Isolation of phytochemical and pharmacological bioactive compounds from Mitragyna speciosa (Korth.): a scoping review
Introduction: This scoping review aimed to provide a comprehensive summary and evaluation of solvents and methods for the extraction of bioactive compounds with pharmacological properties from Mitragyna speciosa (M. speciosa) Korth. Methods: The relevant articles were screened on electronic database...
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| Format: | Article |
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Universiti Putra Malaysia
2023
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| Online Access: | http://psasir.upm.edu.my/id/eprint/110520/ |
| _version_ | 1848865538478964736 |
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| author | Kalifa Kafo, Anwar Salm Mahayidin, Hasni Zailan, Nur Fatin Zalikha Zaidan, Uswatun Hasanah Syed Azhar, Sharifah Nurfadhlin Afifah Ramasamy, Rajesh Hassan, Masriana |
| author_facet | Kalifa Kafo, Anwar Salm Mahayidin, Hasni Zailan, Nur Fatin Zalikha Zaidan, Uswatun Hasanah Syed Azhar, Sharifah Nurfadhlin Afifah Ramasamy, Rajesh Hassan, Masriana |
| author_sort | Kalifa Kafo, Anwar Salm |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Introduction: This scoping review aimed to provide a comprehensive summary and evaluation of solvents and methods for the extraction of bioactive compounds with pharmacological properties from Mitragyna speciosa (M. speciosa) Korth. Methods: The relevant articles were screened on electronic databases such as Scopus, PubMed, and Science Direct and verified their qualities based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) guideline. Results: We selected 41 articles according to two features; the extraction of bioactive compounds and pharmacological properties of M. speciosa extract that involved different solvents and methods. Evidence shows that methanol was the commonly used solvent along with the maceration process in the extraction of M. speciosa to obtain valuable bioactive compounds with clinical benefits. Alternatively, Soxhlet provides less exertion to the extraction process with similar value. Conclusion: Despite various potential modern techniques and solvents available, the synergy between traditional maceration and Soxhlet and methanol was found to potentially attain pharmacological values and bioactive substances in M. speciosa. |
| first_indexed | 2025-11-15T14:06:18Z |
| format | Article |
| id | upm-110520 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T14:06:18Z |
| publishDate | 2023 |
| publisher | Universiti Putra Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1105202024-05-27T08:49:03Z http://psasir.upm.edu.my/id/eprint/110520/ Isolation of phytochemical and pharmacological bioactive compounds from Mitragyna speciosa (Korth.): a scoping review Kalifa Kafo, Anwar Salm Mahayidin, Hasni Zailan, Nur Fatin Zalikha Zaidan, Uswatun Hasanah Syed Azhar, Sharifah Nurfadhlin Afifah Ramasamy, Rajesh Hassan, Masriana Introduction: This scoping review aimed to provide a comprehensive summary and evaluation of solvents and methods for the extraction of bioactive compounds with pharmacological properties from Mitragyna speciosa (M. speciosa) Korth. Methods: The relevant articles were screened on electronic databases such as Scopus, PubMed, and Science Direct and verified their qualities based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) guideline. Results: We selected 41 articles according to two features; the extraction of bioactive compounds and pharmacological properties of M. speciosa extract that involved different solvents and methods. Evidence shows that methanol was the commonly used solvent along with the maceration process in the extraction of M. speciosa to obtain valuable bioactive compounds with clinical benefits. Alternatively, Soxhlet provides less exertion to the extraction process with similar value. Conclusion: Despite various potential modern techniques and solvents available, the synergy between traditional maceration and Soxhlet and methanol was found to potentially attain pharmacological values and bioactive substances in M. speciosa. Universiti Putra Malaysia 2023 Article PeerReviewed Kalifa Kafo, Anwar Salm and Mahayidin, Hasni and Zailan, Nur Fatin Zalikha and Zaidan, Uswatun Hasanah and Syed Azhar, Sharifah Nurfadhlin Afifah and Ramasamy, Rajesh and Hassan, Masriana (2023) Isolation of phytochemical and pharmacological bioactive compounds from Mitragyna speciosa (Korth.): a scoping review. Malaysian Journal of Medicine and Health Sciences, 19. art. no. suppl.16. 38- 47. ISSN 1675-8544; ESSN: 2636-9346 https://medic.upm.edu.my/upload/dokumen/2023122608271706_2023-0935.pdf 10.47836/mjmhs.19.s16.7 |
| spellingShingle | Kalifa Kafo, Anwar Salm Mahayidin, Hasni Zailan, Nur Fatin Zalikha Zaidan, Uswatun Hasanah Syed Azhar, Sharifah Nurfadhlin Afifah Ramasamy, Rajesh Hassan, Masriana Isolation of phytochemical and pharmacological bioactive compounds from Mitragyna speciosa (Korth.): a scoping review |
| title | Isolation of phytochemical and pharmacological bioactive compounds from Mitragyna speciosa (Korth.): a scoping review |
| title_full | Isolation of phytochemical and pharmacological bioactive compounds from Mitragyna speciosa (Korth.): a scoping review |
| title_fullStr | Isolation of phytochemical and pharmacological bioactive compounds from Mitragyna speciosa (Korth.): a scoping review |
| title_full_unstemmed | Isolation of phytochemical and pharmacological bioactive compounds from Mitragyna speciosa (Korth.): a scoping review |
| title_short | Isolation of phytochemical and pharmacological bioactive compounds from Mitragyna speciosa (Korth.): a scoping review |
| title_sort | isolation of phytochemical and pharmacological bioactive compounds from mitragyna speciosa (korth.): a scoping review |
| url | http://psasir.upm.edu.my/id/eprint/110520/ http://psasir.upm.edu.my/id/eprint/110520/ http://psasir.upm.edu.my/id/eprint/110520/ |