Relationship between benzene concentration, MDA levels and kidney function in car painting workshops in Surabaya: a cross-sectional observational study

Background: Car painting workers are at risk because of the use of solvents containing benzene as the main ingredient in the car painting process. One of the clinical effects of systemic benzene is kidney disorders. Therefore, the purpose of this study is to analyze the relationship between benzene...

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Main Authors: Tualeka, Abdul Rohim, Aziz, Mohd Yusmaidie, Perumal, Velu, Thamaraikani, Tamilanban, Rosnon, Roslan, Novianti, Salsabila, Rahmawati, Pudji, Ahsan, Ahsan
Format: Article
Language:English
Published: Taylor and Francis 2024
Online Access:http://psasir.upm.edu.my/id/eprint/110388/
http://psasir.upm.edu.my/id/eprint/110388/1/110388.pdf
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author Tualeka, Abdul Rohim
Aziz, Mohd Yusmaidie
Perumal, Velu
Thamaraikani, Tamilanban
Rosnon, Roslan
Novianti, Salsabila
Rahmawati, Pudji
Ahsan, Ahsan
author_facet Tualeka, Abdul Rohim
Aziz, Mohd Yusmaidie
Perumal, Velu
Thamaraikani, Tamilanban
Rosnon, Roslan
Novianti, Salsabila
Rahmawati, Pudji
Ahsan, Ahsan
author_sort Tualeka, Abdul Rohim
building UPM Institutional Repository
collection Online Access
description Background: Car painting workers are at risk because of the use of solvents containing benzene as the main ingredient in the car painting process. One of the clinical effects of systemic benzene is kidney disorders. Therefore, the purpose of this study is to analyze the relationship between benzene and Risk Quotient (RQ) benzene concentrations with Malondialdehyde (MDA), Blood Urea Nitrogen (BUN), and creatinine levels in workers exposed to benzene in car painting workshops in Surabaya. Methods: This is an observational, cross-sectional study conducted at two car painting workshops in Surabaya that use benzene as a solvent in their production process, namely in industries in Kalijudan and Jemursari. The research sample was taken using the accidental sampling method and as many as 30 respondents were involved in this study. The variables studied included benzene concentration, RQ benzene, MDA levels, and kidney function (BUN and creatinine levels). Analysis of the data used is a descriptive and bivariate analysis using the Pearson correlation test. Results: There was no significant relationship between concentrations, RQ benzene, and MDA levels in workers in painting in Surabaya (p> 0.05). There was no significant relationship between benzene concentration, BUN levels, and creatinine levels in paint workers in Surabaya (p> 0.05). There was no significant relationship between benzene RQ and BUN and creatinine levels in paint workers in Surabaya (p> 0.05). Conclusions: The results of this study indicate that the effects of benzene do not lead to impaired kidney function. The benzene RQ variable in this study did not become a determining factor in BUN and creatinine levels in workers.
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spelling upm-1103882024-10-23T07:17:32Z http://psasir.upm.edu.my/id/eprint/110388/ Relationship between benzene concentration, MDA levels and kidney function in car painting workshops in Surabaya: a cross-sectional observational study Tualeka, Abdul Rohim Aziz, Mohd Yusmaidie Perumal, Velu Thamaraikani, Tamilanban Rosnon, Roslan Novianti, Salsabila Rahmawati, Pudji Ahsan, Ahsan Background: Car painting workers are at risk because of the use of solvents containing benzene as the main ingredient in the car painting process. One of the clinical effects of systemic benzene is kidney disorders. Therefore, the purpose of this study is to analyze the relationship between benzene and Risk Quotient (RQ) benzene concentrations with Malondialdehyde (MDA), Blood Urea Nitrogen (BUN), and creatinine levels in workers exposed to benzene in car painting workshops in Surabaya. Methods: This is an observational, cross-sectional study conducted at two car painting workshops in Surabaya that use benzene as a solvent in their production process, namely in industries in Kalijudan and Jemursari. The research sample was taken using the accidental sampling method and as many as 30 respondents were involved in this study. The variables studied included benzene concentration, RQ benzene, MDA levels, and kidney function (BUN and creatinine levels). Analysis of the data used is a descriptive and bivariate analysis using the Pearson correlation test. Results: There was no significant relationship between concentrations, RQ benzene, and MDA levels in workers in painting in Surabaya (p> 0.05). There was no significant relationship between benzene concentration, BUN levels, and creatinine levels in paint workers in Surabaya (p> 0.05). There was no significant relationship between benzene RQ and BUN and creatinine levels in paint workers in Surabaya (p> 0.05). Conclusions: The results of this study indicate that the effects of benzene do not lead to impaired kidney function. The benzene RQ variable in this study did not become a determining factor in BUN and creatinine levels in workers. Taylor and Francis 2024-06 Article PeerReviewed text en cc_by_4 http://psasir.upm.edu.my/id/eprint/110388/1/110388.pdf Tualeka, Abdul Rohim and Aziz, Mohd Yusmaidie and Perumal, Velu and Thamaraikani, Tamilanban and Rosnon, Roslan and Novianti, Salsabila and Rahmawati, Pudji and Ahsan, Ahsan (2024) Relationship between benzene concentration, MDA levels and kidney function in car painting workshops in Surabaya: a cross-sectional observational study. F1000Research. pp. 1-10. ISSN 2046-1402 https://f1000research.com/articles/12-1419/v2 10.12688/f1000research.140287.1
spellingShingle Tualeka, Abdul Rohim
Aziz, Mohd Yusmaidie
Perumal, Velu
Thamaraikani, Tamilanban
Rosnon, Roslan
Novianti, Salsabila
Rahmawati, Pudji
Ahsan, Ahsan
Relationship between benzene concentration, MDA levels and kidney function in car painting workshops in Surabaya: a cross-sectional observational study
title Relationship between benzene concentration, MDA levels and kidney function in car painting workshops in Surabaya: a cross-sectional observational study
title_full Relationship between benzene concentration, MDA levels and kidney function in car painting workshops in Surabaya: a cross-sectional observational study
title_fullStr Relationship between benzene concentration, MDA levels and kidney function in car painting workshops in Surabaya: a cross-sectional observational study
title_full_unstemmed Relationship between benzene concentration, MDA levels and kidney function in car painting workshops in Surabaya: a cross-sectional observational study
title_short Relationship between benzene concentration, MDA levels and kidney function in car painting workshops in Surabaya: a cross-sectional observational study
title_sort relationship between benzene concentration, mda levels and kidney function in car painting workshops in surabaya: a cross-sectional observational study
url http://psasir.upm.edu.my/id/eprint/110388/
http://psasir.upm.edu.my/id/eprint/110388/
http://psasir.upm.edu.my/id/eprint/110388/
http://psasir.upm.edu.my/id/eprint/110388/1/110388.pdf