Comparative genomics analysis of Ganoderma orthologs involved in plant-pathogenesis
Ganoderma species are producers of bioactive secondary metabolites and lignin degraders. A few Ganoderma species are known to be plant pathogens that attack economically important trees. In this study, comparative genomics analysis was conducted on the proteome of ten Ganoderma species/strains, focu...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Multidisciplinary Digital Publishing Institute
2023
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/107078/ http://psasir.upm.edu.my/id/eprint/107078/1/Comparative%20genomics%20analysis%20of%20Ganoderma%20orthologs%20involved%20in%20plant-pathogenesis.pdf |
| _version_ | 1848864859330969600 |
|---|---|
| author | Ho, Chai-Ling |
| author_facet | Ho, Chai-Ling |
| author_sort | Ho, Chai-Ling |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Ganoderma species are producers of bioactive secondary metabolites and lignin degraders. A few Ganoderma species are known to be plant pathogens that attack economically important trees. In this study, comparative genomics analysis was conducted on the proteome of ten Ganoderma species/strains, focusing on the proteins that have been reported to be involved in plant-pathogenesis in other fungi. Fungal trophic lifestyle prediction of these Ganoderma species/strains supported that G. boninense (a potent pathogen to oil palm) is a hemibiotrophic fungus while the other Ganoderma species/strains analyzed were predicted to be saprophytes or a symbiont based on their Carbohydrate-Active Enzyme (CAZyme) contents. Although these Ganoderma species/strains were demonstrated to share many CAZymes and secondary metabolite core gene clusters, individual species may produce unique CAZymes and secondary metabolite core genes that determine their lifestyles, host-specificity, and potential as a producer of bioactive secondary metabolites. Ortholog groups that are related to fungal virulence from seven Ganoderma species/strains including those involved in lignin degradation, mycotoxin, siderophore and ergosterol biosynthesis, and virulence were summarized. Potential effectors were predicted from the proteome of these Ganoderma species/strains, and putative effectors that were being expressed in G. boninense in oil palm roots but not found in other species were identified. The findings provide a useful resource to further analyze plant-pathogenesis and wood degradation activities of these Ganoderma species. |
| first_indexed | 2025-11-15T13:55:30Z |
| format | Article |
| id | upm-107078 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T13:55:30Z |
| publishDate | 2023 |
| publisher | Multidisciplinary Digital Publishing Institute |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1070782024-10-17T07:06:11Z http://psasir.upm.edu.my/id/eprint/107078/ Comparative genomics analysis of Ganoderma orthologs involved in plant-pathogenesis Ho, Chai-Ling Ganoderma species are producers of bioactive secondary metabolites and lignin degraders. A few Ganoderma species are known to be plant pathogens that attack economically important trees. In this study, comparative genomics analysis was conducted on the proteome of ten Ganoderma species/strains, focusing on the proteins that have been reported to be involved in plant-pathogenesis in other fungi. Fungal trophic lifestyle prediction of these Ganoderma species/strains supported that G. boninense (a potent pathogen to oil palm) is a hemibiotrophic fungus while the other Ganoderma species/strains analyzed were predicted to be saprophytes or a symbiont based on their Carbohydrate-Active Enzyme (CAZyme) contents. Although these Ganoderma species/strains were demonstrated to share many CAZymes and secondary metabolite core gene clusters, individual species may produce unique CAZymes and secondary metabolite core genes that determine their lifestyles, host-specificity, and potential as a producer of bioactive secondary metabolites. Ortholog groups that are related to fungal virulence from seven Ganoderma species/strains including those involved in lignin degradation, mycotoxin, siderophore and ergosterol biosynthesis, and virulence were summarized. Potential effectors were predicted from the proteome of these Ganoderma species/strains, and putative effectors that were being expressed in G. boninense in oil palm roots but not found in other species were identified. The findings provide a useful resource to further analyze plant-pathogenesis and wood degradation activities of these Ganoderma species. Multidisciplinary Digital Publishing Institute 2023-03-22 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/107078/1/Comparative%20genomics%20analysis%20of%20Ganoderma%20orthologs%20involved%20in%20plant-pathogenesis.pdf Ho, Chai-Ling (2023) Comparative genomics analysis of Ganoderma orthologs involved in plant-pathogenesis. Forests, 14 (3). art. no. 653. pp. 1-20. ISSN 1999-4907 https://www.mdpi.com/1999-4907/14/3/653 10.3390/f14030653 |
| spellingShingle | Ho, Chai-Ling Comparative genomics analysis of Ganoderma orthologs involved in plant-pathogenesis |
| title | Comparative genomics analysis of Ganoderma orthologs involved in plant-pathogenesis |
| title_full | Comparative genomics analysis of Ganoderma orthologs involved in plant-pathogenesis |
| title_fullStr | Comparative genomics analysis of Ganoderma orthologs involved in plant-pathogenesis |
| title_full_unstemmed | Comparative genomics analysis of Ganoderma orthologs involved in plant-pathogenesis |
| title_short | Comparative genomics analysis of Ganoderma orthologs involved in plant-pathogenesis |
| title_sort | comparative genomics analysis of ganoderma orthologs involved in plant-pathogenesis |
| url | http://psasir.upm.edu.my/id/eprint/107078/ http://psasir.upm.edu.my/id/eprint/107078/ http://psasir.upm.edu.my/id/eprint/107078/ http://psasir.upm.edu.my/id/eprint/107078/1/Comparative%20genomics%20analysis%20of%20Ganoderma%20orthologs%20involved%20in%20plant-pathogenesis.pdf |