Development and evaluation of selective nitroxanthone derivatives: a promising compound for targeting MCF-7 breast cancer cells

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Development and evaluation of selective nitroxanthone derivatives: a promising compound for targeting MCF-7 breast cancer cells

A series of nitroxanthone derivatives (1–6) were synthesized and evaluated for their potential efficacy against estrogen-receptor positive (MCF-7) and triple-negative breast cancer cell lines (MDA-MB-231). Cell viability assays identified compound 1 at 10 µM as the most promising candidate due to it...

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Bibliographic Details
Main Authors:	Devakrishnan, Pavithren, Mad Nasir, Nadiah, Stanslas, Johnson, M. Latif, Muhammad Alif, Ismail, Ahmad Zaidi, Baharuddin, Fatin Farhana
Format:	Article
Language:	English
Published:	Elsevier B.V. 2025
Online Access:	http://psasir.upm.edu.my/id/eprint/115898/ http://psasir.upm.edu.my/id/eprint/115898/1/115898.pdf

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