Idiopathic gestational gigantomastia: a case report
Background: Gestational gigantomastia (GGM) is described as a diffuse and rapid enlargement of the breasts during pregnancy. It is a rare condition with an incidence of 1 in 28,000 to 1 in 100,000 pregnancies worldwide. Case presentation: We present a case of a 29-year-old lady, G2P1 at 15 weeks ge...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Royal Thai College of Obstetricians and Gynaecologists
2025
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| Online Access: | http://psasir.upm.edu.my/id/eprint/115472/ http://psasir.upm.edu.my/id/eprint/115472/1/115472.pdf |
| _version_ | 1848866785842954240 |
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| author | Basri, Nurul Iftida Mohd Tamrin, Mohd Islahuddin Zulkifli, Nur Adila Loke, Xi-Mun |
| author_facet | Basri, Nurul Iftida Mohd Tamrin, Mohd Islahuddin Zulkifli, Nur Adila Loke, Xi-Mun |
| author_sort | Basri, Nurul Iftida |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Background: Gestational gigantomastia (GGM) is described as a diffuse and rapid enlargement of the breasts during pregnancy. It is a rare condition with an incidence of 1 in 28,000 to 1 in 100,000 pregnancies worldwide.
Case presentation: We present a case of a 29-year-old lady, G2P1 at 15 weeks gestation who presented with 2-months history of painful bilateral breast swelling. Clinical examination revealed erythematous bilateral breast enlargement. Results of multiple breast biopsies range from lactational adenoma and acute on chronic mastitis changes. She was treated with multiple courses of antibiotics for bilateral cellulitis with mastitis, however both breasts continued to enlarge. The revised diagnosis of gestational gigantomastia was made and she was started on steroid. Nevertheless, she failed to respond. Oral Bromocriptine commenced at 29 weeks showing some reduction in her breasts size. The fetus was however found to have a growth restriction requiring delivery at 37 weeks. Her breast has reduced by half of the initial volume during postnatal review. She was offered bilateral reductive mammoplasty and mastopexy, but she was not keen and opted for conservative management.
Conclusion: A thorough investigation is necessary to rule out other causes in women presenting with gigantomastia in pregnancy. GGM treatment ranges from conservative, hormonal therapy, reduction mammoplasty, mastectomy with or without reconstruction. This depends largely on the severity of disease and the patient’s wish. |
| first_indexed | 2025-11-15T14:26:08Z |
| format | Article |
| id | upm-115472 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T14:26:08Z |
| publishDate | 2025 |
| publisher | Royal Thai College of Obstetricians and Gynaecologists |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1154722025-03-04T08:30:36Z http://psasir.upm.edu.my/id/eprint/115472/ Idiopathic gestational gigantomastia: a case report Basri, Nurul Iftida Mohd Tamrin, Mohd Islahuddin Zulkifli, Nur Adila Loke, Xi-Mun Background: Gestational gigantomastia (GGM) is described as a diffuse and rapid enlargement of the breasts during pregnancy. It is a rare condition with an incidence of 1 in 28,000 to 1 in 100,000 pregnancies worldwide. Case presentation: We present a case of a 29-year-old lady, G2P1 at 15 weeks gestation who presented with 2-months history of painful bilateral breast swelling. Clinical examination revealed erythematous bilateral breast enlargement. Results of multiple breast biopsies range from lactational adenoma and acute on chronic mastitis changes. She was treated with multiple courses of antibiotics for bilateral cellulitis with mastitis, however both breasts continued to enlarge. The revised diagnosis of gestational gigantomastia was made and she was started on steroid. Nevertheless, she failed to respond. Oral Bromocriptine commenced at 29 weeks showing some reduction in her breasts size. The fetus was however found to have a growth restriction requiring delivery at 37 weeks. Her breast has reduced by half of the initial volume during postnatal review. She was offered bilateral reductive mammoplasty and mastopexy, but she was not keen and opted for conservative management. Conclusion: A thorough investigation is necessary to rule out other causes in women presenting with gigantomastia in pregnancy. GGM treatment ranges from conservative, hormonal therapy, reduction mammoplasty, mastectomy with or without reconstruction. This depends largely on the severity of disease and the patient’s wish. Royal Thai College of Obstetricians and Gynaecologists 2025 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/115472/1/115472.pdf Basri, Nurul Iftida and Mohd Tamrin, Mohd Islahuddin and Zulkifli, Nur Adila and Loke, Xi-Mun (2025) Idiopathic gestational gigantomastia: a case report. Thai Journal of Obstetrics and Gynaecology, 33 (1). pp. 77-81. ISSN 0857-6084; eISSN: 2673-0871 https://doi.nrct.go.th/?page=resolve_doi&resolve_doi=10.14456/tjog.2025.8 10.14456/tjog.2025.8 |
| spellingShingle | Basri, Nurul Iftida Mohd Tamrin, Mohd Islahuddin Zulkifli, Nur Adila Loke, Xi-Mun Idiopathic gestational gigantomastia: a case report |
| title | Idiopathic gestational gigantomastia: a case report |
| title_full | Idiopathic gestational gigantomastia: a case report |
| title_fullStr | Idiopathic gestational gigantomastia: a case report |
| title_full_unstemmed | Idiopathic gestational gigantomastia: a case report |
| title_short | Idiopathic gestational gigantomastia: a case report |
| title_sort | idiopathic gestational gigantomastia: a case report |
| url | http://psasir.upm.edu.my/id/eprint/115472/ http://psasir.upm.edu.my/id/eprint/115472/ http://psasir.upm.edu.my/id/eprint/115472/ http://psasir.upm.edu.my/id/eprint/115472/1/115472.pdf |