Chemical Constituents of Calophyllum Inophyllum and Cratoxylum Glaucum (Guttiferae)
Extensive studies on the plants, Calophyllum inophyllum and Cratoxylum glaucum have resulted in the isolation of ten compounds. All these compounds were isolated by means of chromatographic methods and their structures derived on the basis of spectroscopic evidence, mainly 1D and 2D nuclear magne...
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| Format: | Thesis |
| Language: | English English |
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2006
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| Online Access: | http://psasir.upm.edu.my/id/eprint/109/ http://psasir.upm.edu.my/id/eprint/109/1/549072_t_fs_2006_3.pdf |
| _version_ | 1848838670432337920 |
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| author | Kua, Audrey Siew May |
| author_facet | Kua, Audrey Siew May |
| author_sort | Kua, Audrey Siew May |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Extensive studies on the plants, Calophyllum inophyllum and Cratoxylum glaucum have
resulted in the isolation of ten compounds. All these compounds were isolated by means
of chromatographic methods and their structures derived on the basis of spectroscopic
evidence, mainly 1D and 2D nuclear magnetic resonance spectroscopy.
Chemical investigations on the root bark extracts of Calophyllum inophyllum has yielded
two new xanthones, inophyllin A and inophyllin B, three known xanthones,
brasilixanthone B, tovopyrifolin C, caloxanthone B, one triterpene, friedelin and one
triterpenoid, -sitosterol. Cratoxylum glaucum afforded two triterpenes, friedelin and
stigmasterol, two known anthraquinones, 1,8-dihydroxy-3-methoxy-6-methylanthraquinone
and vismiaquinone and a known xanthone, dimethylmangostin.
Cytotoxic assay was performed using CEM-SS Cell Line. All the crude extracts of
Calophyllum inophyllum and Cratoxylum glaucum showed no activity.
Antimicrobial assay was carried out towards four pathogenic bacteria, Methicillin
Resistant Staphylococcus aures, Pseudomonas aeruginosa, Staphylococcus typhimurium
and Bacillus subtilis. Most of the crude extracts tested against these microbes gave no
activity.
Larvicidal test was carried out towards the larvae of Aedes aegypti. The larvae were not
susceptible to all of the crude extracts and pure compounds of Calophyllum inophyllum
and Cratoxylum glaucum
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| first_indexed | 2025-11-15T06:59:15Z |
| format | Thesis |
| id | upm-109 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T06:59:15Z |
| publishDate | 2006 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1092013-05-27T06:45:37Z http://psasir.upm.edu.my/id/eprint/109/ Chemical Constituents of Calophyllum Inophyllum and Cratoxylum Glaucum (Guttiferae) Kua, Audrey Siew May Extensive studies on the plants, Calophyllum inophyllum and Cratoxylum glaucum have resulted in the isolation of ten compounds. All these compounds were isolated by means of chromatographic methods and their structures derived on the basis of spectroscopic evidence, mainly 1D and 2D nuclear magnetic resonance spectroscopy. Chemical investigations on the root bark extracts of Calophyllum inophyllum has yielded two new xanthones, inophyllin A and inophyllin B, three known xanthones, brasilixanthone B, tovopyrifolin C, caloxanthone B, one triterpene, friedelin and one triterpenoid, -sitosterol. Cratoxylum glaucum afforded two triterpenes, friedelin and stigmasterol, two known anthraquinones, 1,8-dihydroxy-3-methoxy-6-methylanthraquinone and vismiaquinone and a known xanthone, dimethylmangostin. Cytotoxic assay was performed using CEM-SS Cell Line. All the crude extracts of Calophyllum inophyllum and Cratoxylum glaucum showed no activity. Antimicrobial assay was carried out towards four pathogenic bacteria, Methicillin Resistant Staphylococcus aures, Pseudomonas aeruginosa, Staphylococcus typhimurium and Bacillus subtilis. Most of the crude extracts tested against these microbes gave no activity. Larvicidal test was carried out towards the larvae of Aedes aegypti. The larvae were not susceptible to all of the crude extracts and pure compounds of Calophyllum inophyllum and Cratoxylum glaucum 2006-01 Thesis NonPeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/109/1/549072_t_fs_2006_3.pdf Kua, Audrey Siew May (2006) Chemical Constituents of Calophyllum Inophyllum and Cratoxylum Glaucum (Guttiferae). Masters thesis, Universiti Putra Malaysia. Calophyllum inophyllum Guttiferae English |
| spellingShingle | Calophyllum inophyllum Guttiferae Kua, Audrey Siew May Chemical Constituents of Calophyllum Inophyllum and Cratoxylum Glaucum (Guttiferae) |
| title | Chemical Constituents of Calophyllum Inophyllum and Cratoxylum Glaucum (Guttiferae) |
| title_full | Chemical Constituents of Calophyllum Inophyllum and Cratoxylum Glaucum (Guttiferae) |
| title_fullStr | Chemical Constituents of Calophyllum Inophyllum and Cratoxylum Glaucum (Guttiferae) |
| title_full_unstemmed | Chemical Constituents of Calophyllum Inophyllum and Cratoxylum Glaucum (Guttiferae) |
| title_short | Chemical Constituents of Calophyllum Inophyllum and Cratoxylum Glaucum (Guttiferae) |
| title_sort | chemical constituents of calophyllum inophyllum and cratoxylum glaucum (guttiferae) |
| topic | Calophyllum inophyllum Guttiferae |
| url | http://psasir.upm.edu.my/id/eprint/109/ http://psasir.upm.edu.my/id/eprint/109/1/549072_t_fs_2006_3.pdf |