Global prevalence of congenital heart diseases in infants: a systematic review and meta-analysis
Background: Congenital heart anomalies, among the most common congenital abnormalities, are the leading cause of mortality resulting from congenital diseases. This study's objective is to investigate the prevalence of congenital heart diseases in infants through a systematic review and meta-ana...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024
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| Online Access: | http://psasir.upm.edu.my/id/eprint/115647/ http://psasir.upm.edu.my/id/eprint/115647/1/115647.pdf |
| _version_ | 1848866833644388352 |
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| author | Salari, Nader Faryadras, Fateme Shohaimi, Shamarina Jalili, Faramarz Hasheminezhad, Razie Babajani, Fateme Mohammadi, Masoud |
| author_facet | Salari, Nader Faryadras, Fateme Shohaimi, Shamarina Jalili, Faramarz Hasheminezhad, Razie Babajani, Fateme Mohammadi, Masoud |
| author_sort | Salari, Nader |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Background: Congenital heart anomalies, among the most common congenital abnormalities, are the leading cause of mortality resulting from congenital diseases. This study's objective is to investigate the prevalence of congenital heart diseases in infants through a systematic review and meta-analysis. Methods: This study systematically searched electronic databases, including PubMed, Scopus, Science Direct, and Web of Science, for studies reporting the global prevalence of congenital heart diseases in infants up to March 2023. Results: In the review of 16 studies with a total sample size of 35,281,800 individuals, the heterogeneity test (I2) indicated high heterogeneity (I2 = 99.8%), and a random-effects model was used to analyze the results. Accordingly, the global prevalence of congenital heart anomalies in infancy was reported to be 0.003 (95% CI: 0.002–0.004) or more precisely with exact decimals 0.0027 (95% CI: 0.0022–0.0035), which is 0.27 percent, 2.78 per 1000 and 27.8 per 10,000 births. Additionally, the assessment of publication bias in the studies, considering the large sample size, was performed using the Begg and Mazumdar correlation test, which showed no significant publication bias (p = 0.566). Conclusion: Based on the results of this study, it was reported that the global prevalence of congenital heart diseases in infants is increasing annually. Ventricular and atrial septal defects had the highest prevalence, with a higher occurrence in male infants compared to female infants. It is necessary to implement policies to reduce the prevalence of these diseases and prevent infant mortality caused by them. |
| first_indexed | 2025-11-15T14:26:53Z |
| format | Article |
| id | upm-115647 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T14:26:53Z |
| publishDate | 2024 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1156472025-04-21T02:57:37Z http://psasir.upm.edu.my/id/eprint/115647/ Global prevalence of congenital heart diseases in infants: a systematic review and meta-analysis Salari, Nader Faryadras, Fateme Shohaimi, Shamarina Jalili, Faramarz Hasheminezhad, Razie Babajani, Fateme Mohammadi, Masoud Background: Congenital heart anomalies, among the most common congenital abnormalities, are the leading cause of mortality resulting from congenital diseases. This study's objective is to investigate the prevalence of congenital heart diseases in infants through a systematic review and meta-analysis. Methods: This study systematically searched electronic databases, including PubMed, Scopus, Science Direct, and Web of Science, for studies reporting the global prevalence of congenital heart diseases in infants up to March 2023. Results: In the review of 16 studies with a total sample size of 35,281,800 individuals, the heterogeneity test (I2) indicated high heterogeneity (I2 = 99.8%), and a random-effects model was used to analyze the results. Accordingly, the global prevalence of congenital heart anomalies in infancy was reported to be 0.003 (95% CI: 0.002–0.004) or more precisely with exact decimals 0.0027 (95% CI: 0.0022–0.0035), which is 0.27 percent, 2.78 per 1000 and 27.8 per 10,000 births. Additionally, the assessment of publication bias in the studies, considering the large sample size, was performed using the Begg and Mazumdar correlation test, which showed no significant publication bias (p = 0.566). Conclusion: Based on the results of this study, it was reported that the global prevalence of congenital heart diseases in infants is increasing annually. Ventricular and atrial septal defects had the highest prevalence, with a higher occurrence in male infants compared to female infants. It is necessary to implement policies to reduce the prevalence of these diseases and prevent infant mortality caused by them. Elsevier 2024-12 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/115647/1/115647.pdf Salari, Nader and Faryadras, Fateme and Shohaimi, Shamarina and Jalili, Faramarz and Hasheminezhad, Razie and Babajani, Fateme and Mohammadi, Masoud (2024) Global prevalence of congenital heart diseases in infants: a systematic review and meta-analysis. Journal of Neonatal Nursing, 30 (6). pp. 570-575. ISSN 1355-1841; eISSN: 1878-089X https://www.sciencedirect.com/science/article/pii/S1355184124001091?via%3Dihub 10.1016/j.jnn.2024.05.003 |
| spellingShingle | Salari, Nader Faryadras, Fateme Shohaimi, Shamarina Jalili, Faramarz Hasheminezhad, Razie Babajani, Fateme Mohammadi, Masoud Global prevalence of congenital heart diseases in infants: a systematic review and meta-analysis |
| title | Global prevalence of congenital heart diseases in infants: a systematic review and meta-analysis |
| title_full | Global prevalence of congenital heart diseases in infants: a systematic review and meta-analysis |
| title_fullStr | Global prevalence of congenital heart diseases in infants: a systematic review and meta-analysis |
| title_full_unstemmed | Global prevalence of congenital heart diseases in infants: a systematic review and meta-analysis |
| title_short | Global prevalence of congenital heart diseases in infants: a systematic review and meta-analysis |
| title_sort | global prevalence of congenital heart diseases in infants: a systematic review and meta-analysis |
| url | http://psasir.upm.edu.my/id/eprint/115647/ http://psasir.upm.edu.my/id/eprint/115647/ http://psasir.upm.edu.my/id/eprint/115647/ http://psasir.upm.edu.my/id/eprint/115647/1/115647.pdf |