Studies on coordination chemistry of a nitrogen–sulfur donor ligand with lighter and heavier metal ions and biological activities of its complexes
Complexes of S-benzyldithiocarbazate (SBDTC) with lighter and heavier metals, viz., CrIII, FeIII, SbIII, ZrIV, ThIV and UVI have been prepared and characterized by elemental analyses, conductivity measurements, and spectral studies. The complexes: [Cr(SBDTCA)3],** [Fe(SBDTCA)3], [Sb(SBDTCA)3], [Sb(S...
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| Format: | Article |
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Springer
2001
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| Online Access: | http://psasir.upm.edu.my/id/eprint/112963/ |
| _version_ | 1848866089787719680 |
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| author | H. Tarafder, M. Tofazzal Asmadi, A. Talib, Siti M. S. Ali, A. M. Crouse, K. A. |
| author_facet | H. Tarafder, M. Tofazzal Asmadi, A. Talib, Siti M. S. Ali, A. M. Crouse, K. A. |
| author_sort | H. Tarafder, M. Tofazzal |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Complexes of S-benzyldithiocarbazate (SBDTC) with lighter and heavier metals, viz., CrIII, FeIII, SbIII, ZrIV, ThIV and UVI have been prepared and characterized by elemental analyses, conductivity measurements, and spectral studies. The complexes: [Cr(SBDTCA)3],** [Fe(SBDTCA)3], [Sb(SBDTCA)3], [Sb(SBDTCA)2Cl · H2O], [Zr(O)(SBDTCA)2 · H2O)], [Th(SBDTCA)(NO3)3 · H2O)], and [U(O)2(SBDTCA)2] were all prepared in alkaline media. They were all hexa-coordinated with bidentate, uninegative chelation of the ligand. [Fe(SBDTCA)3], [Sb(SBDTCA)3] and [Sb(SBDTCA)2Cl · H2O] were strongly effective against bacteria giving clear inhibition zones with Pseudomonas aeruginosa and Bacillus cereus. The compounds showed poor antifungal activity. The antimony complexes were strongly cytotoxic against leukemic cells with CD50 values of 3.2-6.7 μg cm-3 as compared to the CD50 value of 14.5 μg cm-3 of the free SbCl3 molecule. |
| first_indexed | 2025-11-15T14:15:04Z |
| format | Article |
| id | upm-112963 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T14:15:04Z |
| publishDate | 2001 |
| publisher | Springer |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1129632025-01-13T02:45:43Z http://psasir.upm.edu.my/id/eprint/112963/ Studies on coordination chemistry of a nitrogen–sulfur donor ligand with lighter and heavier metal ions and biological activities of its complexes H. Tarafder, M. Tofazzal Asmadi, A. Talib, Siti M. S. Ali, A. M. Crouse, K. A. Complexes of S-benzyldithiocarbazate (SBDTC) with lighter and heavier metals, viz., CrIII, FeIII, SbIII, ZrIV, ThIV and UVI have been prepared and characterized by elemental analyses, conductivity measurements, and spectral studies. The complexes: [Cr(SBDTCA)3],** [Fe(SBDTCA)3], [Sb(SBDTCA)3], [Sb(SBDTCA)2Cl · H2O], [Zr(O)(SBDTCA)2 · H2O)], [Th(SBDTCA)(NO3)3 · H2O)], and [U(O)2(SBDTCA)2] were all prepared in alkaline media. They were all hexa-coordinated with bidentate, uninegative chelation of the ligand. [Fe(SBDTCA)3], [Sb(SBDTCA)3] and [Sb(SBDTCA)2Cl · H2O] were strongly effective against bacteria giving clear inhibition zones with Pseudomonas aeruginosa and Bacillus cereus. The compounds showed poor antifungal activity. The antimony complexes were strongly cytotoxic against leukemic cells with CD50 values of 3.2-6.7 μg cm-3 as compared to the CD50 value of 14.5 μg cm-3 of the free SbCl3 molecule. Springer 2001 Article PeerReviewed H. Tarafder, M. Tofazzal and Asmadi, A. and Talib, Siti M. S. and Ali, A. M. and Crouse, K. A. (2001) Studies on coordination chemistry of a nitrogen–sulfur donor ligand with lighter and heavier metal ions and biological activities of its complexes. Transition Metal Chemistry, 26 (1/2). pp. 170-174. ISSN 0340-4285; eISSN: 1572-901X https://link.springer.com/article/10.1023/A:1007119504397?error=cookies_not_supported&code=6288130c-75ea-4537-9cb5-e9d883a0a8cb 10.1023/a:1007119504397 |
| spellingShingle | H. Tarafder, M. Tofazzal Asmadi, A. Talib, Siti M. S. Ali, A. M. Crouse, K. A. Studies on coordination chemistry of a nitrogen–sulfur donor ligand with lighter and heavier metal ions and biological activities of its complexes |
| title | Studies on coordination chemistry of a nitrogen–sulfur donor ligand with lighter and heavier metal ions and biological activities of its complexes |
| title_full | Studies on coordination chemistry of a nitrogen–sulfur donor ligand with lighter and heavier metal ions and biological activities of its complexes |
| title_fullStr | Studies on coordination chemistry of a nitrogen–sulfur donor ligand with lighter and heavier metal ions and biological activities of its complexes |
| title_full_unstemmed | Studies on coordination chemistry of a nitrogen–sulfur donor ligand with lighter and heavier metal ions and biological activities of its complexes |
| title_short | Studies on coordination chemistry of a nitrogen–sulfur donor ligand with lighter and heavier metal ions and biological activities of its complexes |
| title_sort | studies on coordination chemistry of a nitrogen–sulfur donor ligand with lighter and heavier metal ions and biological activities of its complexes |
| url | http://psasir.upm.edu.my/id/eprint/112963/ http://psasir.upm.edu.my/id/eprint/112963/ http://psasir.upm.edu.my/id/eprint/112963/ |