The NLRP3 inflammasome in age-related cerebral small vessel disease manifestations: untying the innate immune response connection

QR Code

The NLRP3 inflammasome in age-related cerebral small vessel disease manifestations: untying the innate immune response connection

In this narrative review, we present the evidence on nucleotide-binding and oligomerization (NOD) domain-like receptor (NLR) family pyrin domain (PYD)-containing 3 (NLRP3) inflammasome activation for its putative roles in the elusive pathomechanism of aging-related cerebral small vessel disease (CSV...

Full description

Bibliographic Details
Main Authors:	Che Mohd Nassir, Che Mohd Nasril, Damodaran, Thenmoly, Ismail, Nurul Iman, Hashim, Sabarisah, Jaffer, Usman, Hamid, Hafizah Abdul, Mehat, Muhammad Zulfadli, Norazit, Anwar, Mustapha, Muzaimi
Format:	Article
Language:	English
Published:	Multidisciplinary Digital Publishing Institute 2023
Online Access:	http://psasir.upm.edu.my/id/eprint/108690/ http://psasir.upm.edu.my/id/eprint/108690/1/The%20NLRP3%20inflammasome%20in%20age-related%20cerebral.pdf

Similar Items

Neuroinflammation and COVID-19 ischemic stroke recovery—Evolving evidence for the mediating roles of the ACE2/Angiotensin-(1–7)/Mas Receptor Axis and NLRP3 Inflammasome
by: Che Mohd Nasril, Che Mohd Nassir, et al.
Published: (2022)

Is cerebral small vessel disease a central nervous system interstitial fluidopathy?
by: Abdul Hamid, Hafizah, et al.
Published: (2024)

Neuroinﬂammation and COVID-19 ischemic stroke recovery—Evolving evidence for the mediating roles of the ACE2/angiotensin-(1–7)/mas receptor axis and NLRP3 inﬂammasome
by: Che Mohd Nasril, Che Mohd Nassir, et al.
Published: (2022)

Neuroinflammation and COVID-19 ischemic stroke recovery —evolving evidence for the mediating roles of ACE2/angiotensin-1a“7/Mas receptor axis and NLRP3 inflammasome
by: Che Mohd Nassir, Che Mohd Nasril, et al.
Published: (2022)

Diabetic cardiac autonomic neuropathy: a review of NLRP3 inflammasome complicity
by: Subramaniam, Shamala Devi, et al.
Published: (2024)

Mitochondrial redox modulation of NLRP3 inflammasome in differentiated THP-1 cells
by: Abas, Razif, et al.
Published: (2019)

Neuroprotective potentials of honey for cerebral small vessel disease
by: Che Mohd Nassir, Che Mohd Nasril, et al.
Published: (2022)

Cerebral small vessel disease (CSVD) – lessons from the animal models
by: Mustapha, Muzaimi, et al.
Published: (2019)

Menhaden fish oil attenuates postpartum depression in rat model via inhibition of NLRP3-inflammasome driven inflammatory pathway
by: Abdul Aziz, Nurul Uyun, et al.
Published: (2021)

Exploratory longitudinal studies on cerebral small vessel disease (CSVD) in apparently asymptomatic individuals with neuropsychological, neuroimaging and microparticles profiling
by: Nassir, Che Mohd Nasril Che Mohd
Published: (2018)

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1ß 2 in type 2 diabetes
by: Masters, S., et al.
Published: (2010)

Aberrant blood brain barrier dynamics in cerebral small vessel disease - a review of associations, pathomechanisms and therapeutic potentials
by: Zul Ramli, Sayyidah Maryamul Azra’, et al.
Published: (2024)

Studies Of Clitoria Ternatea Linn. Root Extract On Behavioural Effects And In Vivo Hippocampal Synaptic Plasticity In A Rat Model Of Chronic Cerebral Hypoperfusion
by: Damodaran, Thenmoly K
Published: (2018)

Activation of the inflammasome in bovine mammary macrophages by Streptococcus uberis
by: Tomes, Abbie
Published: (2024)

Neurological sequelae of post-COVID-19 fatigue: a narrative review of dipeptidyl peptidase IV-mediated cerebrovascular complications
by: Che Mohd Nassir, Che Mohd Nasril, et al.
Published: (2024)

Experimenting with Innate Immunity
by: Twycross, Jamie, et al.
Published: (2006)

Untying the Kibaran knot: a reassessment of Mesoproterozoic correlations in southern Africa based on SHRIMP U-Pb data from the Irumide belt
by: De Waele, Bert, et al.
Published: (2003)

An investigation into inflammasome-gene expression profile and genome-wide genotype data in gout
by: Sandoval-Plata, Gabriela
Published: (2022)

Libtissue - Implementing Innate Immunity
by: Twycross, Jamie, et al.
Published: (2006)

HDL in innate and adaptive immunity
by: Catapano, A., et al.
Published: (2014)

Comparison of super resolution methods in magnetic resonance images for small animals
by: Than, Joel Chia Ming, et al.
Published: (2019)

Estimating retinal vessel diameter change from the vessel cross-section
by: Che Azemin, Mohd Zulfaezal, et al.
Published: (2011)

Peculiarities of innate immune memory in crustaceans
by: Chen, Fei Low, et al.
Published: (2020)

Manoeuvring prediction of offshore supply vessel
by: Che Wan Othman, Che Wan Mohd. Noor
Published: (2009)

Airway epithelial barrier, mucins and inflammasome in distinct eosinophilic, neutrophilic and mixed inflammatory phenotypes of asthma
by: Tze, Tan Hern
Published: (2018)

Nature's manifestation
by: Mohd Yusof, Mohd Johari
Published: (2011)

Manifestation of nature
by: Shahidan, Mohd Fairuz
Published: (2013)

'Towards a Conceptual Framework for Innate Immunity'
by: Twycross, Jamie, et al.
Published: (2005)

Mammalian chitotriosidase and its role in innate immunity
by: Hall, Andrew J.
Published: (2009)

Integrating Innate and Adaptive Immunity for Intrusion Detection
by: Tedesco, Gianni, et al.
Published: (2006)

Sensing Danger: Innate Immunology for Intrusion Detection
by: Aickelin, Uwe, et al.
Published: (2007)

'Towards a Conceptual Framework for Innate Immunity'
by: Twycross, Jamie, et al.
Published: (2005)

Innate immune recognition of Neisseria meningitidis at the nasopharynx‎
by: Albiheyri, Raed
Published: (2016)

Innate and adaptive immune evasion by dengue virus
by: Lee, Michelle Felicia *, et al.
Published: (2022)

Reflections on neuroethical issues in neuroimaging research advances from the Islamic perspective
by: Nurfaizatul Aisyah Ab Aziz,, et al.
Published: (2024)

Vessel
by: Pendal, Simon
Published: (2017)

Serum marker of inflammasome activity correlates with liver injury in nonalcoholic fatty liver disease and is influenced by genetic polymorphisms
by: Adams, L., et al.
Published: (2015)

AIM2 Inflammasome-Mediated Pyroptosis in Enterovirus A71-Infected Neuronal Cells Restricts Viral Replication
by: Yogarajah, Thinesshwary, et al.
Published: (2017)

Supervised vessel segmentation with minimal features
by: Che Azemin, Mohd Zulfaezal, et al.
Published: (2014)

Characterisation of the Innate Immune Responses of Marron (Cherax cainii)
by: Prastowo, Bambang Widyo
Published: (2017)