Predicting deleterious non-synonymous single nucleotide polymorphisms nsSNPs of HRAS gene and in-silico evaluation of their structural and functional consequences towards diagnosis and prognosis of cancer

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Predicting deleterious non-synonymous single nucleotide polymorphisms nsSNPs of HRAS gene and in-silico evaluation of their structural and functional consequences towards diagnosis and prognosis of cancer

The Harvey rat sarcoma (HRAS) proto-oncogene belongs to the RAS family and is one of the pathogenic genes that cause cancer. Deleterious nsSNPs might have adverse consequences at the protein level. This study aimed to investigate deleterious nsSNPs in the HRAS gene in predicting structural alteratio...

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Bibliographic Details
Main Authors:	Chai, Chuan-Yu, Maran, Sathiya, Thew, Hin-Yee, Tan, Yong-Chiang, Nik Abd Rahman, Nik Mohd Afizan, Cheng, Wan-Hee, Lai, Kok-Song, Loh, Jiun-Yan, Yap, Wai-Sum
Format:	Article
Published:	MDPI 2022
Online Access:	http://psasir.upm.edu.my/id/eprint/102829/

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