Characterization and identification of Oya virus, a Simbu serogroup virus of the genus Bunyavirus, isolated from a pig suspected of Nipah virus infection

A virus, named Oya virus, was isolated in Vero cell cultures from the lungs of a pig suspected of Nipah virus infection. The virus was revealed as a spherical enveloped RNA virus with a diameter of 79 nm. For identification of Oya virus, RT-PCR was performed. A common primer set for S-RNA of the Sim...

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Main Authors: Kono, Y., Yusnita, Y., Mohd Ali, A. R., Maizan, M., Sharifah, S. H., Fauzia, O., Kubo, M., Aziz, A. J.
Format: Article
Published: Springer 2002
Online Access:http://psasir.upm.edu.my/id/eprint/113117/
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author Kono, Y.
Yusnita, Y.
Mohd Ali, A. R.
Maizan, M.
Sharifah, S. H.
Fauzia, O.
Kubo, M.
Aziz, A. J.
author_facet Kono, Y.
Yusnita, Y.
Mohd Ali, A. R.
Maizan, M.
Sharifah, S. H.
Fauzia, O.
Kubo, M.
Aziz, A. J.
author_sort Kono, Y.
building UPM Institutional Repository
collection Online Access
description A virus, named Oya virus, was isolated in Vero cell cultures from the lungs of a pig suspected of Nipah virus infection. The virus was revealed as a spherical enveloped RNA virus with a diameter of 79 nm. For identification of Oya virus, RT-PCR was performed. A common primer set for S-RNA of the Simbu serogroup of the genus Bunyavirus was able to amplify a cDNA from Oya virus RNA. The sequence data of the product revealed that the partial gene of Oya virus S-RNA segment had 65-70% homology with published cDNA sequences of Simbu serogroup viruses. The phylogenetic analysis of the data showed that the Oya virus is grouped in Simbu serogroup, but is genetically distinct from the serogroup viruses that have been analyzed molecularly. Serological surveys revealed that the virus distributed widely and densely in Malaysia.
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institution Universiti Putra Malaysia
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spelling upm-1131172025-01-10T03:33:42Z http://psasir.upm.edu.my/id/eprint/113117/ Characterization and identification of Oya virus, a Simbu serogroup virus of the genus Bunyavirus, isolated from a pig suspected of Nipah virus infection Kono, Y. Yusnita, Y. Mohd Ali, A. R. Maizan, M. Sharifah, S. H. Fauzia, O. Kubo, M. Aziz, A. J. A virus, named Oya virus, was isolated in Vero cell cultures from the lungs of a pig suspected of Nipah virus infection. The virus was revealed as a spherical enveloped RNA virus with a diameter of 79 nm. For identification of Oya virus, RT-PCR was performed. A common primer set for S-RNA of the Simbu serogroup of the genus Bunyavirus was able to amplify a cDNA from Oya virus RNA. The sequence data of the product revealed that the partial gene of Oya virus S-RNA segment had 65-70% homology with published cDNA sequences of Simbu serogroup viruses. The phylogenetic analysis of the data showed that the Oya virus is grouped in Simbu serogroup, but is genetically distinct from the serogroup viruses that have been analyzed molecularly. Serological surveys revealed that the virus distributed widely and densely in Malaysia. Springer 2002 Article PeerReviewed Kono, Y. and Yusnita, Y. and Mohd Ali, A. R. and Maizan, M. and Sharifah, S. H. and Fauzia, O. and Kubo, M. and Aziz, A. J. (2002) Characterization and identification of Oya virus, a Simbu serogroup virus of the genus Bunyavirus, isolated from a pig suspected of Nipah virus infection. Archives of Virology, 147 (8). pp. 1623-1630. ISSN 0304-8608; eISSN: 1432-8798 https://link.springer.com/article/10.1007/s00705-002-0838-y?error=cookies_not_supported&code=60e8f663-7d1f-4e35-9129-c9fbbee52b6b 10.1007/s00705-002-0838-y
spellingShingle Kono, Y.
Yusnita, Y.
Mohd Ali, A. R.
Maizan, M.
Sharifah, S. H.
Fauzia, O.
Kubo, M.
Aziz, A. J.
Characterization and identification of Oya virus, a Simbu serogroup virus of the genus Bunyavirus, isolated from a pig suspected of Nipah virus infection
title Characterization and identification of Oya virus, a Simbu serogroup virus of the genus Bunyavirus, isolated from a pig suspected of Nipah virus infection
title_full Characterization and identification of Oya virus, a Simbu serogroup virus of the genus Bunyavirus, isolated from a pig suspected of Nipah virus infection
title_fullStr Characterization and identification of Oya virus, a Simbu serogroup virus of the genus Bunyavirus, isolated from a pig suspected of Nipah virus infection
title_full_unstemmed Characterization and identification of Oya virus, a Simbu serogroup virus of the genus Bunyavirus, isolated from a pig suspected of Nipah virus infection
title_short Characterization and identification of Oya virus, a Simbu serogroup virus of the genus Bunyavirus, isolated from a pig suspected of Nipah virus infection
title_sort characterization and identification of oya virus, a simbu serogroup virus of the genus bunyavirus, isolated from a pig suspected of nipah virus infection
url http://psasir.upm.edu.my/id/eprint/113117/
http://psasir.upm.edu.my/id/eprint/113117/
http://psasir.upm.edu.my/id/eprint/113117/