Establishing cut-off points for consistency in reporting hypoglycemia symptoms among diabetes patients

Recognizing the onset of hypoglycemia is crucial for managing its effects in diabetes patients, but the variability of symptoms makes accurate reporting challenging. This study is aimed to establish cut-off points for differentiating consistent and inconsistent symptom reporting during hypoglycemic...

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Main Authors: Sharmin, Afsana Al, Zulkafli, Hani Syahida, Mohamed Ali, Nazihah
Format: Article
Published: Pushpa Publishing House 2023
Online Access:http://psasir.upm.edu.my/id/eprint/107746/
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author Sharmin, Afsana Al
Zulkafli, Hani Syahida
Mohamed Ali, Nazihah
author_facet Sharmin, Afsana Al
Zulkafli, Hani Syahida
Mohamed Ali, Nazihah
author_sort Sharmin, Afsana Al
building UPM Institutional Repository
collection Online Access
description Recognizing the onset of hypoglycemia is crucial for managing its effects in diabetes patients, but the variability of symptoms makes accurate reporting challenging. This study is aimed to establish cut-off points for differentiating consistent and inconsistent symptom reporting during hypoglycemic episodes among diabetes patients. The study utilized data collected by the UK Hypoglycemia Study Group, comprising 26 symptoms reported by 66 diabetes patients during 2791 episodes of hypoglycemia. A Bayesian consistency model was developed to assess individual symptom consistency during episodes. The estimated consistency values were assumed to follow a beta distribution between 0 and 1, and the regularized incomplete beta function was used to determine cut-off points. The analysis revealed significant variability in symptom reporting both within episodes and between patients. Using the assumed distribution and the method of moments estimation, cut-off points were established to categorize patients into low (0 to 0.44), medium (0.44 to 0.60), and high (0.60 to 1) consistency levels. Approximately 35 of the patients demonstrated a high level of consistency, while the majority exhibited lower consistency in reporting symptoms. The classification of consistencies from an assumed distribution provides meaningful and relevant cut-off points, enabling a more accurate differentiation between reporting of consistent and inconsistent symptoms. The results contribute to improving the understanding of symptom variability and can aid in personalized treatment approaches for diabetes patients.
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institution Universiti Putra Malaysia
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spelling upm-1077462024-07-17T07:12:01Z http://psasir.upm.edu.my/id/eprint/107746/ Establishing cut-off points for consistency in reporting hypoglycemia symptoms among diabetes patients Sharmin, Afsana Al Zulkafli, Hani Syahida Mohamed Ali, Nazihah Recognizing the onset of hypoglycemia is crucial for managing its effects in diabetes patients, but the variability of symptoms makes accurate reporting challenging. This study is aimed to establish cut-off points for differentiating consistent and inconsistent symptom reporting during hypoglycemic episodes among diabetes patients. The study utilized data collected by the UK Hypoglycemia Study Group, comprising 26 symptoms reported by 66 diabetes patients during 2791 episodes of hypoglycemia. A Bayesian consistency model was developed to assess individual symptom consistency during episodes. The estimated consistency values were assumed to follow a beta distribution between 0 and 1, and the regularized incomplete beta function was used to determine cut-off points. The analysis revealed significant variability in symptom reporting both within episodes and between patients. Using the assumed distribution and the method of moments estimation, cut-off points were established to categorize patients into low (0 to 0.44), medium (0.44 to 0.60), and high (0.60 to 1) consistency levels. Approximately 35 of the patients demonstrated a high level of consistency, while the majority exhibited lower consistency in reporting symptoms. The classification of consistencies from an assumed distribution provides meaningful and relevant cut-off points, enabling a more accurate differentiation between reporting of consistent and inconsistent symptoms. The results contribute to improving the understanding of symptom variability and can aid in personalized treatment approaches for diabetes patients. Pushpa Publishing House 2023-11-22 Article PeerReviewed Sharmin, Afsana Al and Zulkafli, Hani Syahida and Mohamed Ali, Nazihah (2023) Establishing cut-off points for consistency in reporting hypoglycemia symptoms among diabetes patients. JP Journal of Biostatistics, 24 (1). pp. 31-46. ISSN 0973-5143 https://pphmjopenaccess.com/index.php/jpjb/article/view/1169 10.17654/0973514324004
spellingShingle Sharmin, Afsana Al
Zulkafli, Hani Syahida
Mohamed Ali, Nazihah
Establishing cut-off points for consistency in reporting hypoglycemia symptoms among diabetes patients
title Establishing cut-off points for consistency in reporting hypoglycemia symptoms among diabetes patients
title_full Establishing cut-off points for consistency in reporting hypoglycemia symptoms among diabetes patients
title_fullStr Establishing cut-off points for consistency in reporting hypoglycemia symptoms among diabetes patients
title_full_unstemmed Establishing cut-off points for consistency in reporting hypoglycemia symptoms among diabetes patients
title_short Establishing cut-off points for consistency in reporting hypoglycemia symptoms among diabetes patients
title_sort establishing cut-off points for consistency in reporting hypoglycemia symptoms among diabetes patients
url http://psasir.upm.edu.my/id/eprint/107746/
http://psasir.upm.edu.my/id/eprint/107746/
http://psasir.upm.edu.my/id/eprint/107746/