Environmental impacts, exposure pathways, and health effects of PFOA and PFOS
Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals that have been widely utilized in various industries since the 1940s, and have now emerged as environmental contaminants. In recent years, perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) have been restricted and re...
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| Format: | Article |
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Elsevier
2023
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| Online Access: | http://psasir.upm.edu.my/id/eprint/107724/ |
| _version_ | 1848864973594296320 |
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| author | Wee, Sze Yee Aris, Ahmad Zaharin |
| author_facet | Wee, Sze Yee Aris, Ahmad Zaharin |
| author_sort | Wee, Sze Yee |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals that have been widely utilized in various industries since the 1940s, and have now emerged as environmental contaminants. In recent years, perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) have been restricted and replaced with several alternatives. The high persistence, bioaccumulation, and toxicity of these substances have contributed to their emergence as environmental contaminants, and several aspects of their behavior remain largely unknown and require further investigation. The trace level of PFAS makes the development of a monitoring database challenging. Additionally, the potential health issues associated with PFAS are not yet fully understood due to ongoing research and inadequate evidence (experimental and epidemiological studies), especially with regard to the combined effects of exposure to PFAS mixtures and human health risks from drinking water consumption. This in-depth review offers unprecedented insights into the exposure pathways and toxicological impacts of PFAS, addressing critical knowledge gaps in their behaviors and health implications. It presents a comprehensive NABC”Needs, Approach, Benefits, and Challenges”analysis to guide future strategies for the sustainable monitoring and management of these pervasive environmental contaminants. |
| first_indexed | 2025-11-15T13:57:19Z |
| format | Article |
| id | upm-107724 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T13:57:19Z |
| publishDate | 2023 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1077242024-10-28T02:55:34Z http://psasir.upm.edu.my/id/eprint/107724/ Environmental impacts, exposure pathways, and health effects of PFOA and PFOS Wee, Sze Yee Aris, Ahmad Zaharin Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals that have been widely utilized in various industries since the 1940s, and have now emerged as environmental contaminants. In recent years, perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) have been restricted and replaced with several alternatives. The high persistence, bioaccumulation, and toxicity of these substances have contributed to their emergence as environmental contaminants, and several aspects of their behavior remain largely unknown and require further investigation. The trace level of PFAS makes the development of a monitoring database challenging. Additionally, the potential health issues associated with PFAS are not yet fully understood due to ongoing research and inadequate evidence (experimental and epidemiological studies), especially with regard to the combined effects of exposure to PFAS mixtures and human health risks from drinking water consumption. This in-depth review offers unprecedented insights into the exposure pathways and toxicological impacts of PFAS, addressing critical knowledge gaps in their behaviors and health implications. It presents a comprehensive NABC”Needs, Approach, Benefits, and Challenges”analysis to guide future strategies for the sustainable monitoring and management of these pervasive environmental contaminants. Elsevier 2023-11-15 Article PeerReviewed Wee, Sze Yee and Aris, Ahmad Zaharin (2023) Environmental impacts, exposure pathways, and health effects of PFOA and PFOS. Ecotoxicology and Environmental Safety, 267. art. no. 115663. pp. 1-15. ISSN 0147-6513; eISSN: 1090-2414 https://linkinghub.elsevier.com/retrieve/pii/S0147651323011673 10.1016/j.ecoenv.2023.115663 |
| spellingShingle | Wee, Sze Yee Aris, Ahmad Zaharin Environmental impacts, exposure pathways, and health effects of PFOA and PFOS |
| title | Environmental impacts, exposure pathways, and health effects of PFOA and PFOS |
| title_full | Environmental impacts, exposure pathways, and health effects of PFOA and PFOS |
| title_fullStr | Environmental impacts, exposure pathways, and health effects of PFOA and PFOS |
| title_full_unstemmed | Environmental impacts, exposure pathways, and health effects of PFOA and PFOS |
| title_short | Environmental impacts, exposure pathways, and health effects of PFOA and PFOS |
| title_sort | environmental impacts, exposure pathways, and health effects of pfoa and pfos |
| url | http://psasir.upm.edu.my/id/eprint/107724/ http://psasir.upm.edu.my/id/eprint/107724/ http://psasir.upm.edu.my/id/eprint/107724/ |