In vitro cytotoxicity assessment of ruxolitinib on oligodendrocyte precursor cell and neural stem/progenitor cell populations

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In vitro cytotoxicity assessment of ruxolitinib on oligodendrocyte precursor cell and neural stem/progenitor cell populations

JAK-STAT signaling cascade has emerged as an ideal target for the treatment of myeloproliferative diseases, autoimmune diseases, and neurological disorders. Ruxolitinib (Rux), is an orally bioavailable, potent and selective Janus-associated kinase (JAK) inhibitor, proven to be effective to target...

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Bibliographic Details
Main Authors:	Lim, Cheng-Wei, Hamanaka, Gen, Liang, Anna C., Chan, Su Jing, Ling, King-Hwa, Lo, Eng H., Arai, Ken, Cheah, Pike See
Format:	Article
Language:	English
Published:	Elsevier
Online Access:	http://psasir.upm.edu.my/id/eprint/113251/ http://psasir.upm.edu.my/id/eprint/113251/1/113251.pdf

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