Spontaneous bilateral basal ganglia haemorrhage secondary to methanol poisoning
Methanol toxicity remains as major problem in the medical field.[1-3] With its active metabolite, formic acid often leads to severe metabolic acidosis and to some extend brain damaged.[4-6] We are reporting a case of brain hemorrhage at the right external capsule and left basal ganglia with mass eff...
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| Format: | Article |
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Medknow
2024
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| Online Access: | http://psasir.upm.edu.my/id/eprint/110572/ |
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| author | Sohor, Norainon J Loh, Wei Chao Pang, Rong Yao Khan, Abdul Hanif Chia, Peck Kee Wan Sulaiman, Wan Aliaa Mat, Liyana Inche Hoo, Fan Kee Basri, Hamidon |
| author_facet | Sohor, Norainon J Loh, Wei Chao Pang, Rong Yao Khan, Abdul Hanif Chia, Peck Kee Wan Sulaiman, Wan Aliaa Mat, Liyana Inche Hoo, Fan Kee Basri, Hamidon |
| author_sort | Sohor, Norainon J |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Methanol toxicity remains as major problem in the medical field.[1-3] With its active metabolite, formic acid often leads to severe metabolic acidosis and to some extend brain damaged.[4-6] We are reporting a case of brain hemorrhage at the right external capsule and left basal ganglia with mass effect and obstructive hydrocephalus in a methanol poisoning patient. A confused 29-year-old gentleman was brought into hospital. Initial investigation showed severe metabolic acidosis with raised anion gap. Initial brain CT scan was normal. Subsequently, serum methanol was reported to be high (112 mg/dL). Intravenous (IV) ethanol 10% was given without any delayed. As there was no improvement in his consciousness level, a repeat brain CT was performed and it showed multiple cerebral hemorrhage with obstructive hydrocephalus. Hence, clinicians should have high index of suspicion for cerebral hemorrhage in a patient with methanol toxicity, who presented with altered mental status and severe metabolic acidosis. |
| first_indexed | 2025-11-15T14:06:32Z |
| format | Article |
| id | upm-110572 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T14:06:32Z |
| publishDate | 2024 |
| publisher | Medknow |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1105722024-06-13T02:59:35Z http://psasir.upm.edu.my/id/eprint/110572/ Spontaneous bilateral basal ganglia haemorrhage secondary to methanol poisoning Sohor, Norainon J Loh, Wei Chao Pang, Rong Yao Khan, Abdul Hanif Chia, Peck Kee Wan Sulaiman, Wan Aliaa Mat, Liyana Inche Hoo, Fan Kee Basri, Hamidon Methanol toxicity remains as major problem in the medical field.[1-3] With its active metabolite, formic acid often leads to severe metabolic acidosis and to some extend brain damaged.[4-6] We are reporting a case of brain hemorrhage at the right external capsule and left basal ganglia with mass effect and obstructive hydrocephalus in a methanol poisoning patient. A confused 29-year-old gentleman was brought into hospital. Initial investigation showed severe metabolic acidosis with raised anion gap. Initial brain CT scan was normal. Subsequently, serum methanol was reported to be high (112 mg/dL). Intravenous (IV) ethanol 10% was given without any delayed. As there was no improvement in his consciousness level, a repeat brain CT was performed and it showed multiple cerebral hemorrhage with obstructive hydrocephalus. Hence, clinicians should have high index of suspicion for cerebral hemorrhage in a patient with methanol toxicity, who presented with altered mental status and severe metabolic acidosis. Medknow 2024 Article PeerReviewed Sohor, Norainon J and Loh, Wei Chao and Pang, Rong Yao and Khan, Abdul Hanif and Chia, Peck Kee and Wan Sulaiman, Wan Aliaa and Mat, Liyana Inche and Hoo, Fan Kee and Basri, Hamidon (2024) Spontaneous bilateral basal ganglia haemorrhage secondary to methanol poisoning. Neurology India, 71 (6). pp. 1260-1262. ISSN 0028-3886; ESSN: 1998-4022 https://journals.lww.com/neur/fulltext/2023/71060/spontaneous_bilateral_basal_ganglia_haemorrhage.29.aspx 10.4103/0028-3886.391392 |
| spellingShingle | Sohor, Norainon J Loh, Wei Chao Pang, Rong Yao Khan, Abdul Hanif Chia, Peck Kee Wan Sulaiman, Wan Aliaa Mat, Liyana Inche Hoo, Fan Kee Basri, Hamidon Spontaneous bilateral basal ganglia haemorrhage secondary to methanol poisoning |
| title | Spontaneous bilateral basal ganglia haemorrhage secondary to methanol poisoning |
| title_full | Spontaneous bilateral basal ganglia haemorrhage secondary to methanol poisoning |
| title_fullStr | Spontaneous bilateral basal ganglia haemorrhage secondary to methanol poisoning |
| title_full_unstemmed | Spontaneous bilateral basal ganglia haemorrhage secondary to methanol poisoning |
| title_short | Spontaneous bilateral basal ganglia haemorrhage secondary to methanol poisoning |
| title_sort | spontaneous bilateral basal ganglia haemorrhage secondary to methanol poisoning |
| url | http://psasir.upm.edu.my/id/eprint/110572/ http://psasir.upm.edu.my/id/eprint/110572/ http://psasir.upm.edu.my/id/eprint/110572/ |