Aspartame precursor synthesis in water miscible cosolvent catalysed by thermolysin

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Aspartame precursor synthesis in water miscible cosolvent catalysed by thermolysin

The synthesis of the dipeptide N-benzyloxycarbonyl-L- aspartyl-phenylalanine methyl ester, aspartame precursor, catalysed by thermolysin in aqueous and aqueous methanolic solutions was studied. Thermolysin with concentration as low as 10 μM in 25% methanol can catalyse the synthetic reaction. The op...

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Bibliographic Details
Main Authors:	Lee, Kong H., Lee, Pat M., Siaw, Y.S., Morihara, Kazuyuki
Format:	Article
Language:	English
Published:	Springer Science and Business Media LLC 1992
Online Access:	http://psasir.upm.edu.my/id/eprint/115092/ http://psasir.upm.edu.my/id/eprint/115092/1/115092.pdf

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