Bioactive compounds of pigmented rice extracts reveal by NMR-based metabolomics
The present study determined total phenolic content (TPC), 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, ±-glucosidase, and nitric oxide (NO) inhibitory activities of black (BR), purple (PR), and red rice (RR) extracted with different polarity solvents and characterized the metabolites by...
| Main Authors: | , , , , , , , |
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| Format: | Article |
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Taylor and Francis
2023
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| Online Access: | http://psasir.upm.edu.my/id/eprint/106874/ |
| _version_ | 1848864841011298304 |
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| author | Netrprachit, Papichaya Nuangchamnong, Nitra Ramli, Nurul Shazini Maulidiani, Maulidiani Mediani, Ahmed Zolkeflee, Nur Khaleeda Zulaikha Jiamyangyuen, Sudarat Abas, Faridah |
| author_facet | Netrprachit, Papichaya Nuangchamnong, Nitra Ramli, Nurul Shazini Maulidiani, Maulidiani Mediani, Ahmed Zolkeflee, Nur Khaleeda Zulaikha Jiamyangyuen, Sudarat Abas, Faridah |
| author_sort | Netrprachit, Papichaya |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | The present study determined total phenolic content (TPC), 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, ±-glucosidase, and nitric oxide (NO) inhibitory activities of black (BR), purple (PR), and red rice (RR) extracted with different polarity solvents and characterized the metabolites by using the 1H NMR-based metabolomics approach. The methanol extract of RR had the highest DPPH scavenging and ±-glucosidase inhibitory activities. The water extracts of PR and RR exhibited the highest NO inhibitory activity with IC50 values of 176.28 ± 18.78 and 160.69 ± 14.83 µg/mL, respectively. The metabolites that contribute to radical scavenging and ±-glucosidase inhibitory activities of RR methanol extract were chlorogenic acid, protocatechuic acid, and tyrosine, whereas nicotinic acid, ³-aminobutyric acid, and citric acid were the metabolites that contributed to the NO inhibitory activity of RR water extract. The RR extracts are potential sources of bioactive compounds with antioxidant and NO inhibitory properties. |
| first_indexed | 2025-11-15T13:55:13Z |
| format | Article |
| id | upm-106874 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T13:55:13Z |
| publishDate | 2023 |
| publisher | Taylor and Francis |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1068742024-04-30T03:06:13Z http://psasir.upm.edu.my/id/eprint/106874/ Bioactive compounds of pigmented rice extracts reveal by NMR-based metabolomics Netrprachit, Papichaya Nuangchamnong, Nitra Ramli, Nurul Shazini Maulidiani, Maulidiani Mediani, Ahmed Zolkeflee, Nur Khaleeda Zulaikha Jiamyangyuen, Sudarat Abas, Faridah The present study determined total phenolic content (TPC), 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, ±-glucosidase, and nitric oxide (NO) inhibitory activities of black (BR), purple (PR), and red rice (RR) extracted with different polarity solvents and characterized the metabolites by using the 1H NMR-based metabolomics approach. The methanol extract of RR had the highest DPPH scavenging and ±-glucosidase inhibitory activities. The water extracts of PR and RR exhibited the highest NO inhibitory activity with IC50 values of 176.28 ± 18.78 and 160.69 ± 14.83 µg/mL, respectively. The metabolites that contribute to radical scavenging and ±-glucosidase inhibitory activities of RR methanol extract were chlorogenic acid, protocatechuic acid, and tyrosine, whereas nicotinic acid, ³-aminobutyric acid, and citric acid were the metabolites that contributed to the NO inhibitory activity of RR water extract. The RR extracts are potential sources of bioactive compounds with antioxidant and NO inhibitory properties. Taylor and Francis 2023 Article PeerReviewed Netrprachit, Papichaya and Nuangchamnong, Nitra and Ramli, Nurul Shazini and Maulidiani, Maulidiani and Mediani, Ahmed and Zolkeflee, Nur Khaleeda Zulaikha and Jiamyangyuen, Sudarat and Abas, Faridah (2023) Bioactive compounds of pigmented rice extracts reveal by NMR-based metabolomics. CYTA-Journal of Food, 21 (1). 760 - 770. ISSN 1947-6337; ESSN: 1947-6345 https://www.tandfonline.com/doi/full/10.1080/19476337.2023.2284330 10.1080/19476337.2023.2284330 |
| spellingShingle | Netrprachit, Papichaya Nuangchamnong, Nitra Ramli, Nurul Shazini Maulidiani, Maulidiani Mediani, Ahmed Zolkeflee, Nur Khaleeda Zulaikha Jiamyangyuen, Sudarat Abas, Faridah Bioactive compounds of pigmented rice extracts reveal by NMR-based metabolomics |
| title | Bioactive compounds of pigmented rice extracts reveal by NMR-based metabolomics |
| title_full | Bioactive compounds of pigmented rice extracts reveal by NMR-based metabolomics |
| title_fullStr | Bioactive compounds of pigmented rice extracts reveal by NMR-based metabolomics |
| title_full_unstemmed | Bioactive compounds of pigmented rice extracts reveal by NMR-based metabolomics |
| title_short | Bioactive compounds of pigmented rice extracts reveal by NMR-based metabolomics |
| title_sort | bioactive compounds of pigmented rice extracts reveal by nmr-based metabolomics |
| url | http://psasir.upm.edu.my/id/eprint/106874/ http://psasir.upm.edu.my/id/eprint/106874/ http://psasir.upm.edu.my/id/eprint/106874/ |