Phenotypic profile of Aedes albopictus (skuse) exposed to pyrethroid-based mat vaporizers and underlying detoxification mechanisms: a statewide report in Selangor, Malaysia
This study examines the biological efficacy of four mosquito mat vaporizers each containing different active ingredients: prallethrin with PBO, dimefluthrin, prallethrin, and d-allethrin. The glass chamber assay was used to evaluate their efficacy on Aedes albopictus (Skuse) (Diptera: Culicidae) fro...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier Ireland
2022
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| Online Access: | http://psasir.upm.edu.my/id/eprint/102746/ http://psasir.upm.edu.my/id/eprint/102746/1/102746.pdf |
| _version_ | 1848863866005487616 |
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| author | Hizayu, Taib Azratul Chen, Chee Dhang Lau, Koon Weng Wahid, Noor Azrizal Tan, Tiong Kai Lim, Yvonne Ai Lian Azirun, Mohd Sofian Low, Van Lun |
| author_facet | Hizayu, Taib Azratul Chen, Chee Dhang Lau, Koon Weng Wahid, Noor Azrizal Tan, Tiong Kai Lim, Yvonne Ai Lian Azirun, Mohd Sofian Low, Van Lun |
| author_sort | Hizayu, Taib Azratul |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | This study examines the biological efficacy of four mosquito mat vaporizers each containing different active ingredients: prallethrin with PBO, dimefluthrin, prallethrin, and d-allethrin. The glass chamber assay was used to evaluate their efficacy on Aedes albopictus (Skuse) (Diptera: Culicidae) from nine districts in Selangor, Malaysia. Aedes albopictus exhibited different knockdown rates, with 50% knockdown times, KT50, varying from 1.19 to 2.00 min, 1.22 to 2.20 min, 1.39 to 5.85 min, and 1.39 to 1.92 min for prallethrin with PBO, dimefluthrin, prallethrin and d-allethrin, respectively. In general, all populations of Ae. albopictus were completely knocked down after exposure to all active ingredients except Hulu Selangor population, which showed 96.00% knockdown against d-allethrin. On the contrary, mortality rates were observed from 84.00–100.00%, 84.00–100.00%, 90.67–100.00% and 90.67–100.00% in populations tested with prallethrin with PBO, dimefluthrin, prallethrin and d-allethrin, respectively. Moreover, significant correlations between mortality rates of prallethrin with PBO vs dimefluthrin (r = 0.836, P = 0.003), prallethrin with PBO vs prallethrin (r = 0.760, P = 0.011), and prallethrin vs d-allethrin (r = 0.694, P = 0.026) were also observed, suggesting cross-resistance among pyrethroids. d-allethrin was found to be high in insecticidal activity, followed by prallethrin, prallethrin with PBO, and dimefluthrin. In consistent with mortality due to insecticide exposure, elevated levels of enzyme activities were also demonstrated in Sabak Bernam, Hulu Selangor, Gombak, Petaling, Hulu Langat and Klang populations. |
| first_indexed | 2025-11-15T13:39:43Z |
| format | Article |
| id | upm-102746 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T13:39:43Z |
| publishDate | 2022 |
| publisher | Elsevier Ireland |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1027462025-07-17T04:20:44Z http://psasir.upm.edu.my/id/eprint/102746/ Phenotypic profile of Aedes albopictus (skuse) exposed to pyrethroid-based mat vaporizers and underlying detoxification mechanisms: a statewide report in Selangor, Malaysia Hizayu, Taib Azratul Chen, Chee Dhang Lau, Koon Weng Wahid, Noor Azrizal Tan, Tiong Kai Lim, Yvonne Ai Lian Azirun, Mohd Sofian Low, Van Lun This study examines the biological efficacy of four mosquito mat vaporizers each containing different active ingredients: prallethrin with PBO, dimefluthrin, prallethrin, and d-allethrin. The glass chamber assay was used to