Inhibition of angiogenesis and metastasis in colorectal cancer cell lines through KRAS-associated signaling pathways by 2-methoxy-6-undecyl-1,4-benzoquinone

QR Code

Inhibition of angiogenesis and metastasis in colorectal cancer cell lines through KRAS-associated signaling pathways by 2-methoxy-6-undecyl-1,4-benzoquinone

Colorectal cancer (CRC), the third most prevalent cancer globally, presents formidable hurdles in treatment owing to factors such as therapeutic resistance and genetic mutations affecting primary drug targets. 2-methoxy-6-undecyl-1,4-benzoquinone (BQ), derived from Ardisia crispa roots, has emerged...

Full description

Bibliographic Details
Main Authors:	Abd Rahman, Noor Izzah, Tham, Chau Ling, Abd Hamid @ Abdul Razak, Roslida
Format:	Article
Language:	English
Published:	Elsevier Ireland 2024
Online Access:	http://psasir.upm.edu.my/id/eprint/113669/ http://psasir.upm.edu.my/id/eprint/113669/1/113669.pdf

Similar Items

Inhibition of angiogenesis and metastasis in colorectal cancer cell lines through KRAS-associated signaling pathways by 2-methoxy-6-undecyl-1,4-benzoquinone
by: Abd Rahman, Noor Izzah, et al.
Published: (2024)

Synthesis of N-methoxy-N-methylaminocarbonyl-l, 4-benzoquinone: the First Quinone Carrying an N-methoxy-N-methylamino Group
by: Ahmad, Faujan
Published: (1988)

A 1, 4-benzoquinone derivative isolated from Ardisia crispa (Thunb.) A. DC. root suppresses angiogenesis via its angiogenic signaling cascades
by: Lim, Wen Jun, et al.
Published: (2024)

Ardisia crispa roots inhibit cyclooxygenase and suppress angiogenesis
by: Awang Hamsin, Dayang Erna Zulaikha, et al.
Published: (2014)

Ardisia crispa roots inhibit cyclooxygenase and suppress angiogenesis
by: Dayang Erna Zulaikha, Awang Hamsin, et al.
Published: (2014)

Mechanisms of colorectal cancer cell growth and metastasis inhibition by Carp-1 functional mimetic-4
by: Ashour, Abdelkader Elbadawy Abbas, et al.
Published: (2019)

Mechanisms of colorectal cancer cell growth and metastasis inhibition by CARP-1 functional mimetic-4
by: Ashour, Abdelkader Elbadawy Abbas, et al.
Published: (2019)

Photocatalytic degradation of 1,4-Benzoquinone in aqueous ZnO dispersions.
by: Abdollahi, Yadollah, et al.
Published: (2012)

Photocatalytic degradaton of 1,4-Benzoquinone in aqueous ZnO suspension.
by: Abdollahi, Yadollah, et al.
Published: (2012)

Phyllanthus inhibits proliferation, metastasis, angiogenesis and induces apoptosis of human melanoma (mewo) and prostate adenocarcinoma (pc-3) cells through modulation of multiple cell signalling pathways / Tang Yin Quan
by: Tang, Yin Quan
Published: (2013)

Association between autophagy and KRAS mutation with clinicopathological variables in colorectal cancer patients
by: Awi, Noel Jacques, et al.
Published: (2021)

The Potential Anti-Tumor Extract Of Ocimum Basilicum Lamiaceae Towards Colorectal Cancer Via The Angiogenesis Mechanistic Pathway
by: Al Deeb, Ibrahim Deeb Tawfiq
Published: (2021)

Fundamental study on the effects of epha2 inhibitation in angiogenesis signaling pathways of human malignant glioma cells
by: Farizan, Ahmad
Published: (2018)

Angiogenesis inhibitors from natural sources
by: Abd Hamid, Roslida, et al.
Published: (2016)

The hexane fraction of Ardisia crispa Thunb. A. DC. roots inhibits inflammation-induced angiogenesis
by: Awang Hamsin, Dayang Erna Zulaikha, et al.
Published: (2013)

Pattern Formation by Lateral Inhibition in Physiological and Tumour Angiogenesis
by: Smith, Holly
Published: (2020)

Effects of sodium sulfate and sodium chloride for sonochemical degradation on1,4-benzoquinone and hydroquinone in aqueous solution
by: Uddin, Md. Helal, et al.
Published: (2018)

