Revolutionizing cancer treatment by boosting dendritic cell vaccine efficacy with graphene oxide
Dendritic cells (DCs) are potent antigen presenting cells that play a crucial role in stimulating T cell responses against cancer. DC vaccines have been utilized as an immunotherapy approach for cancer treatment, but their effectiveness is hampered by challenges in the tumor microenvironment. Graphe...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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EnPress Publisher
2023
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| Online Access: | http://psasir.upm.edu.my/id/eprint/108811/ http://psasir.upm.edu.my/id/eprint/108811/1/Revolutionizing%20cancer%20treatment.pdf |
| _version_ | 1848865212491366400 |
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| author | Mohamed, Rafeezul Ramli, Muhammad Mahyiddin Reshak, Ali H. Osman, Nurul Huda Aziz, Mohd Yusmaidie Mansor, Mohd Syahir |
| author_facet | Mohamed, Rafeezul Ramli, Muhammad Mahyiddin Reshak, Ali H. Osman, Nurul Huda Aziz, Mohd Yusmaidie Mansor, Mohd Syahir |
| author_sort | Mohamed, Rafeezul |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Dendritic cells (DCs) are potent antigen presenting cells that play a crucial role in stimulating T cell responses against cancer. DC vaccines have been utilized as an immunotherapy approach for cancer treatment, but their effectiveness is hampered by challenges in the tumor microenvironment. Graphene oxide (GO), a cutting-edge carbon-based nanomaterial, has shown promise in modulating DC activation and function. This review highlights the recent advancements in DC vaccines and explores how GO can enhance their efficacy for cancer treatment. By leveraging the unique properties of GO, such as its biocompatibility and immunomodulatory effects, DC vaccines can potentially be optimized to overcome the limitations of the tumor microenvironment and achieve improved outcomes in cancer immunotherapy. |
| first_indexed | 2025-11-15T14:01:07Z |
| format | Article |
| id | upm-108811 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T14:01:07Z |
| publishDate | 2023 |
| publisher | EnPress Publisher |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1088112024-10-11T08:27:42Z http://psasir.upm.edu.my/id/eprint/108811/ Revolutionizing cancer treatment by boosting dendritic cell vaccine efficacy with graphene oxide Mohamed, Rafeezul Ramli, Muhammad Mahyiddin Reshak, Ali H. Osman, Nurul Huda Aziz, Mohd Yusmaidie Mansor, Mohd Syahir Dendritic cells (DCs) are potent antigen presenting cells that play a crucial role in stimulating T cell responses against cancer. DC vaccines have been utilized as an immunotherapy approach for cancer treatment, but their effectiveness is hampered by challenges in the tumor microenvironment. Graphene oxide (GO), a cutting-edge carbon-based nanomaterial, has shown promise in modulating DC activation and function. This review highlights the recent advancements in DC vaccines and explores how GO can enhance their efficacy for cancer treatment. By leveraging the unique properties of GO, such as its biocompatibility and immunomodulatory effects, DC vaccines can potentially be optimized to overcome the limitations of the tumor microenvironment and achieve improved outcomes in cancer immunotherapy. EnPress Publisher 2023-07-17 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/108811/1/Revolutionizing%20cancer%20treatment.pdf Mohamed, Rafeezul and Ramli, Muhammad Mahyiddin and Reshak, Ali H. and Osman, Nurul Huda and Aziz, Mohd Yusmaidie and Mansor, Mohd Syahir (2023) Revolutionizing cancer treatment by boosting dendritic cell vaccine efficacy with graphene oxide. Trends in Immunotherapy, 7 (1). art. no. 2039. pp. 1-13. ISSN 2573-5985 https://systems.enpress-publisher.com/index.php/ti/article/view/2039 10.24294/ti.v7.i1.2039 |
| spellingShingle | Mohamed, Rafeezul Ramli, Muhammad Mahyiddin Reshak, Ali H. Osman, Nurul Huda Aziz, Mohd Yusmaidie Mansor, Mohd Syahir Revolutionizing cancer treatment by boosting dendritic cell vaccine efficacy with graphene oxide |
| title | Revolutionizing cancer treatment by boosting dendritic cell vaccine efficacy with graphene oxide |
| title_full | Revolutionizing cancer treatment by boosting dendritic cell vaccine efficacy with graphene oxide |
| title_fullStr | Revolutionizing cancer treatment by boosting dendritic cell vaccine efficacy with graphene oxide |
| title_full_unstemmed | Revolutionizing cancer treatment by boosting dendritic cell vaccine efficacy with graphene oxide |
| title_short | Revolutionizing cancer treatment by boosting dendritic cell vaccine efficacy with graphene oxide |
| title_sort | revolutionizing cancer treatment by boosting dendritic cell vaccine efficacy with graphene oxide |
| url | http://psasir.upm.edu.my/id/eprint/108811/ http://psasir.upm.edu.my/id/eprint/108811/ http://psasir.upm.edu.my/id/eprint/108811/ http://psasir.upm.edu.my/id/eprint/108811/1/Revolutionizing%20cancer%20treatment.pdf |