Potential protein hydrolysates from the white and purple flower varieties of Orthosiphon aristatus leaves

This study was aimed to extract bioactive peptides from the white and purple flower varieties of Orthosiphon aristatus leaves. The herb is well known for its pharmacological importance, possibly attributed to its plant proteins. Phenol based extraction was used to extract plant proteins, and then hy...

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Main Authors: Chua, Lee Suan, Abdullah, Farah Izana, Lim, Teck Kwang, Lin, Qingsong
Format: Article
Published: Elsevier 2024
Online Access:http://psasir.upm.edu.my/id/eprint/109038/
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author Chua, Lee Suan
Abdullah, Farah Izana
Lim, Teck Kwang
Lin, Qingsong
author_facet Chua, Lee Suan
Abdullah, Farah Izana
Lim, Teck Kwang
Lin, Qingsong
author_sort Chua, Lee Suan
building UPM Institutional Repository
collection Online Access
description This study was aimed to extract bioactive peptides from the white and purple flower varieties of Orthosiphon aristatus leaves. The herb is well known for its pharmacological importance, possibly attributed to its plant proteins. Phenol based extraction was used to extract plant proteins, and then hydrolysed by proteolytic enzymes such as trypsin (serine protease) and pepsin (aspartic protease). MS/MS analysis revealed that 145 and 125 proteins were detected from the white and purple flower varieties, respectively. Trypsin hydrolysates were showed to have a higher degree of hydrolysis (24–33%), resulting in higher antioxidant and antibacterial activities. The white flower of trypsin hydrolysates showed a higher radical scavenging activity which could be attributed to its higher content of stress proteins (19%). However, trypsin hydrolysates from the purple flower showed higher ferric reducing power and bacterial growth inhibition. The performance of hydrolysates was better than ampicillin in inhibiting Acinetobacter baumanni and Staphylococcus aureus.
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institution Universiti Putra Malaysia
institution_category Local University
last_indexed 2025-11-15T14:01:59Z
publishDate 2024
publisher Elsevier
recordtype eprints
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spelling upm-1090382024-10-14T04:10:11Z http://psasir.upm.edu.my/id/eprint/109038/ Potential protein hydrolysates from the white and purple flower varieties of Orthosiphon aristatus leaves Chua, Lee Suan Abdullah, Farah Izana Lim, Teck Kwang Lin, Qingsong This study was aimed to extract bioactive peptides from the white and purple flower varieties of Orthosiphon aristatus leaves. The herb is well known for its pharmacological importance, possibly attributed to its plant proteins. Phenol based extraction was used to extract plant proteins, and then hydrolysed by proteolytic enzymes such as trypsin (serine protease) and pepsin (aspartic protease). MS/MS analysis revealed that 145 and 125 proteins were detected from the white and purple flower varieties, respectively. Trypsin hydrolysates were showed to have a higher degree of hydrolysis (24–33%), resulting in higher antioxidant and antibacterial activities. The white flower of trypsin hydrolysates showed a higher radical scavenging activity which could be attributed to its higher content of stress proteins (19%). However, trypsin hydrolysates from the purple flower showed higher ferric reducing power and bacterial growth inhibition. The performance of hydrolysates was better than ampicillin in inhibiting Acinetobacter baumanni and Staphylococcus aureus. Elsevier 2024-01-30 Article PeerReviewed Chua, Lee Suan and Abdullah, Farah Izana and Lim, Teck Kwang and Lin, Qingsong (2024) Potential protein hydrolysates from the white and purple flower varieties of Orthosiphon aristatus leaves. Food Chemistry, 432. art. no. 137261. pp. 1-8. ISSN 0308-8146 https://linkinghub.elsevier.com/retrieve/pii/S0308814623018794 10.1016/j.foodchem.2023.137261
spellingShingle Chua, Lee Suan
Abdullah, Farah Izana
Lim, Teck Kwang
Lin, Qingsong
Potential protein hydrolysates from the white and purple flower varieties of Orthosiphon aristatus leaves
title Potential protein hydrolysates from the white and purple flower varieties of Orthosiphon aristatus leaves
title_full Potential protein hydrolysates from the white and purple flower varieties of Orthosiphon aristatus leaves
title_fullStr Potential protein hydrolysates from the white and purple flower varieties of Orthosiphon aristatus leaves
title_full_unstemmed Potential protein hydrolysates from the white and purple flower varieties of Orthosiphon aristatus leaves
title_short Potential protein hydrolysates from the white and purple flower varieties of Orthosiphon aristatus leaves
title_sort potential protein hydrolysates from the white and purple flower varieties of orthosiphon aristatus leaves
url http://psasir.upm.edu.my/id/eprint/109038/
http://psasir.upm.edu.my/id/eprint/109038/
http://psasir.upm.edu.my/id/eprint/109038/