evaluate their efficacy on Aedes albopictus (Skuse) (Diptera: Culicidae) from nine districts in Selangor, Malaysia. Aedes albopictus exhibited different knockdown rates, with 50% knockdown times, KT50, varying from 1.19 to 2.00 min, 1.22 to 2.20 min, 1.39 to 5.85 min, and 1.39 to 1.92 min for prallethrin with PBO, dimefluthrin, prallethrin and d-allethrin, respectively. In general, all populations of Ae. albopictus were completely knocked down after exposure to all active ingredients except Hulu Selangor population, which showed 96.00% knockdown against d-allethrin. On the contrary, mortality rates were observed from 84.00–100.00%, 84.00–100.00%, 90.67–100.00% and 90.67–100.00% in populations tested with prallethrin with PBO, dimefluthrin, prallethrin and d-allethrin, respectively. Moreover, significant correlations between mortality rates of prallethrin with PBO vs dimefluthrin (r = 0.836, P = 0.003), prallethrin with PBO vs prallethrin (r = 0.760, P = 0.011), and prallethrin vs d-allethrin (r = 0.694, P = 0.026) were also observed, suggesting cross-resistance among pyrethroids. d-allethrin was found to be high in insecticidal activity, followed by prallethrin, prallethrin with PBO, and dimefluthrin. In consistent with mortality due to insecticide exposure, elevated levels of enzyme activities were also demonstrated in Sabak Bernam, Hulu Selangor, Gombak, Petaling, Hulu Langat and Klang populations. Elsevier Ireland 2022 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/102746/1/102746.pdf Hizayu, Taib Azratul and Chen, Chee Dhang and Lau, Koon Weng and Wahid, Noor Azrizal and Tan, Tiong Kai and Lim, Yvonne Ai Lian and Azirun, Mohd Sofian and Low, Van Lun (2022) Phenotypic profile of Aedes albopictus (skuse) exposed to pyrethroid-based mat vaporizers and underlying detoxification mechanisms: a statewide report in Selangor, Malaysia. Parasitology International, 86. art. no. 102483. pp. 1-8. ISSN 1383-5769; eISSN: 1873-0329 https://linkinghub.elsevier.com/retrieve/pii/S1383576921002014 10.1016/j.parint.2021.102483 |
| spellingShingle | Hizayu, Taib Azratul Chen, Chee Dhang Lau, Koon Weng Wahid, Noor Azrizal Tan, Tiong Kai Lim, Yvonne Ai Lian Azirun, Mohd Sofian Low, Van Lun Phenotypic profile of Aedes albopictus (skuse) exposed to pyrethroid-based mat vaporizers and underlying detoxification mechanisms: a statewide report in Selangor, Malaysia |
| title | Phenotypic profile of Aedes albopictus (skuse) exposed to pyrethroid-based mat vaporizers and underlying detoxification mechanisms: a statewide report in Selangor, Malaysia |
| title_full | Phenotypic profile of Aedes albopictus (skuse) exposed to pyrethroid-based mat vaporizers and underlying detoxification mechanisms: a statewide report in Selangor, Malaysia |
| title_fullStr | Phenotypic profile of Aedes albopictus (skuse) exposed to pyrethroid-based mat vaporizers and underlying detoxification mechanisms: a statewide report in Selangor, Malaysia |
| title_full_unstemmed | Phenotypic profile of Aedes albopictus (skuse) exposed to pyrethroid-based mat vaporizers and underlying detoxification mechanisms: a statewide report in Selangor, Malaysia |
| title_short | Phenotypic profile of Aedes albopictus (skuse) exposed to pyrethroid-based mat vaporizers and underlying detoxification mechanisms: a statewide report in Selangor, Malaysia |
| title_sort | phenotypic profile of aedes albopictus (skuse) exposed to pyrethroid-based mat vaporizers and underlying detoxification mechanisms: a statewide report in selangor, malaysia |
| url | http://psasir.upm.edu.my/id/eprint/102746/ http://psasir.upm.edu.my/id/eprint/102746/ http://psasir.upm.edu.my/id/eprint/102746/ http://psasir.upm.edu.my/id/eprint/102746/1/102746.pdf |