Collateral damage of COVID-19: late presentation of cerebrovascular accident

Coronavirus disease 2019 (COVID-19) is associated with an increased risk of death due to the sequelae of inflammation and thrombosis. Patients infected with COVID-19 are at risk of ischemic stroke due to the effects of inflammatory cytokine storm, platelet activation, endothelial dysfunction and pro...

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Main Authors: Ismail, Hazwani, Wan Zul Haikal Hafiz, Md Pauzi, Ahmad Luqman, Chao, Loh Wei, Yin, Lau Su
Format: Article
Language:English
Published: Malaysian Medical Association 2023
Online Access:http://psasir.upm.edu.my/id/eprint/107055/
http://psasir.upm.edu.my/id/eprint/107055/1/Collateral%20damage%20of%20COVID-19_late%20presentation%20of%20cerebrovascular%20accident.pdf
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author Ismail, Hazwani
Wan Zul Haikal Hafiz
Md Pauzi, Ahmad Luqman
Chao, Loh Wei
Yin, Lau Su
author_facet Ismail, Hazwani
Wan Zul Haikal Hafiz
Md Pauzi, Ahmad Luqman
Chao, Loh Wei
Yin, Lau Su
author_sort Ismail, Hazwani
building UPM Institutional Repository
collection Online Access
description Coronavirus disease 2019 (COVID-19) is associated with an increased risk of death due to the sequelae of inflammation and thrombosis. Patients infected with COVID-19 are at risk of ischemic stroke due to the effects of inflammatory cytokine storm, platelet activation, endothelial dysfunction and prolonged stasis. We report a case of severe COVID-19 infection who developed acute ischemic stroke during the course of his illness. The patient did not carry any traditional risk of stroke or thromboembolic event and was vaccinated. He tested positive for COVID-19 infection, but due to respiratory distress, he was intubated and ventilated. On the 11th day in intensive care unit, he was noted to be hemiplegic with poor neurological recovery. Despite being on treatment dose enoxaparin, his computed tomography confirmed a lacunar infarct in his brain and bilateral pulmonary embolisms. Twenty-five days later, he remained well and was discharged home with dabigatran and atorvastatin.
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spelling upm-1070552024-10-17T03:51:41Z http://psasir.upm.edu.my/id/eprint/107055/ Collateral damage of COVID-19: late presentation of cerebrovascular accident Ismail, Hazwani Wan Zul Haikal Hafiz Md Pauzi, Ahmad Luqman Chao, Loh Wei Yin, Lau Su Coronavirus disease 2019 (COVID-19) is associated with an increased risk of death due to the sequelae of inflammation and thrombosis. Patients infected with COVID-19 are at risk of ischemic stroke due to the effects of inflammatory cytokine storm, platelet activation, endothelial dysfunction and prolonged stasis. We report a case of severe COVID-19 infection who developed acute ischemic stroke during the course of his illness. The patient did not carry any traditional risk of stroke or thromboembolic event and was vaccinated. He tested positive for COVID-19 infection, but due to respiratory distress, he was intubated and ventilated. On the 11th day in intensive care unit, he was noted to be hemiplegic with poor neurological recovery. Despite being on treatment dose enoxaparin, his computed tomography confirmed a lacunar infarct in his brain and bilateral pulmonary embolisms. Twenty-five days later, he remained well and was discharged home with dabigatran and atorvastatin. Malaysian Medical Association 2023-04 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/107055/1/Collateral%20damage%20of%20COVID-19_late%20presentation%20of%20cerebrovascular%20accident.pdf Ismail, Hazwani and Wan Zul Haikal Hafiz and Md Pauzi, Ahmad Luqman and Chao, Loh Wei and Yin, Lau Su (2023) Collateral damage of COVID-19: late presentation of cerebrovascular accident. Medical Journal of Malaysia Case Reports Journal, 2 (1). 34 - 36. ISSN 2948-3859 https://mjmcasereports.org/articles/2023/v2n1/collateral-damage-of-COVID-19.pdf
spellingShingle Ismail, Hazwani
Wan Zul Haikal Hafiz
Md Pauzi, Ahmad Luqman
Chao, Loh Wei
Yin, Lau Su
Collateral damage of COVID-19: late presentation of cerebrovascular accident
title Collateral damage of COVID-19: late presentation of cerebrovascular accident
title_full Collateral damage of COVID-19: late presentation of cerebrovascular accident
title_fullStr Collateral damage of COVID-19: late presentation of cerebrovascular accident
title_full_unstemmed Collateral damage of COVID-19: late presentation of cerebrovascular accident
title_short Collateral damage of COVID-19: late presentation of cerebrovascular accident
title_sort collateral damage of covid-19: late presentation of cerebrovascular accident
url http://psasir.upm.edu.my/id/eprint/107055/
http://psasir.upm.edu.my/id/eprint/107055/
http://psasir.upm.edu.my/id/eprint/107055/1/Collateral%20damage%20of%20COVID-19_late%20presentation%20of%20cerebrovascular%20accident.pdf