Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria
Type 2 diabetes mellitus is the predominant type of diabetes mellitus and the type likely to go undiagnosed. Oxidative damage was suggested in the development of diabetic microangiopathic and macroangiopathic complications in these patients. Since the long-term complications are the main cause o...
| Main Author: | |
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| Format: | Thesis |
| Language: | English English |
| Published: |
2001
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| Online Access: | http://psasir.upm.edu.my/id/eprint/11220/ http://psasir.upm.edu.my/id/eprint/11220/1/FPSK_M_2001_8_.pdf |
| _version_ | 1848841589576695808 |
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| author | Sim, Sze Kiat |
| author_facet | Sim, Sze Kiat |
| author_sort | Sim, Sze Kiat |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Type 2 diabetes mellitus is the predominant type of diabetes mellitus
and the type likely to go undiagnosed. Oxidative damage was suggested in
the development of diabetic microangiopathic and macroangiopathic
complications in these patients. Since the long-term complications are the
main cause of morbidity and mortality in diabetic patients, a quantitative
determination of the level of oxidative stress is a valuable indicator of the
degree of the severity of the disease and of the effectiveness of treatment.
The main aim of this study is to evaluate the extent of oxidative DNA damage
with different severity of microalbuminuria in diabetic patients and its
associations with other metabolic controls. The comet assay was adopted to
measure the level of oxidative DNA damage in leukocytes. One hundred and
twenty seven (127) Type 2 diabetic patients with- and without
microalbuminuria were recruited from the Outpatients Department and |
| first_indexed | 2025-11-15T07:45:39Z |
| format | Thesis |
| id | upm-11220 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T07:45:39Z |
| publishDate | 2001 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-112202024-06-12T08:06:53Z http://psasir.upm.edu.my/id/eprint/11220/ Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria Sim, Sze Kiat Type 2 diabetes mellitus is the predominant type of diabetes mellitus and the type likely to go undiagnosed. Oxidative damage was suggested in the development of diabetic microangiopathic and macroangiopathic complications in these patients. Since the long-term complications are the main cause of morbidity and mortality in diabetic patients, a quantitative determination of the level of oxidative stress is a valuable indicator of the degree of the severity of the disease and of the effectiveness of treatment. The main aim of this study is to evaluate the extent of oxidative DNA damage with different severity of microalbuminuria in diabetic patients and its associations with other metabolic controls. The comet assay was adopted to measure the level of oxidative DNA damage in leukocytes. One hundred and twenty seven (127) Type 2 diabetic patients with- and without microalbuminuria were recruited from the Outpatients Department and 2001-06 Thesis NonPeerReviewed text en http://psasir.upm.edu.my/id/eprint/11220/1/FPSK_M_2001_8_.pdf Sim, Sze Kiat (2001) Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria. Masters thesis, Universiti Putra Malaysia. English |
| spellingShingle | Sim, Sze Kiat Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria |
| title | Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria |
| title_full | Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria |
| title_fullStr | Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria |
| title_full_unstemmed | Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria |
| title_short | Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria |
| title_sort | oxidative dna damage in leukocytes and its association with metabolic control in diabetic patients with and without microalbuminuria |
| url | http://psasir.upm.edu.my/id/eprint/11220/ http://psasir.upm.edu.my/id/eprint/11220/1/FPSK_M_2001_8_.pdf |