Insulinotropic activity of Tinospora crispa extract: effect on β-cell Ca2+ handling

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Insulinotropic activity of Tinospora crispa extract: effect on β-cell Ca2+ handling

The mechanism of insulinotropic action of Tinospora crispa was investigated in vitro using an insulin-secreting clonal β-cell line, HIT-T15. The aqueous extract sensitizes the β-cell to extracellular Ca2+ and promotes intracellular Ca2+ accumulation which in turn causes increased insulin release. Th...

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Bibliographic Details
Main Authors:	Noor, Hamdan, Ashcroft, Stephen J. H.
Format:	Article
Language:	English
Published:	Wiley 1998
Online Access:	http://psasir.upm.edu.my/id/eprint/115037/ http://psasir.upm.edu.my/id/eprint/115037/1/115037.pdf

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