Extraction and characterization of sodium alginate from native Malaysian brown seaweed Sargassum polycystum

Malaysian seaweed, particularly Sargassum polycystum, has potential for alginate production, yet an extraction protocol for this seaweed remains lacking. This study aimed to optimize the extraction process to maximize alginate yield while characterizing the physicochemical properties of the extracte...

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Main Authors: Alallam, Batoul, Abd Kadir, Erazuliana, Dewi, Firli Rahmah Primula, Yong, Yoke Keong, Lim, Vuanghao
Format: Article
Language:English
Published: Elsevier 2025
Online Access:http://psasir.upm.edu.my/id/eprint/115886/
http://psasir.upm.edu.my/id/eprint/115886/1/115886.pdf
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author Alallam, Batoul
Abd Kadir, Erazuliana
Dewi, Firli Rahmah Primula
Yong, Yoke Keong
Lim, Vuanghao
author_facet Alallam, Batoul
Abd Kadir, Erazuliana
Dewi, Firli Rahmah Primula
Yong, Yoke Keong
Lim, Vuanghao
author_sort Alallam, Batoul
building UPM Institutional Repository
collection Online Access
description Malaysian seaweed, particularly Sargassum polycystum, has potential for alginate production, yet an extraction protocol for this seaweed remains lacking. This study aimed to optimize the extraction process to maximize alginate yield while characterizing the physicochemical properties of the extracted alginate and its potential applications. An alkali-based extraction method was employed, with key parameters, including alkali concentration, extraction temperature, and time, carefully optimized to yield 30.17 ± 0.76 % (g alginate/100 g dry seaweed biomass) of alginate. Sodium alginate extracted from Sargassum polycystum has a viscosity-average molecular weight of 4.73 ± 0.001 × 104 g/mol and an M/G ratio of 2.87. The physicochemical properties and biochemical composition of the extracted alginate revealed its capacity to be utilized as a natural antioxidant. An alginate-based nanohybrid for polyphenol delivery was developed to explore the potential applications of extracted alginate. This nanohybrid showed favorable properties (hydrodynamic particle size: 415 nm, PDI: 0.3, zeta potential: –44.7 mV), high encapsulation (80.13 %), and loading efficiency (19.21 ± 1.69 %). Alginate coating on the nanohybrid protected polyphenol from premature release, significantly enhancing its antioxidant activity. These findings suggest that alginate extracted from Malaysian Sargassum polycystum could be a valuable natural material for developing controlled-release delivery systems.
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spelling upm-1158862025-03-14T01:11:54Z http://psasir.upm.edu.my/id/eprint/115886/ Extraction and characterization of sodium alginate from native Malaysian brown seaweed Sargassum polycystum Alallam, Batoul Abd Kadir, Erazuliana Dewi, Firli Rahmah Primula Yong, Yoke Keong Lim, Vuanghao Malaysian seaweed, particularly Sargassum polycystum, has potential for alginate production, yet an extraction protocol for this seaweed remains lacking. This study aimed to optimize the extraction process to maximize alginate yield while characterizing the physicochemical properties of the extracted alginate and its potential applications. An alkali-based extraction method was employed, with key parameters, including alkali concentration, extraction temperature, and time, carefully optimized to yield 30.17 ± 0.76 % (g alginate/100 g dry seaweed biomass) of alginate. Sodium alginate extracted from Sargassum polycystum has a viscosity-average molecular weight of 4.73 ± 0.001 × 104 g/mol and an M/G ratio of 2.87. The physicochemical properties and biochemical composition of the extracted alginate revealed its capacity to be utilized as a natural antioxidant. An alginate-based nanohybrid for polyphenol delivery was developed to explore the potential applications of extracted alginate. This nanohybrid showed favorable properties (hydrodynamic particle size: 415 nm, PDI: 0.3, zeta potential: –44.7 mV), high encapsulation (80.13 %), and loading efficiency (19.21 ± 1.69 %). Alginate coating on the nanohybrid protected polyphenol from premature release, significantly enhancing its antioxidant activity. These findings suggest that alginate extracted from Malaysian Sargassum polycystum could be a valuable natural material for developing controlled-release delivery systems. Elsevier 2025 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/115886/1/115886.pdf Alallam, Batoul and Abd Kadir, Erazuliana and Dewi, Firli Rahmah Primula and Yong, Yoke Keong and Lim, Vuanghao (2025) Extraction and characterization of sodium alginate from native Malaysian brown seaweed Sargassum polycystum. International Journal of Biological Macromolecules, 287. art. no. 138552. pp. 1-21. ISSN 0141-8130; eISSN: 1879-0003 (In Press) https://linkinghub.elsevier.com/retrieve/pii/S0141813024093632 10.1016/j.ijbiomac.2024.138552
spellingShingle Alallam, Batoul
Abd Kadir, Erazuliana
Dewi, Firli Rahmah Primula
Yong, Yoke Keong
Lim, Vuanghao
Extraction and characterization of sodium alginate from native Malaysian brown seaweed Sargassum polycystum
title Extraction and characterization of sodium alginate from native Malaysian brown seaweed Sargassum polycystum
title_full Extraction and characterization of sodium alginate from native Malaysian brown seaweed Sargassum polycystum
title_fullStr Extraction and characterization of sodium alginate from native Malaysian brown seaweed Sargassum polycystum
title_full_unstemmed Extraction and characterization of sodium alginate from native Malaysian brown seaweed Sargassum polycystum
title_short Extraction and characterization of sodium alginate from native Malaysian brown seaweed Sargassum polycystum
title_sort extraction and characterization of sodium alginate from native malaysian brown seaweed sargassum polycystum
url http://psasir.upm.edu.my/id/eprint/115886/
http://psasir.upm.edu.my/id/eprint/115886/
http://psasir.upm.edu.my/id/eprint/115886/
http://psasir.upm.edu.my/id/eprint/115886/1/115886.pdf