Effect of carcinomas on autosomal trait screening: a review article
This review highlights the effect of carcinomas on the results of the examination of autosomal genetic traits for identification and paternity tests when carcinoid tissue is the only source and no other samples are available. In DNA typing or genetic fingerprinting, variable elements are isolated an...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Multidisciplinary Digital Publishing Institute
2023
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| Online Access: | http://psasir.upm.edu.my/id/eprint/107484/ http://psasir.upm.edu.my/id/eprint/107484/1/Effect%20of%20Carcinomas%20on%20Autosomal%20Trait%20Screening%20A%20Review%20Article.pdf |
| _version_ | 1848864908360286208 |
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| author | Alhatim, Husein Abdullah, Muhammad Nazrul Hakim Abu Bakar, Suhaili Amer, Sayed Amin |
| author_facet | Alhatim, Husein Abdullah, Muhammad Nazrul Hakim Abu Bakar, Suhaili Amer, Sayed Amin |
| author_sort | Alhatim, Husein |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | This review highlights the effect of carcinomas on the results of the examination of autosomal genetic traits for identification and paternity tests when carcinoid tissue is the only source and no other samples are available. In DNA typing or genetic fingerprinting, variable elements are isolated and identified within the base pair sequences that form the DNA. The person’s probable identity can be determined by analysing nucleotide sequences in particular regions of DNA unique to everyone. Genetics plays an increasingly important role in the risk stratification and management of carcinoma patients. The available information from previous studies has indicated that in some incidents, including mass disasters and crimes such as terrorist incidents, biological evidence may not be available at the scene of the accident, except for some unknown human remains found in the form of undefined human tissues. If these tissues have cancerous tumours, it may affect the examination of the genetic traits derived from these samples, thereby resulting in a failure to identify the person. Pathology units, more often, verify the identity of the patients who were diagnosed with cancer in reference to their deceased tumorous relatives. Genetic fingerprinting (GF) is also used in paternity testing when the alleged parent disappeared or died and earlier was diagnosed and treated for cancer. |
| first_indexed | 2025-11-15T13:56:17Z |
| format | Article |
| id | upm-107484 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T13:56:17Z |
| publishDate | 2023 |
| publisher | Multidisciplinary Digital Publishing Institute |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1074842024-10-17T07:42:03Z http://psasir.upm.edu.my/id/eprint/107484/ Effect of carcinomas on autosomal trait screening: a review article Alhatim, Husein Abdullah, Muhammad Nazrul Hakim Abu Bakar, Suhaili Amer, Sayed Amin This review highlights the effect of carcinomas on the results of the examination of autosomal genetic traits for identification and paternity tests when carcinoid tissue is the only source and no other samples are available. In DNA typing or genetic fingerprinting, variable elements are isolated and identified within the base pair sequences that form the DNA. The person’s probable identity can be determined by analysing nucleotide sequences in particular regions of DNA unique to everyone. Genetics plays an increasingly important role in the risk stratification and management of carcinoma patients. The available information from previous studies has indicated that in some incidents, including mass disasters and crimes such as terrorist incidents, biological evidence may not be available at the scene of the accident, except for some unknown human remains found in the form of undefined human tissues. If these tissues have cancerous tumours, it may affect the examination of the genetic traits derived from these samples, thereby resulting in a failure to identify the person. Pathology units, more often, verify the identity of the patients who were diagnosed with cancer in reference to their deceased tumorous relatives. Genetic fingerprinting (GF) is also used in paternity testing when the alleged parent disappeared or died and earlier was diagnosed and treated for cancer. Multidisciplinary Digital Publishing Institute 2023-09-04 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/107484/1/Effect%20of%20Carcinomas%20on%20Autosomal%20Trait%20Screening%20A%20Review%20Article.pdf Alhatim, Husein and Abdullah, Muhammad Nazrul Hakim and Abu Bakar, Suhaili and Amer, Sayed Amin (2023) Effect of carcinomas on autosomal trait screening: a review article. Current Issues in Molecular Biology, 45 (9). pp. 7275-7285. ISSN 1467-3037; ESSN: 1467-3045 https://www.mdpi.com/1467-3045/45/9/460 10.3390/cimb45090460 |
| spellingShingle | Alhatim, Husein Abdullah, Muhammad Nazrul Hakim Abu Bakar, Suhaili Amer, Sayed Amin Effect of carcinomas on autosomal trait screening: a review article |
| title | Effect of carcinomas on autosomal trait screening: a review article |
| title_full | Effect of carcinomas on autosomal trait screening: a review article |
| title_fullStr | Effect of carcinomas on autosomal trait screening: a review article |
| title_full_unstemmed | Effect of carcinomas on autosomal trait screening: a review article |
| title_short | Effect of carcinomas on autosomal trait screening: a review article |
| title_sort | effect of carcinomas on autosomal trait screening: a review article |
| url | http://psasir.upm.edu.my/id/eprint/107484/ http://psasir.upm.edu.my/id/eprint/107484/ http://psasir.upm.edu.my/id/eprint/107484/ http://psasir.upm.edu.my/id/eprint/107484/1/Effect%20of%20Carcinomas%20on%20Autosomal%20Trait%20Screening%20A%20Review%20Article.pdf |