Performance analysis and green profile assessment of synthesised amino-functionalised magnetic silica nanocomposite for magnetic micro-solid phase extraction of penicillin antibiotics from milk samples
This study explored the synthesis and application of amino-functionalised magnetic silica (Fe3O4 @mSiO2-NH2) nanocomposite as a selective sorbent for the extraction of penicillin antibiotics (PENs) from milk samples via magnetic micro-solid phase extraction (M-µ-SPE). The physicochemical characteris...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
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Academic Press Inc.
2024
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| Online Access: | http://psasir.upm.edu.my/id/eprint/105858/ |
| _version_ | 1848864627048316928 |
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| author | Abd Halim, Wan Ibrahim Thani Abd Hamid, Muhammad Ariffuddin Aziz, Mohd Yusmaidie Mohd Din, Azam Taufik Mohamad Zain, Nur Nadhirah Kamaruzaman, Sazlinda Nishiyama, Norikazu Li, Xinyu Hirota, Yuichiro Yahaya, Noorfatimah |
| author_facet | Abd Halim, Wan Ibrahim Thani Abd Hamid, Muhammad Ariffuddin Aziz, Mohd Yusmaidie Mohd Din, Azam Taufik Mohamad Zain, Nur Nadhirah Kamaruzaman, Sazlinda Nishiyama, Norikazu Li, Xinyu Hirota, Yuichiro Yahaya, Noorfatimah |
| author_sort | Abd Halim, Wan Ibrahim Thani |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | This study explored the synthesis and application of amino-functionalised magnetic silica (Fe3O4 @mSiO2-NH2) nanocomposite as a selective sorbent for the extraction of penicillin antibiotics (PENs) from milk samples via magnetic micro-solid phase extraction (M-µ-SPE). The physicochemical characteristics of the synthesised sorbent were evaluated through important spectroscopy analyses. The adopted M-µ-SPE conditions were: 25 mg of Fe3O4 @mSiO2-NH2; pH 4; 3 min of extraction time; 1 min of desorption time; acetonitrile as the desorption solvent; 10 of salt addition; and 30 mL sample. Under the optimum conditions, the developed method demonstrated satisfactory from 10 to 500 µg/L (r2≥0.9986), low limits of detection (2.5–3.1 µg/L), high analytes recovery (85.2–106.7), and good precision (RSDs≤8,n = 5). The proposed method is rapid, simple, inexpensive, and shows good sensitivity when compared to previously developed methods. This study provides new insight into the development of a new sorbent for PENs and new microscale sample preparation for monitoring PENs in complex milk matrices. |
| first_indexed | 2025-11-15T13:51:49Z |
| format | Article |
| id | upm-105858 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T13:51:49Z |
| publishDate | 2024 |
| publisher | Academic Press Inc. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1058582024-03-22T01:31:16Z http://psasir.upm.edu.my/id/eprint/105858/ Performance analysis and green profile assessment of synthesised amino-functionalised magnetic silica nanocomposite for magnetic micro-solid phase extraction of penicillin antibiotics from milk samples Abd Halim, Wan Ibrahim Thani Abd Hamid, Muhammad Ariffuddin Aziz, Mohd Yusmaidie Mohd Din, Azam Taufik Mohamad Zain, Nur Nadhirah Kamaruzaman, Sazlinda Nishiyama, Norikazu Li, Xinyu Hirota, Yuichiro Yahaya, Noorfatimah This study explored the synthesis and application of amino-functionalised magnetic silica (Fe3O4 @mSiO2-NH2) nanocomposite as a selective sorbent for the extraction of penicillin antibiotics (PENs) from milk samples via magnetic micro-solid phase extraction (M-µ-SPE). The physicochemical characteristics of the synthesised sorbent were evaluated through important spectroscopy analyses. The adopted M-µ-SPE conditions were: 25 mg of Fe3O4 @mSiO2-NH2; pH 4; 3 min of extraction time; 1 min of desorption time; acetonitrile as the desorption solvent; 10 of salt addition; and 30 mL sample. Under the optimum conditions, the developed method demonstrated satisfactory from 10 to 500 µg/L (r2≥0.9986), low limits of detection (2.5–3.1 µg/L), high analytes recovery (85.2–106.7), and good precision (RSDs≤8,n = 5). The proposed method is rapid, simple, inexpensive, and shows good sensitivity when compared to previously developed methods. This study provides new insight into the development of a new sorbent for PENs and new microscale sample preparation for monitoring PENs in complex milk matrices. Academic Press Inc. 2024 Article PeerReviewed Abd Halim, Wan Ibrahim Thani and Abd Hamid, Muhammad Ariffuddin and Aziz, Mohd Yusmaidie and Mohd Din, Azam Taufik and Mohamad Zain, Nur Nadhirah and Kamaruzaman, Sazlinda and Nishiyama, Norikazu and Li, Xinyu and Hirota, Yuichiro and Yahaya, Noorfatimah (2024) Performance analysis and green profile assessment of synthesised amino-functionalised magnetic silica nanocomposite for magnetic micro-solid phase extraction of penicillin antibiotics from milk samples. Journal of Food Composition and Analysis, 127. art. no. 105944. pp. 1-10. ISSN 0889-1575; ESSN: 1096-0481 https://www.sciencedirect.com/science/article/pii/S0889157523008189 10.1016/j.jfca.2023.105944 |
| spellingShingle | Abd Halim, Wan Ibrahim Thani Abd Hamid, Muhammad Ariffuddin Aziz, Mohd Yusmaidie Mohd Din, Azam Taufik Mohamad Zain, Nur Nadhirah Kamaruzaman, Sazlinda Nishiyama, Norikazu Li, Xinyu Hirota, Yuichiro Yahaya, Noorfatimah Performance analysis and green profile assessment of synthesised amino-functionalised magnetic silica nanocomposite for magnetic micro-solid phase extraction of penicillin antibiotics from milk samples |
| title | Performance analysis and green profile assessment of synthesised amino-functionalised magnetic silica nanocomposite for magnetic micro-solid phase extraction of penicillin antibiotics from milk samples |
| title_full | Performance analysis and green profile assessment of synthesised amino-functionalised magnetic silica nanocomposite for magnetic micro-solid phase extraction of penicillin antibiotics from milk samples |
| title_fullStr | Performance analysis and green profile assessment of synthesised amino-functionalised magnetic silica nanocomposite for magnetic micro-solid phase extraction of penicillin antibiotics from milk samples |
| title_full_unstemmed | Performance analysis and green profile assessment of synthesised amino-functionalised magnetic silica nanocomposite for magnetic micro-solid phase extraction of penicillin antibiotics from milk samples |
| title_short | Performance analysis and green profile assessment of synthesised amino-functionalised magnetic silica nanocomposite for magnetic micro-solid phase extraction of penicillin antibiotics from milk samples |
| title_sort | performance analysis and green profile assessment of synthesised amino-functionalised magnetic silica nanocomposite for magnetic micro-solid phase extraction of penicillin antibiotics from milk samples |
| url | http://psasir.upm.edu.my/id/eprint/105858/ http://psasir.upm.edu.my/id/eprint/105858/ http://psasir.upm.edu.my/id/eprint/105858/ |