Lateral flow assay: a promising rapid point-of-care testing tool for infections and non-communicable diseases

The point-of-care testing (POCT) approach has established itself as having remarkable importance in diagnosing various infectious and non-communicable diseases (NCDs). The POCT approach has succeeded in meeting the current demand for having diagnostic strategies that can provide fast, sensitive, and...

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Main Authors: Vealan, Kumaravel, Joseph, Narcisse, Alimat, Sharizah, Karumbati, Anandi S., Thilakavathy, Karuppiah
Format: Article
Published: Sciendo 2023
Online Access:http://psasir.upm.edu.my/id/eprint/110539/
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author Vealan, Kumaravel
Joseph, Narcisse
Alimat, Sharizah
Karumbati, Anandi S.
Thilakavathy, Karuppiah
author_facet Vealan, Kumaravel
Joseph, Narcisse
Alimat, Sharizah
Karumbati, Anandi S.
Thilakavathy, Karuppiah
author_sort Vealan, Kumaravel
building UPM Institutional Repository
collection Online Access
description The point-of-care testing (POCT) approach has established itself as having remarkable importance in diagnosing various infectious and non-communicable diseases (NCDs). The POCT approach has succeeded in meeting the current demand for having diagnostic strategies that can provide fast, sensitive, and highly accurate test results without involving complicated procedures. This has been accomplished by introducing rapid bioanalytical tools or biosensors such as lateral flow assays (LFAs). The production cost of these tools is very low, allowing developing countries with limited resources to utilize them or produce them on their own. Thus, their use has grown in various fields in recent years. More importantly, LFAs have created the possibility for a new era of incorporating nanotechnology in disease diagnosis and have already attained significant commercial success worldwide, making POCT an essential approach not just for now but also for the future. In this review, we have provided an overview of POCT and its evolution into the most promising rapid diagnostic approach. We also elaborate on LFAs with a special focus on nucleic acid LFAs.
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spelling upm-1105392024-06-13T03:11:26Z http://psasir.upm.edu.my/id/eprint/110539/ Lateral flow assay: a promising rapid point-of-care testing tool for infections and non-communicable diseases Vealan, Kumaravel Joseph, Narcisse Alimat, Sharizah Karumbati, Anandi S. Thilakavathy, Karuppiah The point-of-care testing (POCT) approach has established itself as having remarkable importance in diagnosing various infectious and non-communicable diseases (NCDs). The POCT approach has succeeded in meeting the current demand for having diagnostic strategies that can provide fast, sensitive, and highly accurate test results without involving complicated procedures. This has been accomplished by introducing rapid bioanalytical tools or biosensors such as lateral flow assays (LFAs). The production cost of these tools is very low, allowing developing countries with limited resources to utilize them or produce them on their own. Thus, their use has grown in various fields in recent years. More importantly, LFAs have created the possibility for a new era of incorporating nanotechnology in disease diagnosis and have already attained significant commercial success worldwide, making POCT an essential approach not just for now but also for the future. In this review, we have provided an overview of POCT and its evolution into the most promising rapid diagnostic approach. We also elaborate on LFAs with a special focus on nucleic acid LFAs. Sciendo 2023 Article PeerReviewed Vealan, Kumaravel and Joseph, Narcisse and Alimat, Sharizah and Karumbati, Anandi S. and Thilakavathy, Karuppiah (2023) Lateral flow assay: a promising rapid point-of-care testing tool for infections and non-communicable diseases. Asian Biomedicine, 17 (6). pp. 250-266. ISSN 1905-7415; ESSN: 1875-855X https://sciendo.com/article/10.2478/abm-2023-0068 10.2478/abm-2023-0068
spellingShingle Vealan, Kumaravel
Joseph, Narcisse
Alimat, Sharizah
Karumbati, Anandi S.
Thilakavathy, Karuppiah
Lateral flow assay: a promising rapid point-of-care testing tool for infections and non-communicable diseases
title Lateral flow assay: a promising rapid point-of-care testing tool for infections and non-communicable diseases
title_full Lateral flow assay: a promising rapid point-of-care testing tool for infections and non-communicable diseases
title_fullStr Lateral flow assay: a promising rapid point-of-care testing tool for infections and non-communicable diseases
title_full_unstemmed Lateral flow assay: a promising rapid point-of-care testing tool for infections and non-communicable diseases
title_short Lateral flow assay: a promising rapid point-of-care testing tool for infections and non-communicable diseases
title_sort lateral flow assay: a promising rapid point-of-care testing tool for infections and non-communicable diseases
url http://psasir.upm.edu.my/id/eprint/110539/
http://psasir.upm.edu.my/id/eprint/110539/
http://psasir.upm.edu.my/id/eprint/110539/