The association between serum magnesium and type 2 Diabetes mellitus in adult patients at a tertiary hospital in Malaysia
Introduction: Magnesium (Mg) has an important role in glucose metabolism and acts as a cofactor for many enzymatic reactions. However, Mg deficiency frequently goes unnoticed. The aim of this study was to determine the association between serum Mg and type 2 diabetes mellitus (T2DM). Methods: A cros...
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| Format: | Article |
| Language: | English |
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Fakulti Perubatan dan Sains Kesihatan, UPM
2023
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| Online Access: | http://psasir.upm.edu.my/id/eprint/110393/ http://psasir.upm.edu.my/id/eprint/110393/1/110393.pdf |
| _version_ | 1848865512635760640 |
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| author | Hashim, Nurul Hidayah C. Thambiah, Subashini Masiman, Ana Daliela Samsuddin, Intan Nureslyna Zahari Sham, Siti Yazmin Osman, Malina Lai, Yin Ye |
| author_facet | Hashim, Nurul Hidayah C. Thambiah, Subashini Masiman, Ana Daliela Samsuddin, Intan Nureslyna Zahari Sham, Siti Yazmin Osman, Malina Lai, Yin Ye |
| author_sort | Hashim, Nurul Hidayah |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Introduction: Magnesium (Mg) has an important role in glucose metabolism and acts as a cofactor for many enzymatic reactions. However, Mg deficiency frequently goes unnoticed. The aim of this study was to determine the association between serum Mg and type 2 diabetes mellitus (T2DM). Methods: A cross-sectional study was done among T2DM patients who were followed-up at the Diabetic Clinic at Hospital Melaka. Serum Mg test was added to the routine investigations of all patients with diabetes who participated. Results: Prevalence of hypomagnesaemia was 21.5. There was a significant difference in age, duration of T2DM and diabetic complications that include retinopathy, neuropathy, nephropathy, coronary heart disease and cerebrovascular accident as well as all laboratory parameters except high-density lipoprotein cholesterol between the hypomagnesaemia and normomagnesaemia groups. Glycated haemoglobin (HbA1c), fasting plasma glucose and duration of diabetes independently predicted serum Mg levels in T2DM patients. Conclusion: These find- ings support the use of serum Mg as an indirect biomarker of glycaemic control in T2DM patients, whereby hypomagnesaemia indicates poor control. |
| first_indexed | 2025-11-15T14:05:53Z |
| format | Article |
| id | upm-110393 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T14:05:53Z |
| publishDate | 2023 |
| publisher | Fakulti Perubatan dan Sains Kesihatan, UPM |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1103932025-05-14T07:52:12Z http://psasir.upm.edu.my/id/eprint/110393/ The association between serum magnesium and type 2 Diabetes mellitus in adult patients at a tertiary hospital in Malaysia Hashim, Nurul Hidayah C. Thambiah, Subashini Masiman, Ana Daliela Samsuddin, Intan Nureslyna Zahari Sham, Siti Yazmin Osman, Malina Lai, Yin Ye Introduction: Magnesium (Mg) has an important role in glucose metabolism and acts as a cofactor for many enzymatic reactions. However, Mg deficiency frequently goes unnoticed. The aim of this study was to determine the association between serum Mg and type 2 diabetes mellitus (T2DM). Methods: A cross-sectional study was done among T2DM patients who were followed-up at the Diabetic Clinic at Hospital Melaka. Serum Mg test was added to the routine investigations of all patients with diabetes who participated. Results: Prevalence of hypomagnesaemia was 21.5. There was a significant difference in age, duration of T2DM and diabetic complications that include retinopathy, neuropathy, nephropathy, coronary heart disease and cerebrovascular accident as well as all laboratory parameters except high-density lipoprotein cholesterol between the hypomagnesaemia and normomagnesaemia groups. Glycated haemoglobin (HbA1c), fasting plasma glucose and duration of diabetes independently predicted serum Mg levels in T2DM patients. Conclusion: These find- ings support the use of serum Mg as an indirect biomarker of glycaemic control in T2DM patients, whereby hypomagnesaemia indicates poor control. Fakulti Perubatan dan Sains Kesihatan, UPM 2023 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/110393/1/110393.pdf Hashim, Nurul Hidayah and C. Thambiah, Subashini and Masiman, Ana Daliela and Samsuddin, Intan Nureslyna and Zahari Sham, Siti Yazmin and Osman, Malina and Lai, Yin Ye (2023) The association between serum magnesium and type 2 Diabetes mellitus in adult patients at a tertiary hospital in Malaysia. Malaysian Journal of Medicine and Health Sciences, 19 (suppl.16). pp. 29-36. ISSN 2636-9346 https://medic.upm.edu.my/jurnal_kami/volume_19_2023/mjmhs_vol19_supp_16_december_2023-77004 10.47836/mjmhs.19.s16.5 |
| spellingShingle | Hashim, Nurul Hidayah C. Thambiah, Subashini Masiman, Ana Daliela Samsuddin, Intan Nureslyna Zahari Sham, Siti Yazmin Osman, Malina Lai, Yin Ye The association between serum magnesium and type 2 Diabetes mellitus in adult patients at a tertiary hospital in Malaysia |
| title | The association between serum magnesium and type 2 Diabetes mellitus in adult patients at a tertiary hospital in Malaysia |
| title_full | The association between serum magnesium and type 2 Diabetes mellitus in adult patients at a tertiary hospital in Malaysia |
| title_fullStr | The association between serum magnesium and type 2 Diabetes mellitus in adult patients at a tertiary hospital in Malaysia |
| title_full_unstemmed | The association between serum magnesium and type 2 Diabetes mellitus in adult patients at a tertiary hospital in Malaysia |
| title_short | The association between serum magnesium and type 2 Diabetes mellitus in adult patients at a tertiary hospital in Malaysia |
| title_sort | association between serum magnesium and type 2 diabetes mellitus in adult patients at a tertiary hospital in malaysia |
| url | http://psasir.upm.edu.my/id/eprint/110393/ http://psasir.upm.edu.my/id/eprint/110393/ http://psasir.upm.edu.my/id/eprint/110393/ http://psasir.upm.edu.my/id/eprint/110393/1/110393.pdf |