Effect of domain manipulation in the Staphylococcal Phage endolysin, Endo88, on lytic efficiency and host range

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Effect of domain manipulation in the Staphylococcal Phage endolysin, Endo88, on lytic efficiency and host range

The bacteriophage endolysin Endo88 targeting Staphylococcus aureus PS88 consists of the CHAP and Amidase-2 enzymatic domains and one SH3b targeting domain. In this study, the effects of domain manipulations on Endo88 functionality were determined. Three truncated mutants of Endo88 (CHAP, CHAPAmidase...

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Bibliographic Details
Main Authors:	Krishnan, Melvina, Tham, Hong Yun, Wan Nur Ismah, Wan Ahmad Kamil, Yusoff, Khatijah, Song, Adelene Ai-Lian
Format:	Article
Language:	English
Published:	Springer 2024
Online Access:	http://psasir.upm.edu.my/id/eprint/113322/ http://psasir.upm.edu.my/id/eprint/113322/1/113322.pdf

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