Coordination chemistry and biological activity of two tridentate ONS and NNS Schiff bases derived from S-benzyldithiocarbazate
Two tridentate Schiff bases having ONS and NNS donor sequences were prepared by condensing S-benzyldithiocarbazate (NH2NHCSSCH2Ph) (SBDTC) with pyridine-2-carboxaldehyde and salicylaldehyde, respectively. Complexes of these ligands with NiII, ZnII, CrIII, CoII, CuII, and SnII were studied and charac...
| Main Authors: | , , , |
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| Format: | Article |
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Kluwer Academic Publishers
2000
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| Online Access: | http://psasir.upm.edu.my/id/eprint/114457/ |
| _version_ | 1848866500366041088 |
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| author | Tofazzal, M. Tarafder, H. Ali, Manaf A. Saravanan, N. |
| author_facet | Tofazzal, M. Tarafder, H. Ali, Manaf A. Saravanan, N. |
| author_sort | Tofazzal, M. |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Two tridentate Schiff bases having ONS and NNS donor sequences were prepared by condensing S-benzyldithiocarbazate (NH2NHCSSCH2Ph) (SBDTC) with pyridine-2-carboxaldehyde and salicylaldehyde, respectively. Complexes of these ligands with NiII, ZnII, CrIII, CoII, CuII, and SnII were studied and characterized by elemental analyses and various physico-chemical techniques. NiII, CuII, ZnII and SnII complexes were four-coordinate while the CrIII, SrIII and CoIII complexes were six-coordinate. The ONS Schiff base was moderately active against leukemia, while its zinc, antimony and cobalt complexes were strongly active against leukemic cells with DC50 = 0.35-5.00. |
| first_indexed | 2025-11-15T14:21:35Z |
| format | Article |
| id | upm-114457 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T14:21:35Z |
| publishDate | 2000 |
| publisher | Kluwer Academic Publishers |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1144572025-01-15T07:59:12Z http://psasir.upm.edu.my/id/eprint/114457/ Coordination chemistry and biological activity of two tridentate ONS and NNS Schiff bases derived from S-benzyldithiocarbazate Tofazzal, M. Tarafder, H. Ali, Manaf A. Saravanan, N. Two tridentate Schiff bases having ONS and NNS donor sequences were prepared by condensing S-benzyldithiocarbazate (NH2NHCSSCH2Ph) (SBDTC) with pyridine-2-carboxaldehyde and salicylaldehyde, respectively. Complexes of these ligands with NiII, ZnII, CrIII, CoII, CuII, and SnII were studied and characterized by elemental analyses and various physico-chemical techniques. NiII, CuII, ZnII and SnII complexes were four-coordinate while the CrIII, SrIII and CoIII complexes were six-coordinate. The ONS Schiff base was moderately active against leukemia, while its zinc, antimony and cobalt complexes were strongly active against leukemic cells with DC50 = 0.35-5.00. Kluwer Academic Publishers 2000 Article PeerReviewed Tofazzal, M. and Tarafder, H. and Ali, Manaf A. and Saravanan, N. (2000) Coordination chemistry and biological activity of two tridentate ONS and NNS Schiff bases derived from S-benzyldithiocarbazate. Transition Metal Chemistry, 25 (3). pp. 295-298. ISSN 0340-4285; eISSN: 0340-4285 https://link.springer.com/article/10.1023/A:1007044910814?error=cookies_not_supported&code=bc87005a-4924-4d25-be24-262a7a060f0c 10.1023/A:1007044910814 |
| spellingShingle | Tofazzal, M. Tarafder, H. Ali, Manaf A. Saravanan, N. Coordination chemistry and biological activity of two tridentate ONS and NNS Schiff bases derived from S-benzyldithiocarbazate |
| title | Coordination chemistry and biological activity of two tridentate ONS and NNS Schiff bases derived from S-benzyldithiocarbazate |
| title_full | Coordination chemistry and biological activity of two tridentate ONS and NNS Schiff bases derived from S-benzyldithiocarbazate |
| title_fullStr | Coordination chemistry and biological activity of two tridentate ONS and NNS Schiff bases derived from S-benzyldithiocarbazate |
| title_full_unstemmed | Coordination chemistry and biological activity of two tridentate ONS and NNS Schiff bases derived from S-benzyldithiocarbazate |
| title_short | Coordination chemistry and biological activity of two tridentate ONS and NNS Schiff bases derived from S-benzyldithiocarbazate |
| title_sort | coordination chemistry and biological activity of two tridentate ons and nns schiff bases derived from s-benzyldithiocarbazate |
| url | http://psasir.upm.edu.my/id/eprint/114457/ http://psasir.upm.edu.my/id/eprint/114457/ http://psasir.upm.edu.my/id/eprint/114457/ |