Flowability properties of binary powder mixtures containing dates powder (Pheonix dactylifera) mixed with lactose monohydrate and microcrystalline cellulose based excipients
Powder flow is important in powder processing industries to obtain a quality by design product and efficient manufacturing process. Poor powder flowability can cause problems especially during high speed tableting and capsule filling processes. In this study, dates powder (DP), lactose monohydrate p...
| Main Authors: | , , , , , |
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| Format: | Article |
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Penerbit UTM Press
2023
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| Online Access: | http://psasir.upm.edu.my/id/eprint/108027/ |
| _version_ | 1848865053976035328 |
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| author | Ahmad Hamidi, Fara Wahida Anuar, Mohd Shamsul Baharuddin, Azhari Samsu P. Mohammed, Mohd Afandi Naim, Mohd Nazli Mohd Tahir, Suraya |
| author_facet | Ahmad Hamidi, Fara Wahida Anuar, Mohd Shamsul Baharuddin, Azhari Samsu P. Mohammed, Mohd Afandi Naim, Mohd Nazli Mohd Tahir, Suraya |
| author_sort | Ahmad Hamidi, Fara Wahida |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Powder flow is important in powder processing industries to obtain a quality by design product and efficient manufacturing process. Poor powder flowability can cause problems especially during high speed tableting and capsule filling processes. In this study, dates powder (DP), lactose monohydrate powder, and two types of microcrystalline-based powder excipients evaluated for their flow properties as a binary mixture. Angle of repose (AoR), Hausner ratio (HR) and Carr index (CI) were used to characterize the extent of the powder cohesion. The results show that generally, as particle size increases, values of AoR generally decreases, depicting lower flowability characteristics with decreasing binary mixture particle size. However, HR and CI flowability indicators give contrasting flowability characteristics for the binary mixture containing lactose monohydrate and dates powder. |
| first_indexed | 2025-11-15T13:58:36Z |
| format | Article |
| id | upm-108027 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T13:58:36Z |
| publishDate | 2023 |
| publisher | Penerbit UTM Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1080272024-09-26T04:00:56Z http://psasir.upm.edu.my/id/eprint/108027/ Flowability properties of binary powder mixtures containing dates powder (Pheonix dactylifera) mixed with lactose monohydrate and microcrystalline cellulose based excipients Ahmad Hamidi, Fara Wahida Anuar, Mohd Shamsul Baharuddin, Azhari Samsu P. Mohammed, Mohd Afandi Naim, Mohd Nazli Mohd Tahir, Suraya Powder flow is important in powder processing industries to obtain a quality by design product and efficient manufacturing process. Poor powder flowability can cause problems especially during high speed tableting and capsule filling processes. In this study, dates powder (DP), lactose monohydrate powder, and two types of microcrystalline-based powder excipients evaluated for their flow properties as a binary mixture. Angle of repose (AoR), Hausner ratio (HR) and Carr index (CI) were used to characterize the extent of the powder cohesion. The results show that generally, as particle size increases, values of AoR generally decreases, depicting lower flowability characteristics with decreasing binary mixture particle size. However, HR and CI flowability indicators give contrasting flowability characteristics for the binary mixture containing lactose monohydrate and dates powder. Penerbit UTM Press 2023 Article PeerReviewed Ahmad Hamidi, Fara Wahida and Anuar, Mohd Shamsul and Baharuddin, Azhari Samsu and P. Mohammed, Mohd Afandi and Naim, Mohd Nazli and Mohd Tahir, Suraya (2023) Flowability properties of binary powder mixtures containing dates powder (Pheonix dactylifera) mixed with lactose monohydrate and microcrystalline cellulose based excipients. ASEAN Engineering Journal, 13 (4). pp. 13-18. ISSN 2586-9159 https://journals.utm.my/aej/article/view/18784 10.11113/aej.v13.18784 |
| spellingShingle | Ahmad Hamidi, Fara Wahida Anuar, Mohd Shamsul Baharuddin, Azhari Samsu P. Mohammed, Mohd Afandi Naim, Mohd Nazli Mohd Tahir, Suraya Flowability properties of binary powder mixtures containing dates powder (Pheonix dactylifera) mixed with lactose monohydrate and microcrystalline cellulose based excipients |
| title | Flowability properties of binary powder mixtures containing dates powder (Pheonix dactylifera) mixed with lactose monohydrate and microcrystalline cellulose based excipients |
| title_full | Flowability properties of binary powder mixtures containing dates powder (Pheonix dactylifera) mixed with lactose monohydrate and microcrystalline cellulose based excipients |
| title_fullStr | Flowability properties of binary powder mixtures containing dates powder (Pheonix dactylifera) mixed with lactose monohydrate and microcrystalline cellulose based excipients |
| title_full_unstemmed | Flowability properties of binary powder mixtures containing dates powder (Pheonix dactylifera) mixed with lactose monohydrate and microcrystalline cellulose based excipients |
| title_short | Flowability properties of binary powder mixtures containing dates powder (Pheonix dactylifera) mixed with lactose monohydrate and microcrystalline cellulose based excipients |
| title_sort | flowability properties of binary powder mixtures containing dates powder (pheonix dactylifera) mixed with lactose monohydrate and microcrystalline cellulose based excipients |
| url | http://psasir.upm.edu.my/id/eprint/108027/ http://psasir.upm.edu.my/id/eprint/108027/ http://psasir.upm.edu.my/id/eprint/108027/ |