Targeted delivery of short hairpin RNA expressing plasmid using hepatitis B virus-like particle for bcl-2 gene silencing in cervical cancer cells

QR Code

Targeted delivery of short hairpin RNA expressing plasmid using hepatitis B virus-like particle for bcl-2 gene silencing in cervical cancer cells

Gene therapy research has advanced rapidly to clinical trials, but it is greatly hampered by the unstable nucleic acids particularly short interference RNA (siRNA) packaged inside carriers, and the lack of specificity towards targeted sites in the body. Hence, development of a stable carrier with sp...

Full description

Bibliographic Details
Main Author:	Akwiditya, Made Angga
Format:	Thesis
Language:	English
Published:	2021
Subjects:	Gene therapy Hepatitis B virus
Online Access:	http://psasir.upm.edu.my/id/eprint/104615/ http://psasir.upm.edu.my/id/eprint/104615/1/FBSB%202022%2016%20IR.pdf

Similar Items

Hepatitis B virus-like particle: targeted delivery of plasmid expressing short hairpin RNA for silencing the Bcl-2 gene in cervical cancer cells
by: Akwiditya, Made Angga, et al.
Published: (2021)

Co-infections of hepatitis B patients with other hepatitis viruses and their serological, biological and prognostic markers
by: Hudu Abdullahi, Shuaibu
Published: (2017)

Investigation of Hepatitis B virus entry mechanism
by: Raymond, Chidinma
Published: (2022)

Novel entry pathways for Hepatitis B virus
by: Parmar, Devan
Published: (2023)

Display of the pres regions of the surface antigen of Hepatitis B virus on M13 and T7 Bactetiophages
by: Kok, Wai Ling
Published: (2001)

Shielding of virus-like nanoparticles of hepatitis B core antigen by poly(2-oxazoline) for reduced antigenicity
by: Fam, See Yee
Published: (2021)

Expression, purification and structural characterisation of Hepatitis B virus core antigen with an N-terminal extension
by: Yoon, Kam Yee
Published: (2013)

Development of anti-hepatitis B virus core antigen biosensor using gold nanoparticle-decorated reduced graphene oxide
by: Abd Muain, Mohamad Farid
Published: (2019)

Selection of High Affinity Peptides Against Hepatitis B Core Antigen from a Phage-Displayed Cyclic Peptide Library
by: Ho, Kok Lian
Published: (2002)

Targeted 5-fluorouracil-1-acetic acid delivery utilising cell penetrating peptide conjugated hepatitis b virus-like nanoparticles to squamous cell carcinoma A431
by: Gan, Bee Koon
Published: (2020)

Recombinant human L-ficolin directly neutralizes hepatitis C virus entry
by: Hamed, Mohamed R., et al.
Published: (2014)

Recombinant hepatitis B virus core particles: association, dissociation and encapsidation of green fluorescent protein.
by: Lee, Khai Wooi, et al.
Published: (2008)

Hepatitis B capsid as a delivery vehicle into mammalian cells
by: Lee, Khai Wooi
Published: (2012)

Molecular characterization and methylation status of torque teno virus isolation among hepatitis patients in a public hospital in Pahang, Malaysia
by: Hazanuddin, Siti Nurzulaikha
Published: (2020)

Hepatic elastin content is predictive of adverse outcome in advanced fibrotic liver disease
by: Kendall, Timothy, et al.
Published: (2018)

Molecular epidemiology and antiviral resistance characterization of Hepatitis C virus circulating in Africa and Brazil
by: Adeboyejo, Kazeem Adeyinka
Published: (2020)

Antigenicity and immunogenicity of the immunodominant region of hepatitis B surface antigen displayed on bacteriophage T7
by: Tan, Geok Hun, et al.
Published: (2005)

Purification and characterization of polyclonal anti-hepatitis B core antigen immunoglobulin G from rabbit serum
by: Sayed Hitam, Sharifah Mariam
Published: (2016)

