The importance of hypoxia sensors in detecting HIF-1 biomarker at high altitude
The episode of prolonged exposure to high altitude can cause hypoxia and potential significant health consequences. In people with high altitude disorder, the body reaction to high altitudes starts with the formation of a protein called hypoxia-inducible factor (HIF), which triggers a series of othe...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MedCrave Group
2023
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/108978/ http://psasir.upm.edu.my/id/eprint/108978/1/The%20importance%20of%20hypoxia%20sensors%20in%20detecting%20HIF-1%20biomarker%20at%20high%20altitude.pdf |
| _version_ | 1848865252362420224 |
|---|---|
| author | Shaharuddin, Shazreen Nik Abd Rahman, Nik Mohd Afizan Masarudin, Mas Jaffri N Alamassi, Mohammedarfat |
| author_facet | Shaharuddin, Shazreen Nik Abd Rahman, Nik Mohd Afizan Masarudin, Mas Jaffri N Alamassi, Mohammedarfat |
| author_sort | Shaharuddin, Shazreen |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | The episode of prolonged exposure to high altitude can cause hypoxia and potential significant health consequences. In people with high altitude disorder, the body reaction to high altitudes starts with the formation of a protein called hypoxia-inducible factor (HIF), which triggers a series of other physiological changes and plays a central role in the hypoxia response; its activity is regulated by the oxygen-dependent degradation of the HIF-1α protein. This deserving condition provides an opportunity to study the effect of low oxygen tension of flying at high altitude that could lead to hypoxia using hypoxia sensor. |
| first_indexed | 2025-11-15T14:01:45Z |
| format | Article |
| id | upm-108978 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T14:01:45Z |
| publishDate | 2023 |
| publisher | MedCrave Group |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1089782024-10-17T03:36:31Z http://psasir.upm.edu.my/id/eprint/108978/ The importance of hypoxia sensors in detecting HIF-1 biomarker at high altitude Shaharuddin, Shazreen Nik Abd Rahman, Nik Mohd Afizan Masarudin, Mas Jaffri N Alamassi, Mohammedarfat The episode of prolonged exposure to high altitude can cause hypoxia and potential significant health consequences. In people with high altitude disorder, the body reaction to high altitudes starts with the formation of a protein called hypoxia-inducible factor (HIF), which triggers a series of other physiological changes and plays a central role in the hypoxia response; its activity is regulated by the oxygen-dependent degradation of the HIF-1α protein. This deserving condition provides an opportunity to study the effect of low oxygen tension of flying at high altitude that could lead to hypoxia using hypoxia sensor. MedCrave Group 2023-10-19 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/108978/1/The%20importance%20of%20hypoxia%20sensors%20in%20detecting%20HIF-1%20biomarker%20at%20high%20altitude.pdf Shaharuddin, Shazreen and Nik Abd Rahman, Nik Mohd Afizan and Masarudin, Mas Jaffri and N Alamassi, Mohammedarfat (2023) The importance of hypoxia sensors in detecting HIF-1 biomarker at high altitude. Aeronautics and Aerospace Open Access Journal, 7 (4). 132- 133. ISSN 2576-4500 https://medcraveonline.com/AAOAJ/the-importance-of-hypoxia-sensors-in-detectinghif-1-biomarker-at-high-altitude.html 10.15406/aaoaj.2023.07.00182 |
| spellingShingle | Shaharuddin, Shazreen Nik Abd Rahman, Nik Mohd Afizan Masarudin, Mas Jaffri N Alamassi, Mohammedarfat The importance of hypoxia sensors in detecting HIF-1 biomarker at high altitude |
| title | The importance of hypoxia sensors in detecting HIF-1 biomarker at high altitude |
| title_full | The importance of hypoxia sensors in detecting HIF-1 biomarker at high altitude |
| title_fullStr | The importance of hypoxia sensors in detecting HIF-1 biomarker at high altitude |
| title_full_unstemmed | The importance of hypoxia sensors in detecting HIF-1 biomarker at high altitude |
| title_short | The importance of hypoxia sensors in detecting HIF-1 biomarker at high altitude |
| title_sort | importance of hypoxia sensors in detecting hif-1 biomarker at high altitude |
| url | http://psasir.upm.edu.my/id/eprint/108978/ http://psasir.upm.edu.my/id/eprint/108978/ http://psasir.upm.edu.my/id/eprint/108978/ http://psasir.upm.edu.my/id/eprint/108978/1/The%20importance%20of%20hypoxia%20sensors%20in%20detecting%20HIF-1%20biomarker%20at%20high%20altitude.pdf |