The global prevalence of gallstones in pregnancy: a systematic review and meta-analysis
Background: Gallstone disease is the second most common non-gynecological disease that may require surgical intervention during pregnancy. This study investigates the global prevalence of gallstones in pregnancy through a systematic review and meta-analysis. Methods: A systematic review and meta-ana...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier Ireland
2023
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| Online Access: | http://psasir.upm.edu.my/id/eprint/110466/ http://psasir.upm.edu.my/id/eprint/110466/1/110466.pdf |
| _version_ | 1848867721200009216 |
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| author | Salari, Nader Hasheminezhad, Razie Heidarisharaf, Parisa Khaleghi, Ali Asghar Azizi, Arezou Haji Shohaimi, Shamarina Mohammadi, Masoud |
| author_facet | Salari, Nader Hasheminezhad, Razie Heidarisharaf, Parisa Khaleghi, Ali Asghar Azizi, Arezou Haji Shohaimi, Shamarina Mohammadi, Masoud |
| author_sort | Salari, Nader |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Background: Gallstone disease is the second most common non-gynecological disease that may require surgical intervention during pregnancy. This study investigates the global prevalence of gallstones in pregnancy through a systematic review and meta-analysis. Methods: A systematic review and meta-analysis of studies that reported the global prevalence of gallstones in pregnancy was conducted. PubMed, Scopus, Web of Science, Embase, ScienceDirect, and Google Scholar were searched for studies published up to September 2022. Results: In a review of 31 studies with a sample size of 190,714 people, the I2 heterogeneity test showed high heterogeneity (I2 = 98.8%). Therefore, the random effects method was used to analyze the results. The prevalence of gallstones was reported as 3.6% (95% CI: 1.9–6.7%). The highest prevalence of gallstones by continent was reported in America, at 6.8% (95% CI: 4.2–10.8%). The Egger test showed no evidence of publication bias (p = 0.609). Conclusion: Based on the results of this study, health policymakers should emphasize to the target community and the medical staff dealing with pregnant women the importance of screening for gallstones during pregnancy. |
| first_indexed | 2025-11-15T14:41:00Z |
| format | Article |
| id | upm-110466 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T14:41:00Z |
| publishDate | 2023 |
| publisher | Elsevier Ireland |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1104662025-09-18T07:24:10Z http://psasir.upm.edu.my/id/eprint/110466/ The global prevalence of gallstones in pregnancy: a systematic review and meta-analysis Salari, Nader Hasheminezhad, Razie Heidarisharaf, Parisa Khaleghi, Ali Asghar Azizi, Arezou Haji Shohaimi, Shamarina Mohammadi, Masoud Background: Gallstone disease is the second most common non-gynecological disease that may require surgical intervention during pregnancy. This study investigates the global prevalence of gallstones in pregnancy through a systematic review and meta-analysis. Methods: A systematic review and meta-analysis of studies that reported the global prevalence of gallstones in pregnancy was conducted. PubMed, Scopus, Web of Science, Embase, ScienceDirect, and Google Scholar were searched for studies published up to September 2022. Results: In a review of 31 studies with a sample size of 190,714 people, the I2 heterogeneity test showed high heterogeneity (I2 = 98.8%). Therefore, the random effects method was used to analyze the results. The prevalence of gallstones was reported as 3.6% (95% CI: 1.9–6.7%). The highest prevalence of gallstones by continent was reported in America, at 6.8% (95% CI: 4.2–10.8%). The Egger test showed no evidence of publication bias (p = 0.609). Conclusion: Based on the results of this study, health policymakers should emphasize to the target community and the medical staff dealing with pregnant women the importance of screening for gallstones during pregnancy. Elsevier Ireland 2023 Article PeerReviewed text en cc_by_nc_nd_4 http://psasir.upm.edu.my/id/eprint/110466/1/110466.pdf Salari, Nader and Hasheminezhad, Razie and Heidarisharaf, Parisa and Khaleghi, Ali Asghar and Azizi, Arezou Haji and Shohaimi, Shamarina and Mohammadi, Masoud (2023) The global prevalence of gallstones in pregnancy: a systematic review and meta-analysis. European Journal of Obstetrics and Gynecology and Reproductive Biology: X, 19. art. no. 100237. pp. 1-7. ISSN 2590-1613 https://www.sciencedirect.com/science/article/pii/S2590161323000625?via%3Dihub 10.1016/j.eurox.2023.100237 |
| spellingShingle | Salari, Nader Hasheminezhad, Razie Heidarisharaf, Parisa Khaleghi, Ali Asghar Azizi, Arezou Haji Shohaimi, Shamarina Mohammadi, Masoud The global prevalence of gallstones in pregnancy: a systematic review and meta-analysis |
| title | The global prevalence of gallstones in pregnancy: a systematic review and meta-analysis |
| title_full | The global prevalence of gallstones in pregnancy: a systematic review and meta-analysis |
| title_fullStr | The global prevalence of gallstones in pregnancy: a systematic review and meta-analysis |
| title_full_unstemmed | The global prevalence of gallstones in pregnancy: a systematic review and meta-analysis |
| title_short | The global prevalence of gallstones in pregnancy: a systematic review and meta-analysis |
| title_sort | global prevalence of gallstones in pregnancy: a systematic review and meta-analysis |
| url | http://psasir.upm.edu.my/id/eprint/110466/ http://psasir.upm.edu.my/id/eprint/110466/ http://psasir.upm.edu.my/id/eprint/110466/ http://psasir.upm.edu.my/id/eprint/110466/1/110466.pdf |