Effects of methanol on the synthesis of aspartame precursor catalysed by Pseudomonas aeruginosa elastase

Pseudomonas elastase was found to be efficient in catalysing the reaction between N-benzyloxycarbonyl-L-aspartic acid and L-phenylalanine methyl ester producing the aspartame precursor in aqueous and aqueous methanolic solutions. 25% (v/v) methanol was most favourable for the synthesis where about 1...

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Main Authors: Lee, K.H., Lee, P.M., Siaw, Y.S., Morihara, K.
Format: Article
Language:English
Published: Kluwer Academic Publishers 1992
Online Access:http://psasir.upm.edu.my/id/eprint/114968/
http://psasir.upm.edu.my/id/eprint/114968/1/114968.pdf
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author Lee, K.H.
Lee, P.M.
Siaw, Y.S.
Morihara, K.
author_facet Lee, K.H.
Lee, P.M.
Siaw, Y.S.
Morihara, K.
author_sort Lee, K.H.
building UPM Institutional Repository
collection Online Access
description Pseudomonas elastase was found to be efficient in catalysing the reaction between N-benzyloxycarbonyl-L-aspartic acid and L-phenylalanine methyl ester producing the aspartame precursor in aqueous and aqueous methanolic solutions. 25% (v/v) methanol was most favourable for the synthesis where about 100% increase in yield was obtained compared to that in aqueous solution.
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institution Universiti Putra Malaysia
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publishDate 1992
publisher Kluwer Academic Publishers
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spelling upm-1149682025-02-13T03:17:08Z http://psasir.upm.edu.my/id/eprint/114968/ Effects of methanol on the synthesis of aspartame precursor catalysed by Pseudomonas aeruginosa elastase Lee, K.H. Lee, P.M. Siaw, Y.S. Morihara, K. Pseudomonas elastase was found to be efficient in catalysing the reaction between N-benzyloxycarbonyl-L-aspartic acid and L-phenylalanine methyl ester producing the aspartame precursor in aqueous and aqueous methanolic solutions. 25% (v/v) methanol was most favourable for the synthesis where about 100% increase in yield was obtained compared to that in aqueous solution. Kluwer Academic Publishers 1992-09 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/114968/1/114968.pdf Lee, K.H. and Lee, P.M. and Siaw, Y.S. and Morihara, K. (1992) Effects of methanol on the synthesis of aspartame precursor catalysed by Pseudomonas aeruginosa elastase. Biotechnology Letters, 14 (9). pp. 779-784. ISSN 0141-5492; eISSN: 1573-6776 https://link.springer.com/article/10.1007/BF01029138?error=cookies_not_supported&code=1f5bf1d8-f520-4c30-8170-793810bdceb4 10.1007/BF01029138
spellingShingle Lee, K.H.
Lee, P.M.
Siaw, Y.S.
Morihara, K.
Effects of methanol on the synthesis of aspartame precursor catalysed by Pseudomonas aeruginosa elastase
title Effects of methanol on the synthesis of aspartame precursor catalysed by Pseudomonas aeruginosa elastase
title_full Effects of methanol on the synthesis of aspartame precursor catalysed by Pseudomonas aeruginosa elastase
title_fullStr Effects of methanol on the synthesis of aspartame precursor catalysed by Pseudomonas aeruginosa elastase
title_full_unstemmed Effects of methanol on the synthesis of aspartame precursor catalysed by Pseudomonas aeruginosa elastase
title_short Effects of methanol on the synthesis of aspartame precursor catalysed by Pseudomonas aeruginosa elastase
title_sort effects of methanol on the synthesis of aspartame precursor catalysed by pseudomonas aeruginosa elastase
url http://psasir.upm.edu.my/id/eprint/114968/
http://psasir.upm.edu.my/id/eprint/114968/
http://psasir.upm.edu.my/id/eprint/114968/
http://psasir.upm.edu.my/id/eprint/114968/1/114968.pdf