Langerhans cell histiocytosis mimicking otitis media
Langerhans cell histiocytosis (LCH) is a spectrum of disease characterised by proliferation of Langerhans cells causing local or systemic manifestations. We report a two-year old boy who presented with a two-month history of progressive painless swelling over the right zygomatic region with ipsilat...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Universiti Putra Malaysia
2023
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| Online Access: | http://psasir.upm.edu.my/id/eprint/109086/ http://psasir.upm.edu.my/id/eprint/109086/1/2023122923461007_MJMHS_0728.pdf |
| _version_ | 1848865280024903680 |
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| author | Ishak, Noor Liza Tan, Sui Teng Hassan, Nor Eyzawiah Alias, Azila |
| author_facet | Ishak, Noor Liza Tan, Sui Teng Hassan, Nor Eyzawiah Alias, Azila |
| author_sort | Ishak, Noor Liza |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Langerhans cell histiocytosis (LCH) is a spectrum of disease characterised by proliferation of Langerhans cells causing local or systemic manifestations. We report a two-year old boy who presented with a two-month history of progressive painless swelling over the right zygomatic region with ipsilateral otorrhea. Radiological investigation revealed an expansile hypodense lesion within the temporal bone with erosion of surrounding structures and meningeal enhancement. An ultrasound-guided biopsy of the lesion confirmed the diagnosis of LCH. LCH of the temporal bone may masquerade as otitis media with intra-temporal complications. A high index of suspicion is essential to avoid delay in diagnosis and management. |
| first_indexed | 2025-11-15T14:02:12Z |
| format | Article |
| id | upm-109086 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T14:02:12Z |
| publishDate | 2023 |
| publisher | Universiti Putra Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1090862024-10-15T02:21:34Z http://psasir.upm.edu.my/id/eprint/109086/ Langerhans cell histiocytosis mimicking otitis media Ishak, Noor Liza Tan, Sui Teng Hassan, Nor Eyzawiah Alias, Azila Langerhans cell histiocytosis (LCH) is a spectrum of disease characterised by proliferation of Langerhans cells causing local or systemic manifestations. We report a two-year old boy who presented with a two-month history of progressive painless swelling over the right zygomatic region with ipsilateral otorrhea. Radiological investigation revealed an expansile hypodense lesion within the temporal bone with erosion of surrounding structures and meningeal enhancement. An ultrasound-guided biopsy of the lesion confirmed the diagnosis of LCH. LCH of the temporal bone may masquerade as otitis media with intra-temporal complications. A high index of suspicion is essential to avoid delay in diagnosis and management. Universiti Putra Malaysia 2023-12 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/109086/1/2023122923461007_MJMHS_0728.pdf Ishak, Noor Liza and Tan, Sui Teng and Hassan, Nor Eyzawiah and Alias, Azila (2023) Langerhans cell histiocytosis mimicking otitis media. Malaysian Journal of Medicine and Health Sciences, 19 (supp.19). pp. 25-27. ISSN 1675-8544; ESSN: 2636-9346 https://medic.upm.edu.my/upload/dokumen/2023122923461007_MJMHS_0728.pdf 10.47836/mjmhs.19.s19.7 |
| spellingShingle | Ishak, Noor Liza Tan, Sui Teng Hassan, Nor Eyzawiah Alias, Azila Langerhans cell histiocytosis mimicking otitis media |
| title | Langerhans cell histiocytosis mimicking otitis media |
| title_full | Langerhans cell histiocytosis mimicking otitis media |
| title_fullStr | Langerhans cell histiocytosis mimicking otitis media |
| title_full_unstemmed | Langerhans cell histiocytosis mimicking otitis media |
| title_short | Langerhans cell histiocytosis mimicking otitis media |
| title_sort | langerhans cell histiocytosis mimicking otitis media |
| url | http://psasir.upm.edu.my/id/eprint/109086/ http://psasir.upm.edu.my/id/eprint/109086/ http://psasir.upm.edu.my/id/eprint/109086/ http://psasir.upm.edu.my/id/eprint/109086/1/2023122923461007_MJMHS_0728.pdf |