Authenticity and Diversity: Enhancing Australian Hepatitis C Prevention Messages
by: Winter, R., et al.
Published: (2013)

Molecular prevalence and genome analysis of domestic cat hepadnavirus in Malaysia
by: Anpuanandam, Khanmani
Published: (2021)

The effects of the human innate pattern recognition receptor L-ficolin and its variants against Hepatitis C virus infection
by: Mason, Christopher Paul
Published: (2019)

Development and characterization of a human monoclonal antibody targeting the N-terminal region of hepatitis C virus envelope glycoprotein E1
by: Mesalam, Ahmed Atef, et al.
Published: (2018)

Comorbities and medications of patients with chronic hepatitis C under specialist care in the UK
by: Hudson, Benjamin, et al.
Published: (2017)

The effects of probiotics and symbiotics on risk factors for hepatic encephalopathy
by: Viramontes Hörner, Daniela, et al.
Published: (2017)

Macrobrachium rosenbergii de Man nodavirus capsid displaying Influenza A and Hepatitis B virus immunodominant regions induce humoral and cellular immune responses in mice
by: Yong, Chean Yeah
Published: (2015)

The cost of treatment failure: resource use and costs incurred by hepatitis C virus genotype 1-infected patients who do or do not achieve sustained virological response to therapy
by: Backx, M., et al.
Published: (2014)

Comparison Of Extraction Methods For Detecting Hepatitis A Virus In Shellfish (Mystilus Galloprovincialis) Using Tissue Culture Titration, RT-Nested PCR And Real Time RT-PCR
by: Yong, Han Tek
Published: (2009)

Host genetic factors associated with hepatocellular carcinoma in patients with hepatitis C virus infection: a systematic review
by: Walker, Alex J., et al.
Published: (2018)

Detection of Hepatitis B Core Antigen using a Fusion Bacteriophage
by: Hasmoni, Siti Salwa
Published: (2005)

Evaluation of post infant hepatitis B vaccination among healthy vaccinees and molecular detection of occult hepatitis B among healthy volunteers
by: Shuaibu, Hudu Abdullahi
Published: (2014)

Outcomes after successful direct acting antiviral therapy for patients with chronic hepatitis C and decompensated cirrhosis
by: Cheung, Michelle C.M., et al.
Published: (2016)

Effectiveness of an education intervention on Hepatitis C treatment adherence among Libyan patients in a medical center in Tripoli
by: Adam, Samia Ibrahim Mohamed
Published: (2018)

Optimization for detecting the efficiency of viral-vectored gene delivery via intratumoural route in murine model
by: Mustafa, Nor Hidayah
Published: (2015)

Development of surface plasmon resonance based assay for simultaneous detection of Hepatitis C and B viral infections
by: Akhavanrezaei, Morvarid
Published: (2015)

Does informing people who inject drugs of their hepatitis C status influence their injecting behavior? Analysis of the Networks II study
by: Aspinall, E., et al.
Published: (2014)

Combination therapy using plasmid DNA-mediated VP3 and SHCD147 genes for colon cancer in a murine model
by: Ismail, Ruzila
Published: (2014)

A novel neutralizing human monoclonal antibody broadly abrogates hepatitis C virus infection in vitro and in vivo
by: Desombere, Isabelle, et al.
Published: (2017)

Periportal CD4+ Cell Infiltration Increases in HIV/Hepatitis C Virus–Coinfected Patients Commencing ART, Whereas CD8+ Cells Clear From the Liver
by: Gani, R., et al.
Published: (2014)

Production of Hepatitis B Viral Antigens and Antibodies using Phage Display Technology for the Development of a Diagnostic Test
by: Tan, Geok Hun
Published: (2006)

Risk factors for hepatitis c virus infection among adult patients at a public hospital in Kedah, Malaysia
by: Mohd Suan, Mohd Azri
Published: (2019)