Clinical investigation of feline lower urinary tract disease, pathogenic bacteria and their antibiotic sensitivity at University Veterinary Hospital, Universiti Putra Malaysia

This study describes the clinical manifestation, bacterial pathogens and antibiotic sensitivity in cats diagnosed with Feline lower urinary tract disease (FLUTD). A total of 61 cats diagnosed with FLUTD from 2018 to 2019 were included in this study. Medical records were reviewed and rational antibio...

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Main Authors: Mazda, Delna, Lau, Seng Fong, Omar, Sharina
Format: Article
Language:English
Published: Chulalongkon University 2023
Online Access:http://psasir.upm.edu.my/id/eprint/107038/
http://psasir.upm.edu.my/id/eprint/107038/1/Clinical%20investigation%20of%20feline%20lower%20urinary%20tract%20disease%2C%20pathogenic%20bacteria%20and%20their%20antibiotic%20sensitivity%20at%20University%20Veterinary%20Hospital%2C%20Universiti%20Putra%20Malaysia.pdf
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author Mazda, Delna
Lau, Seng Fong
Omar, Sharina
author_facet Mazda, Delna
Lau, Seng Fong
Omar, Sharina
author_sort Mazda, Delna
building UPM Institutional Repository
collection Online Access
description This study describes the clinical manifestation, bacterial pathogens and antibiotic sensitivity in cats diagnosed with Feline lower urinary tract disease (FLUTD). A total of 61 cats diagnosed with FLUTD from 2018 to 2019 were included in this study. Medical records were reviewed and rational antibiotic therapy was calculated from the data collected on antibiotic sensitivity. Most cats in this study belonged to indoor multi-cat households with shared facilities. Thirty-two cats (52.45%) had positive urine cultures and were diagnosed with urinary tract infections. Staphylococcus species (23.2%), Enterococcus species (17.9%) and Escherichia coli (16.1%) were the most isolated bacteria. Escherichia coli demonstrated high levels of resistance to tested antibiotics, signifying the presence of resistant strains in Malaysia. The antibiotic impact factor calculated was 31.14 for cephalexin, 30.83 for amoxicillin/clavulanic acid, 19.82 for enrofloxacin and 19.43 for ceftriaxone. This study highlights the significance of urine culture and susceptibility testing prior to antibiotic administration. Based on the results of this study, empirical treatment can be provided based on the bacterial spectrum and the antibiotic impact factor.
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spelling upm-1070382024-10-17T03:54:53Z http://psasir.upm.edu.my/id/eprint/107038/ Clinical investigation of feline lower urinary tract disease, pathogenic bacteria and their antibiotic sensitivity at University Veterinary Hospital, Universiti Putra Malaysia Mazda, Delna Lau, Seng Fong Omar, Sharina This study describes the clinical manifestation, bacterial pathogens and antibiotic sensitivity in cats diagnosed with Feline lower urinary tract disease (FLUTD). A total of 61 cats diagnosed with FLUTD from 2018 to 2019 were included in this study. Medical records were reviewed and rational antibiotic therapy was calculated from the data collected on antibiotic sensitivity. Most cats in this study belonged to indoor multi-cat households with shared facilities. Thirty-two cats (52.45%) had positive urine cultures and were diagnosed with urinary tract infections. Staphylococcus species (23.2%), Enterococcus species (17.9%) and Escherichia coli (16.1%) were the most isolated bacteria. Escherichia coli demonstrated high levels of resistance to tested antibiotics, signifying the presence of resistant strains in Malaysia. The antibiotic impact factor calculated was 31.14 for cephalexin, 30.83 for amoxicillin/clavulanic acid, 19.82 for enrofloxacin and 19.43 for ceftriaxone. This study highlights the significance of urine culture and susceptibility testing prior to antibiotic administration. Based on the results of this study, empirical treatment can be provided based on the bacterial spectrum and the antibiotic impact factor. Chulalongkon University 2023-09-26 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/107038/1/Clinical%20investigation%20of%20feline%20lower%20urinary%20tract%20disease%2C%20pathogenic%20bacteria%20and%20their%20antibiotic%20sensitivity%20at%20University%20Veterinary%20Hospital%2C%20Universiti%20Putra%20Malaysia.pdf Mazda, Delna and Lau, Seng Fong and Omar, Sharina (2023) Clinical investigation of feline lower urinary tract disease, pathogenic bacteria and their antibiotic sensitivity at University Veterinary Hospital, Universiti Putra Malaysia. Thai Journal of Veterinary Medicine, 53 (2). 187 - 196. ISSN 2985-1130 https://he01.tci-thaijo.org/index.php/tjvm/article/view/266224
spellingShingle Mazda, Delna
Lau, Seng Fong
Omar, Sharina
Clinical investigation of feline lower urinary tract disease, pathogenic bacteria and their antibiotic sensitivity at University Veterinary Hospital, Universiti Putra Malaysia
title Clinical investigation of feline lower urinary tract disease, pathogenic bacteria and their antibiotic sensitivity at University Veterinary Hospital, Universiti Putra Malaysia
title_full Clinical investigation of feline lower urinary tract disease, pathogenic bacteria and their antibiotic sensitivity at University Veterinary Hospital, Universiti Putra Malaysia
title_fullStr Clinical investigation of feline lower urinary tract disease, pathogenic bacteria and their antibiotic sensitivity at University Veterinary Hospital, Universiti Putra Malaysia
title_full_unstemmed Clinical investigation of feline lower urinary tract disease, pathogenic bacteria and their antibiotic sensitivity at University Veterinary Hospital, Universiti Putra Malaysia
title_short Clinical investigation of feline lower urinary tract disease, pathogenic bacteria and their antibiotic sensitivity at University Veterinary Hospital, Universiti Putra Malaysia
title_sort clinical investigation of feline lower urinary tract disease, pathogenic bacteria and their antibiotic sensitivity at university veterinary hospital, universiti putra malaysia
url http://psasir.upm.edu.my/id/eprint/107038/
http://psasir.upm.edu.my/id/eprint/107038/
http://psasir.upm.edu.my/id/eprint/107038/1/Clinical%20investigation%20of%20feline%20lower%20urinary%20tract%20disease%2C%20pathogenic%20bacteria%20and%20their%20antibiotic%20sensitivity%20at%20University%20Veterinary%20Hospital%2C%20Universiti%20Putra%20Malaysia.pdf