Impact of diabetes mellitus on osteoarthritis: a scoping review on biomarkers

Osteoarthritis (OA) commonly affects the knee and hip joints and accounts for 19.3% of disability-adjusted life years and years lived with disability worldwide (Refs 1, 2). Early management is important in order to avoid disability uphold quality of life (Ref. 3). However, a lack of awareness of sub...

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Main Authors: Seow, Shi Rui, Mat, Sumaiyah, Ahmad Azam, Amalina, Rajab, Nor Fadilah, Safinar Ismail, Intan, Singh, Devinder Kaur Ajit, Shahar, Suzana, Tan, Maw Pin, Berenbaum, Francis
Format: Article
Language:English
Published: Cambridge University Press 2024
Online Access:http://psasir.upm.edu.my/id/eprint/115294/
http://psasir.upm.edu.my/id/eprint/115294/1/115294.pdf
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author Seow, Shi Rui
Mat, Sumaiyah
Ahmad Azam, Amalina
Rajab, Nor Fadilah
Safinar Ismail, Intan
Singh, Devinder Kaur Ajit
Shahar, Suzana
Tan, Maw Pin
Berenbaum, Francis
author_facet Seow, Shi Rui
Mat, Sumaiyah
Ahmad Azam, Amalina
Rajab, Nor Fadilah
Safinar Ismail, Intan
Singh, Devinder Kaur Ajit
Shahar, Suzana
Tan, Maw Pin
Berenbaum, Francis
author_sort Seow, Shi Rui
building UPM Institutional Repository
collection Online Access
description Osteoarthritis (OA) commonly affects the knee and hip joints and accounts for 19.3% of disability-adjusted life years and years lived with disability worldwide (Refs 1, 2). Early management is important in order to avoid disability uphold quality of life (Ref. 3). However, a lack of awareness of subclinical and early symptomatic stages of OA often hampers early management (Ref. 4). Moreover, late diagnosis of OA among those with severe disease, at a stage when OA management becomes more complicated is common (Refs 5, 6, 7, 8). Established risk factors for the development and progression of OA include increasing age, female, history of trauma and obesity (Ref. 9). Recent studies have also drawn a link between OA and metabolic syndrome, which is characterized by insulin resistance, dyslipidaemia and hypertension (Refs 10, 11).
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publisher Cambridge University Press
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spelling upm-1152942025-02-28T02:06:43Z http://psasir.upm.edu.my/id/eprint/115294/ Impact of diabetes mellitus on osteoarthritis: a scoping review on biomarkers Seow, Shi Rui Mat, Sumaiyah Ahmad Azam, Amalina Rajab, Nor Fadilah Safinar Ismail, Intan Singh, Devinder Kaur Ajit Shahar, Suzana Tan, Maw Pin Berenbaum, Francis Osteoarthritis (OA) commonly affects the knee and hip joints and accounts for 19.3% of disability-adjusted life years and years lived with disability worldwide (Refs 1, 2). Early management is important in order to avoid disability uphold quality of life (Ref. 3). However, a lack of awareness of subclinical and early symptomatic stages of OA often hampers early management (Ref. 4). Moreover, late diagnosis of OA among those with severe disease, at a stage when OA management becomes more complicated is common (Refs 5, 6, 7, 8). Established risk factors for the development and progression of OA include increasing age, female, history of trauma and obesity (Ref. 9). Recent studies have also drawn a link between OA and metabolic syndrome, which is characterized by insulin resistance, dyslipidaemia and hypertension (Refs 10, 11). Cambridge University Press 2024-04-12 Article PeerReviewed text en cc_by_4 http://psasir.upm.edu.my/id/eprint/115294/1/115294.pdf Seow, Shi Rui and Mat, Sumaiyah and Ahmad Azam, Amalina and Rajab, Nor Fadilah and Safinar Ismail, Intan and Singh, Devinder Kaur Ajit and Shahar, Suzana and Tan, Maw Pin and Berenbaum, Francis (2024) Impact of diabetes mellitus on osteoarthritis: a scoping review on biomarkers. Expert Reviews in Molecular Medicine, 26. art. no. e8. pp. 1-11. ISSN 1462-3994; eISSN: 1462-3994 https://www.cambridge.org/core/journals/expert-reviews-in-molecular-medicine/article/impact-of-diabetes-mellitus-on-osteoarthritis-a-scoping-review-on-biomarkers/21A3145BE83A55AEBC1913944A29BD27 10.1017/erm.2024.7
spellingShingle Seow, Shi Rui
Mat, Sumaiyah
Ahmad Azam, Amalina
Rajab, Nor Fadilah
Safinar Ismail, Intan
Singh, Devinder Kaur Ajit
Shahar, Suzana
Tan, Maw Pin
Berenbaum, Francis
Impact of diabetes mellitus on osteoarthritis: a scoping review on biomarkers
title Impact of diabetes mellitus on osteoarthritis: a scoping review on biomarkers
title_full Impact of diabetes mellitus on osteoarthritis: a scoping review on biomarkers
title_fullStr Impact of diabetes mellitus on osteoarthritis: a scoping review on biomarkers
title_full_unstemmed Impact of diabetes mellitus on osteoarthritis: a scoping review on biomarkers
title_short Impact of diabetes mellitus on osteoarthritis: a scoping review on biomarkers
title_sort impact of diabetes mellitus on osteoarthritis: a scoping review on biomarkers
url http://psasir.upm.edu.my/id/eprint/115294/
http://psasir.upm.edu.my/id/eprint/115294/
http://psasir.upm.edu.my/id/eprint/115294/
http://psasir.upm.edu.my/id/eprint/115294/1/115294.pdf