Bioactive fractions and compound of Ardisia crispa roots exhibit anti-arthritic properties mediated via angiogenesis inhibition in vitro
by: Blin, Joan, et al.
Published: (2021)

The hexane fraction of Ardisia crispa Thunb. A. DC. roots inhibits inflammation-induced angiogenesis
by: Dayang Erna Zulaikha, Awang Hamsin, et al.
Published: (2013)

Study Of Pithecellobium Jiringa (Jack) Prain On Carcinogenesis And Angiogenesis Mechanistic Pathway
by: Muslim, Nahdzatul Syima
Published: (2012)

Characterisation of deregulated micrornas in human non-small cell lung cancer and their role in tumour angiogenesis and metastasis / Ho Chai San
by: Ho , Chai San
Published: (2017)

γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model
by: Siveen, K., et al.
Published: (2014)

The effects of 2-methoxy-1,4-naphthoquinone (mnq) on glucose metabolism of mda-mb-231 cells
by: Daud, Syukriyah Mat
Published: (2020)

Luteolin, a bioflavonoid inhibits colorectal cancer through modulation of multiple signaling pathways: a review
by: Pandurangan, Ashok Kumar, et al.
Published: (2014)

Syzygium campanulatum korth methanolic extract inhibits angiogenesis and tumor growth in nude mice
by: Abdalrahim , FA Aisha, et al.
Published: (2013)

Anti-Tumor Studies Of A Selection Of Sudanese Indigenous Herbs Via The Angiogenesis Pathway
by: Hassan, Loiy Elsir Ahmed
Published: (2015)

Effect of secretion efficiency of mutant KRAS neoantigen by Lactococcus lactis on the immune response of a mucosal vaccine delivery vehicle targeting colorectal cancer
by: Alias, Nur Aqlili Riana, et al.
Published: (2023)

Formation of inclusion complex of curcumin and tetrahydrocurcumin prevents angiogenesis by inhibiting VEGF activity : an in-silico study
by: Dewi, Firli Rahmah Primula, et al.
Published: (2024)

Ethanol Extract Of Orthosiphon Stamineus Benth. Exhibits Antiobesity Effect By Inhibiting Angiogenesis And Pancreatic Lipase
by: Hashim, Suzana
Published: (2016)

Formation of inclusion complex of curcumin and tetrahydrocurcumin prevents angiogenesis by inhibiting VEGF activity: an in-silico study
by: Dewi, Firli Rahmah Primula, et al.
Published: (2024)

Emerging role of the KRAS-PDK1 axis in pancreatic cancer
by: Ferro, R., et al.
Published: (2014)

Potential ability of phytochemical in inhibition of invadopodia formation and HIF-1α in cancer metastasis
by: Hamad, Hamad Ali, et al.
Published: (2019)

Analysis of V-Ki-Ras2 Kirsten rat sarcoma viral oncogene (Kras) and differential expressed miRNA in various stages of colorectal cancer
by: Lye, Kwan Liang
Published: (2013)

CARP-1 functional mimetic-4 is a novel suppressor of colorectal cancer cell growth and metastasis
by: Ashour, Abdelkader Elbadawy Abbas
Published: (2019)

Grades of poorly differentiated clusters are associated with lymph node and the tumour, node and metastasis stages in colorectal carcinoma
by: Kerisnon@Krishnan, Thanamogan, et al.
Published: (2023)

Pericytes in Metastasis
by: Pieterse, Z., et al.
Published: (2019)

The Potential Anti-Cancer Effects Of Psidium Guajava (Guava) Leaves On Coloretal Cancer Via The Inhibition Of Angiogenesis
by: Bronwyn, Lok
Published: (2019)

Metastasis within a metastasis to the thyroid: A rare phenomenon
by: Wong, Yin PIng, et al.
Published: (2017)

Effects of CXCR4 Silencing by Sirna Engrafted Cotionized Dextran in Mouse Models of Colorectal Cancer and Liver Metastasis
by: Abedini, Fatemeh
Published: (2011)

Development of a single-chain fragment variable fused-mutant HALT-1 recombinant immunotoxin against G12V mutated KRAS colorectal cancer cells
by: Teo, Michelle Yee Mun, et al.
Published: (2021)