH-E) displayed a small and uniform droplet distribution and was stable to aggregation and creaming over a wide range of pH (5-8), salt concentrations ≤ 100 mM, and heat treatment ≤ 70 °C. Besides, the AFPH-E possessed and maintained strong biological activities, including antihypertensive, antidiabetic, and antioxidant, under different food processing conditions (pH 5-8; NaCl: 50-150 mM, and heat treatment: 30-100 °C). Following in vitro gastrointestinal digestion, the antihypertensive and antioxidant activities were unchanged, while a notable increase of 8% was observed for DPPH. However, the antidiabetic activities were partially reduced in the range of 5-11%. Notably, AFPH-E modulated the gut microbiota and short-chain fatty acids (SCFAs), promoting the growth of beneficial bacteria, particularly Bifidobacteria and Lactobacilli, along with increased SCFA acetate, propionate, and butyrate. Also, AFPH-E up to 10 mg mL−1 did not affect the proliferation of the normal colon cells. In the current work, AFPH demonstrated dual functionality as a plant-based emulsifier with strong biological activities in an oil/water emulsion system and promoted healthy changes in the human gut microbiota.
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institution Universiti Putra Malaysia
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spelling upm-1160732025-04-21T03:08:08Z http://psasir.upm.edu.my/id/eprint/116073/ Performance of Azolla pinnata fern protein hydrolysates as an emulsifier and nutraceutical ingredient in an O/W emulsion system and their effect on human gut microbiota and mammalian cells Qoms, Mohammed S. Arulrajah, Brisha Wan Ibadullah, Wan Zunairah Ramli, Nurul Shazini Chau, De-Ming Sarbini, Shahrul Razid Saari, Nazamid This study investigated the dual potential of Azolla pinnata fern protein hydrolysates (AFPHs) as functional and nutraceutical ingredients in an oil/water emulsion system. The AFPH-stabilised emulsion (AFPH-E) displayed a small and uniform droplet distribution and was stable to aggregation and creaming over a wide range of pH (5-8), salt concentrations ≤ 100 mM, and heat treatment ≤ 70 °C. Besides, the AFPH-E possessed and maintained strong biological activities, including antihypertensive, antidiabetic, and antioxidant, under different food processing conditions (pH 5-8; NaCl: 50-150 mM, and heat treatment: 30-100 °C). Following in vitro gastrointestinal digestion, the antihypertensive and antioxidant activities were unchanged, while a notable increase of 8% was observed for DPPH. However, the antidiabetic activities were partially reduced in the range of 5-11%. Notably, AFPH-E modulated the gut microbiota and short-chain fatty acids (SCFAs), promoting the growth of beneficial bacteria, particularly Bifidobacteria and Lactobacilli, along with increased SCFA acetate, propionate, and butyrate. Also, AFPH-E up to 10 mg mL−1 did not affect the proliferation of the normal colon cells. In the current work, AFPH demonstrated dual functionality as a plant-based emulsifier with strong biological activities in an oil/water emulsion system and promoted healthy changes in the human gut microbiota. Royal Society of Chemistry 2024-05-27 Article PeerReviewed Qoms, Mohammed S. and Arulrajah, Brisha and Wan Ibadullah, Wan Zunairah and Ramli, Nurul Shazini and Chau, De-Ming and Sarbini, Shahrul Razid and Saari, Nazamid (2024) Performance of Azolla pinnata fern protein hydrolysates as an emulsifier and nutraceutical ingredient in an O/W emulsion system and their effect on human gut microbiota and mammalian cells. Food and Function, 15 (12). pp. 6578-6596. ISSN 2042-6496; eISSN: 2042-650X https://pubs.rsc.org/en/content/articlelanding/2024/fo/d4fo00377b 10.1039/d4fo00377b
spellingShingle Qoms, Mohammed S.
Arulrajah, Brisha
Wan Ibadullah, Wan Zunairah
Ramli, Nurul Shazini
Chau, De-Ming
Sarbini, Shahrul Razid
Saari, Nazamid
Performance of Azolla pinnata fern protein hydrolysates as an emulsifier and nutraceutical ingredient in an O/W emulsion system and their effect on human gut microbiota and mammalian cells
title Performance of Azolla pinnata fern protein hydrolysates as an emulsifier and nutraceutical ingredient in an O/W emulsion system and their effect on human gut microbiota and mammalian cells
title_full Performance of Azolla pinnata fern protein hydrolysates as an emulsifier and nutraceutical ingredient in an O/W emulsion system and their effect on human gut microbiota and mammalian cells
title_fullStr Performance of Azolla pinnata fern protein hydrolysates as an emulsifier and nutraceutical ingredient in an O/W emulsion system and their effect on human gut microbiota and mammalian cells
title_full_unstemmed Performance of Azolla pinnata fern protein hydrolysates as an emulsifier and nutraceutical ingredient in an O/W emulsion system and their effect on human gut microbiota and mammalian cells
title_short Performance of Azolla pinnata fern protein hydrolysates as an emulsifier and nutraceutical ingredient in an O/W emulsion system and their effect on human gut microbiota and mammalian cells
title_sort performance of azolla pinnata fern protein hydrolysates as an emulsifier and nutraceutical ingredient in an o/w emulsion system and their effect on human gut microbiota and mammalian cells
url http://psasir.upm.edu.my/id/eprint/116073/
http://psasir.upm.edu.my/id/eprint/116073/
http://psasir.upm.edu.my/id/eprint/116073/