Evidence Of Astrocytic Reactivity During Vestibular Compensation

Vestibular compensation is the spontaneous disappearance of postural and oculomotor imbalance exhibited by the vestibular system in response to decreased inputs from the labyrinths. Astrocytes in the vestibular nuclei have been reported to have a role in the plasticity of the central nervous syst...

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Main Author: Lee, Su Ann
Format: Thesis
Language:English
English
Published: 2003
Online Access:http://psasir.upm.edu.my/id/eprint/11247/
http://psasir.upm.edu.my/id/eprint/11247/1/FPSK_M_2003_5.pdf
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author Lee, Su Ann
author_facet Lee, Su Ann
author_sort Lee, Su Ann
building UPM Institutional Repository
collection Online Access
description Vestibular compensation is the spontaneous disappearance of postural and oculomotor imbalance exhibited by the vestibular system in response to decreased inputs from the labyrinths. Astrocytes in the vestibular nuclei have been reported to have a role in the plasticity of the central nervous system. The present study was conducted to investigate the behavioural changes of mice and the morphological changes and distribution of astrocytes following unilateral labyrinthectomy. Thirty-five mice (Mus musculus) underwent unilateral labyrinthectomy (UL) and fourteen underwent sham-operation. Their behavioural changes following surgical removal of labyrinths, or sham-operation, were observed. The UL groups displayed behavioural changes including head tilt, circular walking, barrel-rolling and extension and flexion of limbs. These behavioural symptoms disappeared within approximately 3 hours. For the sham-operated animals, these symptoms were absent.
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institution Universiti Putra Malaysia
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language English
English
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publishDate 2003
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spelling upm-112472024-06-13T01:43:11Z http://psasir.upm.edu.my/id/eprint/11247/ Evidence Of Astrocytic Reactivity During Vestibular Compensation Lee, Su Ann Vestibular compensation is the spontaneous disappearance of postural and oculomotor imbalance exhibited by the vestibular system in response to decreased inputs from the labyrinths. Astrocytes in the vestibular nuclei have been reported to have a role in the plasticity of the central nervous system. The present study was conducted to investigate the behavioural changes of mice and the morphological changes and distribution of astrocytes following unilateral labyrinthectomy. Thirty-five mice (Mus musculus) underwent unilateral labyrinthectomy (UL) and fourteen underwent sham-operation. Their behavioural changes following surgical removal of labyrinths, or sham-operation, were observed. The UL groups displayed behavioural changes including head tilt, circular walking, barrel-rolling and extension and flexion of limbs. These behavioural symptoms disappeared within approximately 3 hours. For the sham-operated animals, these symptoms were absent. 2003-07 Thesis NonPeerReviewed text en http://psasir.upm.edu.my/id/eprint/11247/1/FPSK_M_2003_5.pdf Lee, Su Ann (2003) Evidence Of Astrocytic Reactivity During Vestibular Compensation. Masters thesis, Universiti Putra Malaysia. English
spellingShingle Lee, Su Ann
Evidence Of Astrocytic Reactivity During Vestibular Compensation
title Evidence Of Astrocytic Reactivity During Vestibular Compensation
title_full Evidence Of Astrocytic Reactivity During Vestibular Compensation
title_fullStr Evidence Of Astrocytic Reactivity During Vestibular Compensation
title_full_unstemmed Evidence Of Astrocytic Reactivity During Vestibular Compensation
title_short Evidence Of Astrocytic Reactivity During Vestibular Compensation
title_sort evidence of astrocytic reactivity during vestibular compensation
url http://psasir.upm.edu.my/id/eprint/11247/
http://psasir.upm.edu.my/id/eprint/11247/1/FPSK_M_2003_5.pdf