Fractional exhaled nitric oxide (FeNO) and respiratory symptoms in junior high school students in Penang, Malaysia: the role of household exposure
We studied associations between fractional exhaled nitric oxide (FeNO), health and household exposure among school children (N = 348) in Penang, Malaysia. Multiple logistic regression and linear mixed models were applied. Overall, 46.0 had elevated FeNO (>20 ppb) and 10.6 diagnosed asthma. Male g...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Taylor and Francis Ltd.
2024
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| Online Access: | http://psasir.upm.edu.my/id/eprint/105880/ http://psasir.upm.edu.my/id/eprint/105880/1/Fractional%20exhaled%20nitric%20oxide%20%20FeNO%20%20and%20respiratory%20symptoms%20in%20junior%20high%20school%20students%20in%20Penang%20%20Malaysia%20%20the%20role%20of%20household%20exposure.pdf |
| _version_ | 1848864632551243776 |
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| author | Norback, Dan Hashim, Jamal Hisham Hashim, Zailina Wieslander, Gunilla |
| author_facet | Norback, Dan Hashim, Jamal Hisham Hashim, Zailina Wieslander, Gunilla |
| author_sort | Norback, Dan |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | We studied associations between fractional exhaled nitric oxide (FeNO), health and household exposure among school children (N = 348) in Penang, Malaysia. Multiple logistic regression and linear mixed models were applied. Overall, 46.0 had elevated FeNO (>20 ppb) and 10.6 diagnosed asthma. Male gender (p = 0.002), parental asthma or allergy (p = 0.047), cat allergy (p = 0.009) and seafood allergy (p < 0.001), diagnosed asthma (p = 0.001), wheeze (p = 0.001), ocular symptoms (p = 0.001), rhinitis (p = 0.002) and respiratory infections (p = 0.004) were all associated with FeNO. Students exposed to ETS had lower FeNO (p = 0.05). Dampness and mould was associated with wheeze (p = 0.038), especially in wooden homes (interaction p = 0.042) and among students with elevated FeNO (interaction p = 0.024). Cat keeping increased rhinitis (p = 0.041) and respiratory infections (p = 0.008) and modified the dampness associations. In conclusion, FeNO can be associated with ocular and respiratory symptoms. Elevated FeNO, cat keeping and a wooden house can enhance the risk of wheeze when exposed to dampness and mould. |
| first_indexed | 2025-11-15T13:51:54Z |
| format | Article |
| id | upm-105880 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T13:51:54Z |
| publishDate | 2024 |
| publisher | Taylor and Francis Ltd. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1058802024-07-12T08:15:29Z http://psasir.upm.edu.my/id/eprint/105880/ Fractional exhaled nitric oxide (FeNO) and respiratory symptoms in junior high school students in Penang, Malaysia: the role of household exposure Norback, Dan Hashim, Jamal Hisham Hashim, Zailina Wieslander, Gunilla We studied associations between fractional exhaled nitric oxide (FeNO), health and household exposure among school children (N = 348) in Penang, Malaysia. Multiple logistic regression and linear mixed models were applied. Overall, 46.0 had elevated FeNO (>20 ppb) and 10.6 diagnosed asthma. Male gender (p = 0.002), parental asthma or allergy (p = 0.047), cat allergy (p = 0.009) and seafood allergy (p < 0.001), diagnosed asthma (p = 0.001), wheeze (p = 0.001), ocular symptoms (p = 0.001), rhinitis (p = 0.002) and respiratory infections (p = 0.004) were all associated with FeNO. Students exposed to ETS had lower FeNO (p = 0.05). Dampness and mould was associated with wheeze (p = 0.038), especially in wooden homes (interaction p = 0.042) and among students with elevated FeNO (interaction p = 0.024). Cat keeping increased rhinitis (p = 0.041) and respiratory infections (p = 0.008) and modified the dampness associations. In conclusion, FeNO can be associated with ocular and respiratory symptoms. Elevated FeNO, cat keeping and a wooden house can enhance the risk of wheeze when exposed to dampness and mould. Taylor and Francis Ltd. 2024 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/105880/1/Fractional%20exhaled%20nitric%20oxide%20%20FeNO%20%20and%20respiratory%20symptoms%20in%20junior%20high%20school%20students%20in%20Penang%20%20Malaysia%20%20the%20role%20of%20household%20exposure.pdf Norback, Dan and Hashim, Jamal Hisham and Hashim, Zailina and Wieslander, Gunilla (2024) Fractional exhaled nitric oxide (FeNO) and respiratory symptoms in junior high school students in Penang, Malaysia: the role of household exposure. International Journal of Environmental Health Research, 34 (1). pp. 213-224. ISSN 0960-3123; ESSN: 1369-1619 https://www.tandfonline.com/doi/full/10.1080/09603123.2022.2143482 10.1080/09603123.2022.2143482 |
| spellingShingle | Norback, Dan Hashim, Jamal Hisham Hashim, Zailina Wieslander, Gunilla Fractional exhaled nitric oxide (FeNO) and respiratory symptoms in junior high school students in Penang, Malaysia: the role of household exposure |
| title | Fractional exhaled nitric oxide (FeNO) and respiratory symptoms in junior high school students in Penang, Malaysia: the role of household exposure |
| title_full | Fractional exhaled nitric oxide (FeNO) and respiratory symptoms in junior high school students in Penang, Malaysia: the role of household exposure |
| title_fullStr | Fractional exhaled nitric oxide (FeNO) and respiratory symptoms in junior high school students in Penang, Malaysia: the role of household exposure |
| title_full_unstemmed | Fractional exhaled nitric oxide (FeNO) and respiratory symptoms in junior high school students in Penang, Malaysia: the role of household exposure |
| title_short | Fractional exhaled nitric oxide (FeNO) and respiratory symptoms in junior high school students in Penang, Malaysia: the role of household exposure |
| title_sort | fractional exhaled nitric oxide (feno) and respiratory symptoms in junior high school students in penang, malaysia: the role of household exposure |
| url | http://psasir.upm.edu.my/id/eprint/105880/ http://psasir.upm.edu.my/id/eprint/105880/ http://psasir.upm.edu.my/id/eprint/105880/ http://psasir.upm.edu.my/id/eprint/105880/1/Fractional%20exhaled%20nitric%20oxide%20%20FeNO%20%20and%20respiratory%20symptoms%20in%20junior%20high%20school%20students%20in%20Penang%20%20Malaysia%20%20the%20role%20of%20household%20exposure.pdf |