Performance of biomass and exopolysaccharide production from the medicinal mushroom Ganoderma lucidum in a new fabricated Air-L-Shaped Bioreactor (ALSB)

Conventional stirred-tank bioreactor (STR) designs are optimised for cultures of bacteria but not fungal cultures; therefore, a new Air-L-Shaped Bioreactor (ALSB) was fabricated. The ALSB was designed to eliminate the wall growth and clumping of fungal mycelium in STRs. Ganoderma lucidum was used as...

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Main Authors: Supramani, Sugenendran, Rejab, Nur Ardiyana, Ilham, Zul, Ahmad, Rahayu, Show, Pau-Loke, Ibrahim, Mohamad Faizal, Wan Mohtar, Wan Abd Al Qadr Imad
Format: Article
Language:English
Published: Multidisciplinary Digital Publishing Institute (MDPI) 2023
Online Access:http://psasir.upm.edu.my/id/eprint/110363/
http://psasir.upm.edu.my/id/eprint/110363/1/110363.pdf
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author Supramani, Sugenendran
Rejab, Nur Ardiyana
Ilham, Zul
Ahmad, Rahayu
Show, Pau-Loke
Ibrahim, Mohamad Faizal
Wan Mohtar, Wan Abd Al Qadr Imad
author_facet Supramani, Sugenendran
Rejab, Nur Ardiyana
Ilham, Zul
Ahmad, Rahayu
Show, Pau-Loke
Ibrahim, Mohamad Faizal
Wan Mohtar, Wan Abd Al Qadr Imad
author_sort Supramani, Sugenendran
building UPM Institutional Repository
collection Online Access
description Conventional stirred-tank bioreactor (STR) designs are optimised for cultures of bacteria but not fungal cultures; therefore, a new Air-L-Shaped Bioreactor (ALSB) was fabricated. The ALSB was designed to eliminate the wall growth and clumping of fungal mycelium in STRs. Ganoderma lucidum was used as a fungal model and its biomass and exopolysaccharide (EPS) production were maximised by optimising the agitation rate, glucose concentration, initial pH, and aeration via response surface methodology (RSM). The ALSB system generated 7.8 g/L of biomass (biomass optimised conditions: 110 rpm, 24 g/L glucose, pH 5.6, and 3 v/v of aeration) and 4.4 g/L of EPS (EPS optimised conditions: 90 rpm, 30 g/L glucose, pH 4, and 2.5 v/v of aeration). In combination, for both optimised conditions, biomass (7.9 g/L) and EPS (4.6 g/L) were produced at 110 rpm, 30 g/L glucose, pH 4, and 3 v/v of aeration with minimal wall growth. The data prove that the ALSB is a blueprint for efficient economical fungal cultivation.
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publisher Multidisciplinary Digital Publishing Institute (MDPI)
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spelling upm-1103632024-10-09T02:21:03Z http://psasir.upm.edu.my/id/eprint/110363/ Performance of biomass and exopolysaccharide production from the medicinal mushroom Ganoderma lucidum in a new fabricated Air-L-Shaped Bioreactor (ALSB) Supramani, Sugenendran Rejab, Nur Ardiyana Ilham, Zul Ahmad, Rahayu Show, Pau-Loke Ibrahim, Mohamad Faizal Wan Mohtar, Wan Abd Al Qadr Imad Conventional stirred-tank bioreactor (STR) designs are optimised for cultures of bacteria but not fungal cultures; therefore, a new Air-L-Shaped Bioreactor (ALSB) was fabricated. The ALSB was designed to eliminate the wall growth and clumping of fungal mycelium in STRs. Ganoderma lucidum was used as a fungal model and its biomass and exopolysaccharide (EPS) production were maximised by optimising the agitation rate, glucose concentration, initial pH, and aeration via response surface methodology (RSM). The ALSB system generated 7.8 g/L of biomass (biomass optimised conditions: 110 rpm, 24 g/L glucose, pH 5.6, and 3 v/v of aeration) and 4.4 g/L of EPS (EPS optimised conditions: 90 rpm, 30 g/L glucose, pH 4, and 2.5 v/v of aeration). In combination, for both optimised conditions, biomass (7.9 g/L) and EPS (4.6 g/L) were produced at 110 rpm, 30 g/L glucose, pH 4, and 3 v/v of aeration with minimal wall growth. The data prove that the ALSB is a blueprint for efficient economical fungal cultivation. Multidisciplinary Digital Publishing Institute (MDPI) 2023 Article PeerReviewed text en cc_by_4 http://psasir.upm.edu.my/id/eprint/110363/1/110363.pdf Supramani, Sugenendran and Rejab, Nur Ardiyana and Ilham, Zul and Ahmad, Rahayu and Show, Pau-Loke and Ibrahim, Mohamad Faizal and Wan Mohtar, Wan Abd Al Qadr Imad (2023) Performance of biomass and exopolysaccharide production from the medicinal mushroom Ganoderma lucidum in a new fabricated Air-L-Shaped Bioreactor (ALSB). Processes, 11 (670). pp. 1-14. ISSN 2227-9717 https://www.mdpi.com/2227-9717/11/3/670 10.3390/pr11030670
spellingShingle Supramani, Sugenendran
Rejab, Nur Ardiyana
Ilham, Zul
Ahmad, Rahayu
Show, Pau-Loke
Ibrahim, Mohamad Faizal
Wan Mohtar, Wan Abd Al Qadr Imad
Performance of biomass and exopolysaccharide production from the medicinal mushroom Ganoderma lucidum in a new fabricated Air-L-Shaped Bioreactor (ALSB)
title Performance of biomass and exopolysaccharide production from the medicinal mushroom Ganoderma lucidum in a new fabricated Air-L-Shaped Bioreactor (ALSB)
title_full Performance of biomass and exopolysaccharide production from the medicinal mushroom Ganoderma lucidum in a new fabricated Air-L-Shaped Bioreactor (ALSB)
title_fullStr Performance of biomass and exopolysaccharide production from the medicinal mushroom Ganoderma lucidum in a new fabricated Air-L-Shaped Bioreactor (ALSB)
title_full_unstemmed Performance of biomass and exopolysaccharide production from the medicinal mushroom Ganoderma lucidum in a new fabricated Air-L-Shaped Bioreactor (ALSB)
title_short Performance of biomass and exopolysaccharide production from the medicinal mushroom Ganoderma lucidum in a new fabricated Air-L-Shaped Bioreactor (ALSB)
title_sort performance of biomass and exopolysaccharide production from the medicinal mushroom ganoderma lucidum in a new fabricated air-l-shaped bioreactor (alsb)
url http://psasir.upm.edu.my/id/eprint/110363/
http://psasir.upm.edu.my/id/eprint/110363/
http://psasir.upm.edu.my/id/eprint/110363/
http://psasir.upm.edu.my/id/eprint/110363/1/110363.pdf