Probing the substrate binding modes and catalytic mechanisms of bleg-1, a promiscuous b3 metallo-β-lactamase with glyoxalase ii properties

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Probing the substrate binding modes and catalytic mechanisms of bleg-1, a promiscuous b3 metallo-β-lactamase with glyoxalase ii properties

BLEG-1 from <jats:italic>Bacillus lehensis</jats:italic> G1 is an evolutionary divergent B3 metallo-β-lactamase (MBL) that exhibited both β-lactamase and glyoxalase II (GLXII) activities. Sequence, phylogeny, biochemical and structural relatedness of BLEG-1 to B3 MBL and...

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Bibliographic Details
Main Authors:	Au, Shaw Xian, Mohd Padzil, Azyyati, Muhd Noor, Noor Dina, Matsumura, Hiroyoshi, Raja Abdul Rahman, Raja Noor Zaliha, Normi, Yahaya M.
Format:	Article
Language:	English
Published:	Public Library of Science 2023
Online Access:	http://psasir.upm.edu.my/id/eprint/110023/ http://psasir.upm.edu.my/id/eprint/110023/1/journal.pone.0291012.pdf

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